(Q64113627)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30857197%20AND%20SRC:MED&resulttype=core&format=json

28 April 2020

title

Therapeutic Targeting of Stat3 Using Lipopolyplex Nanoparticle-Formulated siRNA in a Syngeneic Orthotopic Mouse Glioma Model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30857197%20AND%20SRC:MED&resulttype=core&format=json

28 April 2020

0 references

0 references

1 reference

1

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28 April 2020

Alexander Ewe

3

1 reference

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28 April 2020

Donat Kögel

9

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28 April 2020

author name string

Ulrike Weirauch

2

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28 April 2020

Anja Uhmann

4

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28 April 2020

Volker Seifert

5

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28 April 2020

Patrick N Harter

7

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28 April 2020

Michel Mittelbronn

6

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28 April 2020

Achim Aigner

8

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28 April 2020

language of work or name

English

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publication date

8 March 2019

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28 April 2020

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28 April 2020

volume

11

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28 April 2020

issue

3

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Creative Commons Attribution 4.0 International

28 April 2020

page(s)

333

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copyright license

start time

8 March 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Induction of Stat3, a signal transducer and transcription factor, in reactive microglia following transient focal cerebral ischaemia.

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12 December 2020

Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice.

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Regulation of matrix metalloproteinase expression in tumor invasion.

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Characterization of Tu-2449, a glioma cell line derived from a spontaneous tumor in GFAP-v-src-transgenic mice: comparison with established murine glioma cell lines.

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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Imaging‐guided convection‐enhanced delivery and gene therapy of glioblastoma

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IL-6 is required for glioma development in a mouse model

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12 December 2020

A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes

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12 December 2020

Lipid encapsulation enables the effective systemic delivery of polyplex plasmid DNA.

1 reference

12 December 2020

Orthotopic transplantation of v-src-expressing glioma cell lines into immunocompetent mice: establishment of a new transplantable in vivo model for malignant glioma

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12 December 2020

Applications of RNA interference: current state and prospects for siRNA-based strategies in vivo

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12 December 2020

Pharmacological inhibition of Bcl-2 family members reactivates TRAIL-induced apoptosis in malignant glioma

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12 December 2020

Signal transducer and activator of transcription-3: a molecular hub for signaling pathways in gliomas

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12 December 2020

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

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12 December 2020

Self-assembling micelle-like nanoparticles based on phospholipid-polyethyleneimine conjugates for systemic gene delivery

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12 December 2020

Stat3 activation is required for the growth of U87 cell-derived tumours in mice

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12 December 2020

Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells

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12 December 2020

STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells

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12 December 2020

Highly efficient eradication of intracranial glioblastoma using Eg5 siRNA combined with HVJ envelope

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Induction of in vivo synthetic lethal RNAi responses to treat glioblastoma

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The transcriptional network for mesenchymal transformation of brain tumours.

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Polyethylenimine/small interfering RNA-mediated knockdown of vascular endothelial growth factor in vivo exerts anti-tumor effects synergistically with Bevacizumab

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Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

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12 December 2020

Liposome-polyethylenimine complexes for enhanced DNA and siRNA delivery

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12 December 2020

Inhibition of the JAK-2/STAT3 signaling pathway impedes the migratory and invasive potential of human glioblastoma cells.

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12 December 2020

STAT3 as a Therapeutic Target for Glioblastoma

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12 December 2020

Dietary curcumin attenuates glioma growth in a syngeneic mouse model by inhibition of the JAK1,2/STAT3 signaling pathway

1 reference

12 December 2020

Regression of recurrent malignant gliomas with convection-enhanced delivery of topotecan

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12 December 2020

The antisense oligonucleotide trabedersen (AP 12009) for the targeted inhibition of TGF-β2.

1 reference

12 December 2020

MicroRNA replacement therapy for miR-145 and miR-33a is efficacious in a model of colon carcinoma

1 reference

12 December 2020

RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo

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12 December 2020

A quantitative spatial proteomics analysis of proteome turnover in human cells

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12 December 2020

Status quo--standard-of-care medical and radiation therapy for glioblastoma.

