(Q61862461)

English

Genetic variation within the NR1H2 gene encoding liver X receptor β associates with insulin secretion in subjects at increased risk for type 2 diabetes

scientific article published on 2 November 2010

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21042792%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Genetic variation within the NR1H2 gene encoding liver X receptor β associates with insulin secretion in subjects at increased risk for type 2 diabetes (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21042792%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

type 2 diabetes

1 reference

based on heuristic

inferred from title

genetic variation

1 reference

based on heuristic

inferred from title

4

1 reference

Europe PubMed Central

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15 January 2020

7

1 reference

Europe PubMed Central

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15 January 2020

Andreas Fritsche

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object named as

Andreas Fritsche

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21042792%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Fausto Machicao

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object named as

Fausto Machicao

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21042792%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Caroline Ketterer

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object named as

Caroline Ketterer

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21042792%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Hans-Ulrich Häring

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object named as

Hans-Ulrich Häring

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21042792%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

Karsten Müssig

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object named as

Karsten Müssig

1 reference

Europe PubMed Central

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15 January 2020

publication date

2 November 2010

1 reference

Europe PubMed Central

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15 January 2020

Journal of Molecular Medicine

1 reference

Europe PubMed Central

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15 January 2020

89

1 reference

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15 January 2020

1

1 reference

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15 January 2020

75-81

1 reference

Europe PubMed Central

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15 January 2020

https://scigraph.springernature.com/pub.10.1007/s00109-010-0687-1

0 references

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationships among age, proinsulin conversion, and beta-cell function in nondiabetic humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MADD, a novel death domain protein that interacts with the type 1 tumor necrosis factor receptor and activates mitogen-activated protein kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic variants at 2q24 are associated with susceptibility to type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Learning from molecular genetics: novel insights arising from the definition of genes for monogenic and type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of liver X receptors inhibits pancreatic islet beta cell proliferation through cell cycle arrest

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of pharmacological liver X receptor activation on hepatic and peripheral insulin sensitivity in lean and ob/ob mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical review: the genetics of type 2 diabetes: a realistic appraisal in 2008.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver X receptor activation stimulates insulin secretion via modulation of glucose and lipid metabolism in pancreatic beta-cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LXRS and FXR: the yin and yang of cholesterol and fat metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis: liver X receptor-mediated lipotoxicity in pancreatic beta-cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genome-wide association study identifies novel risk loci for type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Putative metabolic effects of the liver X receptor (LXR).

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The International HapMap Project

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/21042792

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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