(Q64281085)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31116986%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

title

The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template (English)

1 reference

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Simian immunodeficiency virus

27 April 2020

main subject

HIV vaccine

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2

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27 April 2020

Jinsong Zhang

5

1 reference

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27 April 2020

Max Crispin

15

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27 April 2020

20

Dennis R Burton

1 reference

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27 April 2020

19

Andrew B Ward

1 reference

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27 April 2020

17

Barton F Haynes

1 reference

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27 April 2020

16

Beatrice H Hahn

1 reference

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27 April 2020

14

Ian A Wilson

1 reference

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27 April 2020

10

Matthias Pauthner

1 reference

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27 April 2020

Hilary Bouton-Verville

12

object named as

Hilary Bouton-Verville

1 reference

27 April 2020

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18

Laurent Verkoczy

1 reference

27 April 2020

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Raiees Andrabi

1

1 reference

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27 April 2020

Joel D Allen

3

1 reference

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27 April 2020

Ge Song

4

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27 April 2020

Natalia de Val

6

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27 April 2020

Gavin Gegg

7

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27 April 2020

Katelyn Porter

8

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27 April 2020

Ching-Yao Su

9

1 reference

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27 April 2020

Amanda Newman

11

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27 April 2020

Fernando Garces

13

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27 April 2020

language of work or name

English

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publication date

1 May 2019

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27 April 2020

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27 April 2020

volume

27

1 reference

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27 April 2020

issue

8

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27 April 2020

page(s)

2426-2441.e6

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Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes

27 April 2020

cites work

1 reference

12 December 2020

Timing the ancestor of the HIV-1 pandemic strains

1 reference

12 December 2020

PHENIX: building new software for automated crystallographic structure determination

1 reference

12 December 2020

Topology representing network enables highly accurate classification of protein images taken by cryo electron-microscope without masking.

1 reference

12 December 2020

Structure of the uncleaved human H1 hemagglutinin from the extinct 1918 influenza virus

1 reference

12 December 2020

Tracking global patterns of N-linked glycosylation site variation in highly variable viral glycoproteins: HIV, SIV, and HCV envelopes and influenza hemagglutinin

1 reference

12 December 2020

UCSF Chimera--a visualization system for exploratory research and analysis

1 reference

12 December 2020

Coot: model-building tools for molecular graphics

1 reference

12 December 2020

Edward Jenner and the history of smallpox and vaccination

1 reference

12 December 2020

Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

1 reference

12 December 2020

Comparative protein structure modeling using Modeller

1 reference

12 December 2020

Evaluating neutralizing antibodies against HIV, SIV, and SHIV in luciferase reporter gene assays

1 reference

12 December 2020

IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis

1 reference

12 December 2020

Application of negative ion MS/MS to the identification of N-glycans released from carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1).

1 reference

12 December 2020

Direct evidence of extensive diversity of HIV-1 in Kinshasa by 1960

1 reference

12 December 2020

DoG Picker and TiltPicker: software tools to facilitate particle selection in single particle electron microscopy

1 reference

12 December 2020

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

1 reference

12 December 2020

Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: implications for evasion of immune responses and design of vaccine immunogens

1 reference

12 December 2020

Tiered categorization of a diverse panel of HIV-1 Env pseudoviruses for assessment of neutralizing antibodies

1 reference

12 December 2020

Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance

1 reference

12 December 2020

MolProbity: all-atom structure validation for macromolecular crystallography

1 reference

12 December 2020

Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

1 reference

12 December 2020

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

1 reference

12 December 2020

Potent and broad neutralization of HIV-1 subtype C by plasma antibodies targeting a quaternary epitope including residues in the V2 loop

1 reference

12 December 2020

Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

1 reference

12 December 2020

Broad neutralization coverage of HIV by multiple highly potent antibodies

1 reference

12 December 2020

The glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.

1 reference

12 December 2020

Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls

1 reference

12 December 2020

A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield

1 reference

12 December 2020

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

1 reference

12 December 2020

Origins of HIV and the AIDS pandemic

1 reference

12 December 2020

B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study

1 reference

12 December 2020

Human peripheral blood antibodies with long HCDR3s are established primarily at original recombination using a limited subset of germline genes

1 reference

12 December 2020

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization

1 reference

12 December 2020

RELION: implementation of a Bayesian approach to cryo-EM structure determination

1 reference

12 December 2020

High-affinity IgG antibodies develop naturally in Ig-knockout rats carrying germline human IgH/Igκ/Igλ loci bearing the rat CH region

1 reference

12 December 2020

Cross-group neutralization of HIV-1 and evidence for conservation of the PG9/PG16 epitopes within divergent groups

1 reference

12 December 2020

Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9.

