(Q40797123)

23 September 2017

title

Adenovirus L4-100K assembly protein is a granzyme B substrate that potently inhibits granzyme B-mediated cell death (English)

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23 September 2017

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F Andrade

1

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23 September 2017

H G Bull

2

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23 September 2017

N A Thornberry

3

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23 September 2017

G W Ketner

4

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23 September 2017

L A Casciola-Rosen

5

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23 September 2017

A Rosen

6

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23 September 2017

language of work or name

English

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publication date

1 June 2001

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23 September 2017

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23 September 2017

volume

14

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23 September 2017

issue

6

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23 September 2017

page(s)

751-761

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Adenovirus 5 DNA sequences present and RNA sequences transcribed in transformed human embryo kidney cells (HEK-Ad-5 or 293)

23 September 2017

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Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

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Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation

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Cleavage by granzyme B is strongly predictive of autoantigen status: implications for initiation of autoimmunity

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Assembly of adenovirus major capsid protein is mediated by a nonvirion protein

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Interaction of the adenovirus 14.7-kDa protein with FLICE inhibits Fas ligand-induced apoptosis

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IAP family proteins--suppressors of apoptosis

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Granzyme A-deficient mice retain potent cell-mediated cytotoxicity.

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Granzyme B/Perforin-Mediated Apoptosis of Jurkat Cells Results in Cleavage of Poly(ADP-ribose) Polymerase to the 89-kDa Apoptotic Fragment and Less Abundant 64-kDa Fragment

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Definition and redesign of the extended substrate specificity of granzyme B.

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Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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7 January 2021

Mitochondria-dependent and -independent regulation of Granzyme B-induced apoptosis

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7 January 2021

Differential inhibition of the Fas- and granule-mediated cytolysis pathways by the orthopoxvirus cytokine response modifier A/SPI-2 and SPI-1 protein

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7 January 2021

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7 January 2021

A central role of perforin in cytolysis?

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Granzyme B is inhibited by the cowpox virus serpin cytokine response modifier A.

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7 January 2021

Murine cytomegalovirus replication in salivary glands is controlled by both perforin and granzymes during acute infection

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7 January 2021

Caspases: intracellular signaling by proteolysis

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7 January 2021

Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases

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7 January 2021

Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions

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7 January 2021

Granzyme A initiates an alternative pathway for granule-mediated apoptosis.

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7 January 2021

In vitro- and ex vivo-derived cytolytic leukocytes from granzyme A x B double knockout mice are defective in granule-mediated apoptosis but not lysis of target cells

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7 January 2021

A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes

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7 January 2021

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

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7 January 2021

Granule-mediated killing: pathways for granzyme B-initiated apoptosis.

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7 January 2021

CrmA, a poxvirus-encoded serpin, inhibits cytotoxic T-lymphocyte-mediated apoptosis

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7 January 2021

DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis

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7 January 2021

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

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7 January 2021

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

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7 January 2021

Forced degradation of Fas inhibits apoptosis in adenovirus-infected cells

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7 January 2021

Viral subversion of the immune system

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7 January 2021

CTL granules: evolution of vesicles essential for combating virus infections

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7 January 2021

Human plasma proteinase inhibitors

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7 January 2021

Immune responses to adenoviruses: viral evasion mechanisms and their implications for the clinic.

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7 January 2021

10.1016/S1074-7613(01)00149-2

Identifiers

DOI

1 reference

23 September 2017

1 reference