(Q64239253)

English

Autophagy inhibition potentiates the anti-angiogenic property of multikinase inhibitor anlotinib through JAK2/STAT3/VEGFA signaling in non-small cell lung cancer cells

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scholarly article

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Autophagy inhibition potentiates the anti-angiogenic property of multikinase inhibitor anlotinib through JAK2/STAT3/VEGFA signaling in non-small cell lung cancer cells (English)

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angiogenesis inhibitor

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based on heuristic

inferred from title

non-small-cell lung carcinoma

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author name string

Lijun Liang

1

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Kaiyuan Hui

2

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Chenxi Hu

3

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Yixuan Wen

4

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Shikun Yang

5

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Panrong Zhu

6

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Lei Wang

7

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Youyou Xia

8

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Yun Qiao

9

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Wen Sun

10

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Jiayan Fei

11

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Ting Chen

12

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Fenghua Zhao

13

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Baocheng Yang

14

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Xiaodong Jiang

15

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language of work or name

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publication date

12 February 2019

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Journal of Experimental & Clinical Cancer Research

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38

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1

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71

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copyright license

Creative Commons Attribution 4.0 International

12 February 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

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https://scigraph.springernature.com/pub.10.1186/s13046-019-1093-3

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Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis

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https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Another way to die: autophagic programmed cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TOR signaling in growth and metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How to interpret LC3 immunoblotting

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy: process and function

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting autophagy potentiates chemotherapy-induced apoptosis and proliferation inhibition in hepatocarcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of VEGF expression through blockade of Hif1α and STAT3 signalling mediates the anti-angiogenic effect of melatonin in HepG2 liver cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The synergistic effect of everolimus and chloroquine on endothelial cell number reduction is paralleled by increased apoptosis and reduced autophagy occurrence

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chloroquine synergizes sunitinib cytotoxicity via modulating autophagic, apoptotic and angiogenic machineries.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Revisiting STAT3 signalling in cancer: new and unexpected biological functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mTOR: a pharmacologic target for autophagy regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy in malignant transformation and cancer progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safety, pharmacokinetics, and antitumor properties of anlotinib, an oral multi-target tyrosine kinase inhibitor, in patients with advanced refractory solid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic Targeting of Autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WISP-1 positively regulates angiogenesis by controlling VEGF-A expression in human osteosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C-X-C motif chemokine receptor 4 promotes tumor angiogenesis in gastric cancer via activation of JAK2/STAT3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The JAK/STAT3 axis: A comprehensive drug target for solid malignancies

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting autophagy in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Precision Diagnosis and Treatment for Advanced Non-Small-Cell Lung Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple Roles of Autophagy in the Sorafenib Resistance of Hepatocellular Carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of autophagy potentiates the anti-metastasis effect of phenethyl isothiocyanate through JAK2/STAT3 pathway in lung cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy promotes MSC-mediated vascularization in cutaneous wound healing via regulation of VEGF secretion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anlotinib as a third-line therapy in patients with refractory advanced non-small-cell lung cancer: a multicentre, randomised phase II trial (ALTER0302).

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical characterization of anlotinib, a highly potent and selective vascular endothelial growth factor receptor-2 inhibitor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anlotinib inhibits angiogenesis via suppressing the activation of VEGFR2, PDGFRβ and FGFR1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the NRP-1-mediated VEGFR2-independent pathway on radiation sensitivity of non-small cell lung cancer cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ginkgolide K promotes angiogenesis in a middle cerebral artery occlusion mouse model via activating JAK2/STAT3 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Anlotinib as a Third-Line or Further Treatment on Overall Survival of Patients With Advanced Non-Small Cell Lung Cancer: The ALTER 0303 Phase 3 Randomized Clinical Trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anlotinib induces hepatocellular carcinoma apoptosis and inhibits proliferation via Erk and Akt pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anlotinib: a novel multi-targeting tyrosine kinase inhibitor in clinical development

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vandetanib (ZD6474) induces antiangiogenesis through mTOR–HIF-1 alpha–VEGF signaling axis in breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30755242

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S13046-019-1093-3

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Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s13046-019-1093-3

PMC publication ID

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PubMed publication ID

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