1 reference

12 December 2020

Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies

1 reference

12 December 2020

Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors

1 reference

12 December 2020

Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization

1 reference

12 December 2020

Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

1 reference

12 December 2020

Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization

1 reference

12 December 2020

Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120

1 reference

12 December 2020

Structural basis for diverse N-glycan recognition by HIV-1–neutralizing V1–V2–directed antibody PG16

1 reference

12 December 2020

Common tolerance mechanisms, but distinct cross-reactivities associated with gp41 and lipids, limit production of HIV-1 broad neutralizing antibodies 2F5 and 4E10

1 reference

12 December 2020

A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

1 reference

12 December 2020

Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer

1 reference

12 December 2020

Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer

1 reference

12 December 2020

Viral escape from HIV-1 neutralizing antibodies drives increased plasma neutralization breadth through sequential recognition of multiple epitopes and immunotypes

1 reference

12 December 2020

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

1 reference

12 December 2020

Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery.

1 reference

12 December 2020

Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimers

1 reference

12 December 2020

Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers

1 reference

12 December 2020

Promiscuous glycan site recognition by antibodies to the high-mannose patch of gp120 broadens neutralization of HIV.

1 reference

12 December 2020

Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies

1 reference

12 December 2020

Structural evolution of glycan recognition by a family of potent HIV antibodies

1 reference

12 December 2020

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

1 reference

12 December 2020

Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

1 reference

12 December 2020

A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene

1 reference

12 December 2020

Manipulating the selection forces during affinity maturation to generate cross-reactive HIV antibodies

1 reference

12 December 2020

Atomic-accuracy models from 4.5-Å cryo-electron microscopy data with density-guided iterative local refinement

1 reference

12 December 2020

Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design

1 reference

12 December 2020

Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas

1 reference

12 December 2020

Cell- and Protein-Directed Glycosylation of Native Cleaved HIV-1 Envelope

1 reference

12 December 2020

HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers

1 reference

12 December 2020

HIV-1 VACCINES. Priming a broadly neutralizing antibody response to HIV-1 using a germline-targeting immunogen.

1 reference

12 December 2020

Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice

1 reference

12 December 2020

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

1 reference

12 December 2020

EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy.

1 reference

12 December 2020

Model Building and Refinement of a Natively Glycosylated HIV-1 Env Protein by High-Resolution Cryoelectron Microscopy

1 reference

12 December 2020

V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1

1 reference

12 December 2020

Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies

1 reference

12 December 2020

Privateer: software for the conformational validation of carbohydrate structures.

1 reference

12 December 2020

Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design

1 reference

12 December 2020

Gctf: Real-time CTF determination and correction

1 reference

12 December 2020

Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.

1 reference

12 December 2020

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

1 reference

12 December 2020

Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort

1 reference

12 December 2020

Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice.

1 reference

12 December 2020

Visualizing antibody affinity maturation in germinal centers

1 reference

12 December 2020

Cryo-EM structure of a native, fully glycosylated, cleaved HIV-1 envelope trimer

1 reference

12 December 2020

Composition and Antigenic Effects of Individual Glycan Sites of a Trimeric HIV-1 Envelope Glycoprotein

1 reference

12 December 2020

A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans.

1 reference

12 December 2020

Structures of Ebola virus GP and sGP in complex with therapeutic antibodies

1 reference

12 December 2020

Mapping the complete glycoproteome of virion-derived HIV-1 gp120 provides insights into broadly neutralizing antibody binding

1 reference

12 December 2020

Priming HIV-1 broadly neutralizing antibody precursors in human Ig loci transgenic mice

1 reference

12 December 2020

Sequential Immunization Elicits Broadly Neutralizing Anti-HIV-1 Antibodies in Ig Knockin Mice

1 reference

12 December 2020

Tailored Immunogens Direct Affinity Maturation toward HIV Neutralizing Antibodies

1 reference

12 December 2020

Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires

1 reference

12 December 2020

Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site

1 reference

12 December 2020

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

1 reference

12 December 2020

Molecular Architecture of the Cleavage-Dependent Mannose Patch on a Soluble HIV-1 Envelope Glycoprotein Trimer

1 reference

12 December 2020

Progress toward active or passive HIV-1 vaccination

1 reference

12 December 2020

The quest for an antibody-based HIV vaccine

1 reference

12 December 2020

Ontogeny-based immunogens for the induction of V2-directed HIV broadly neutralizing antibodies

1 reference

12 December 2020

Tfh cells and HIV bnAbs, an immunodominance model of the HIV neutralizing antibody generation problem

1 reference

12 December 2020

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

1 reference

12 December 2020

A Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure

1 reference

12 December 2020

Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike

1 reference

12 December 2020

Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows

1 reference

12 December 2020

Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.

1 reference

12 December 2020

Glycans Function as Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development

1 reference

12 December 2020

Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model

1 reference

12 December 2020

HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage

1 reference

12 December 2020

Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations

1 reference

12 December 2020

Vaccine Induction of Heterologous Tier 2 HIV-1 Neutralizing Antibodies in Animal Models

1 reference

12 December 2020

Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens

1 reference

12 December 2020

Anti-HIV-1 B cell responses are dependent on B cell precursor frequency and antigen-binding affinity.

1 reference

12 December 2020

Strategies for a multi-stage neutralizing antibody-based HIV vaccine

1 reference

12 December 2020

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

1 reference

12 December 2020

10.1016/J.CELREP.2019.04.082

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31116986%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31116986%20AND%20SRC:MED&resulttype=core&format=json

27 April 2020

PubMed publication ID

31116986

1 reference