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12 December 2020

The molecular profile of microglia under the influence of glioma

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12 December 2020

Targeting Stat3 and Smad7 to restore TGF-β cytostatic regulation of tumor cells in vitro and in vivo

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12 December 2020

Signal transducer and activator of transcription 3 promotes angiogenesis and drives malignant progression in glioma

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12 December 2020

Comparing routes of delivery for nanoliposomal irinotecan shows superior anti-tumor activity of local administration in treating intracranial glioblastoma xenografts

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12 December 2020

On-target JAK2/STAT3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells

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12 December 2020

STAT3 silencing inhibits glioma single cell infiltration and tumor growth

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12 December 2020

Polyethylenimines for siRNA and miRNA delivery in vivo

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12 December 2020

Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence

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12 December 2020

Using the molecular classification of glioblastoma to inform personalized treatment

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12 December 2020

STAT3 Activation in Glioblastoma: Biochemical and Therapeutic Implications

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12 December 2020

Storage stability of optimal liposome-polyethylenimine complexes (lipopolyplexes) for DNA or siRNA delivery

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12 December 2020

STAT3 and epithelial-mesenchymal transitions in carcinomas

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12 December 2020

Revisiting STAT3 signalling in cancer: new and unexpected biological functions

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12 December 2020

RNA interference targeting hypoxia-inducible factor 1α via a novel multifunctional surfactant attenuates glioma growth in an intracranial mouse model.

1 reference

12 December 2020

Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 Pathway

1 reference

12 December 2020

Sorafenib Sensitizes Glioma Cells to the BH3 Mimetic ABT-737 by Targeting MCL1 in a STAT3-Dependent Manner

1 reference

12 December 2020

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

1 reference

12 December 2020

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

1 reference

12 December 2020

Cationic Lipid-Coated Polyplexes (Lipopolyplexes) for DNA and Small RNA Delivery

1 reference

12 December 2020

Liposome-polyethylenimine complexes (DPPC-PEI lipopolyplexes) for therapeutic siRNA delivery in vivo

1 reference

12 December 2020

Microparticulate poly(vinyl alcohol) hydrogel formulations for embedding and controlled release of polyethylenimine (PEI)-based nanoparticles.

1 reference

12 December 2020

Interference with the HSF1/HSP70/BAG3 Pathway Primes Glioma Cells to Matrix Detachment and BH3 Mimetic-Induced Apoptosis

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12 December 2020

Protein stabilization improves STAT3 function in autosomal dominant hyper-IgE syndrome.

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12 December 2020

Tumor tissue slice cultures as a platform for analyzing tissue-penetration and biological activities of nanoparticles

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12 December 2020

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12 December 2020

Intranasal drug delivery of small interfering RNA targeting Beclin1 encapsulated with polyethylenimine (PEI) in mouse brain to achieve HIV attenuation

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12 December 2020

STAT3 in cancer: A double edged sword

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12 December 2020

Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression

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12 December 2020

Nanoparticle/siRNA-based therapy strategies in glioma: which nanoparticles, which siRNAs?

1 reference

12 December 2020

Polyethylenimine Nanoparticle-Mediated siRNA Delivery to Reduce α-Synuclein Expression in a Model of Parkinson's Disease

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12 December 2020

Systematic analysis of protein turnover in primary cells.

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12 December 2020

STAT3 Gene Silencing by Aptamer-siRNA Chimera as Selective Therapeutic for Glioblastoma.

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12 December 2020

STAT3, stem cells, cancer stem cells and p63.

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12 December 2020

First-in-human evaluation of the Cleveland Multiport Catheter for convection-enhanced delivery of topotecan in recurrent high-grade glioma: results of pilot trial 1.

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12 December 2020

The critical role that STAT3 plays in glioma-initiating cells: STAT3 addiction in glioma.

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12 December 2020

Identifiers

DOI

10.3390/CANCERS11030333

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30857197%20AND%20SRC:MED&resulttype=core&format=json

28 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30857197%20AND%20SRC:MED&resulttype=core&format=json

28 April 2020

PubMed publication ID

30857197

1 reference