(Q64378704)

12 December 2020

Eradication of disseminated adenovirus infection in a pediatric hematopoietic stem cell transplantation recipient using the novel antiviral agent CMX001

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12 December 2020

Directed adenovirus evolution using engineered mutator viral polymerases

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12 December 2020

Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis

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12 December 2020

Synthesis, metabolic stability and antiviral evaluation of various alkoxyalkyl esters of cidofovir and 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]adenine

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12 December 2020

Using the whole-genome sequence to characterize and name human adenoviruses

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12 December 2020

Toward an integrated human adenovirus designation system that utilizes molecular and serological data and serves both clinical and fundamental virology

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12 December 2020

Identification of conserved residues contributing to the activities of adenovirus DNA polymerase

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12 December 2020

An aspartic acid residue in TPR-1, a specific region of protein-priming DNA polymerases, is required for the functional interaction with primer terminal protein

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12 December 2020

Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69.

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12 December 2020

3'-->5' exonuclease active site of phi 29 DNA polymerase. Evidence favoring a metal ion-assisted reaction mechanism

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12 December 2020

Crystallization and Preliminary X-Ray Crystallographic Studies on the Adenovirus ssDNA Binding Protein in Complex with ssDNA

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12 December 2020

Primer-terminus stabilization at the 3'-5' exonuclease active site of phi29 DNA polymerase. Involvement of two amino acid residues highly conserved in proofreading DNA polymerases

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12 December 2020

In vitro protein-primed initiation of pneumococcal phage Cp-1 DNA replication occurs at the third 3' nucleotide of the linear template: a stepwise sliding-back mechanism

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12 December 2020

Herpes simplex virus type 1 DNA polymerase. Mutational analysis of the 3'-5'-exonuclease domain

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12 December 2020

Functional characterization of the genes coding for the terminal protein and DNA polymerase from bacteriophage GA-1. Evidence for a sliding-back mechanism during protein-primed GA-1 DNA replication

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12 December 2020

Functional consequences and exonuclease kinetic parameters of point mutations in bacteriophage T4 DNA polymerase

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12 December 2020

The Oct-1 POU homeodomain stabilizes the adenovirus preinitiation complex via a direct interaction with the priming protein and is displaced when the replication fork passes

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12 December 2020

Dissociation of the protein primer and DNA polymerase after initiation of adenovirus DNA replication

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12 December 2020

Effects of mutations in the Exo III motif of the herpes simplex virus DNA polymerase gene on enzyme activities, viral replication, and replication fidelity.

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12 December 2020

Evolution of viral DNA-dependent DNA polymerases

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12 December 2020

Mutational analysis of phi29 DNA polymerase residues acting as ssDNA ligands for 3'-5' exonucleolysis

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12 December 2020

Chromatin structure of adenovirus DNA throughout infection

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12 December 2020

Immune control of an SIV challenge by a T-cell-based vaccine in rhesus monkeys

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12 December 2020

Adenovirus: an increasingly important pathogen in paediatric bone marrow transplant patients.

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12 December 2020

The impact of adenovirus infection on the immunocompromised host

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12 December 2020

Extensive cross-reactivity of CD4+ adenovirus-specific T cells: implications for immunotherapy and gene therapy.

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12 December 2020

Adenovirus DNA Replication

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12 December 2020

Adenovirus DNA replication: protein priming, jumping back and the role of the DNA binding protein DBP.

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12 December 2020

Adenovirus infection in hematopoietic stem cell transplantation: effect of ganciclovir and impact on survival

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12 December 2020

Bending of adenovirus origin DNA by nuclear factor I as shown by scanning force microscopy is required for optimal DNA replication

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12 December 2020

Treatment of adenovirus infections in the immunocompromised host

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12 December 2020

Structure of the linkage between adenovirus DNA and the 55,000 molecular weight terminal protein

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12 December 2020

Adenovirus terminal protein precursor. Partial amino acid sequence and the site of covalent linkage to virus DNA.

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12 December 2020

Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases

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12 December 2020

Highly efficient DNA synthesis by the phage phi 29 DNA polymerase. Symmetrical mode of DNA replication

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12 December 2020

A conserved 3'----5' exonuclease active site in prokaryotic and eukaryotic DNA polymerases

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12 December 2020

An attempt to unify the structure of polymerases

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12 December 2020

Mechanism of DNA replication in eukaryotic cells: cellular host factors stimulating adenovirus DNA replication.

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12 December 2020

Insights into strand displacement and processivity from the crystal structure of the protein-primed DNA polymerase of bacteriophage phi29.

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12 December 2020

NFI and Oct-1 bend the Ad5 origin in the same direction leading to optimal DNA replication

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12 December 2020

Prospects for adenovirus antivirals

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12 December 2020

Adenovirus infection in children after allogeneic stem cell transplantation: diagnosis, treatment and immunity.

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12 December 2020

A specific subdomain in phi29 DNA polymerase confers both processivity and strand-displacement capacity

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12 December 2020

Recent lessons in gene expression, cell cycle control, and cell biology from adenovirus

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12 December 2020

Relaxed template specificity in fowl adenovirus 1 DNA replication initiation

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12 December 2020

Adenoviral infections in hematopoietic stem cell transplantation

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12 December 2020

The phi29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition

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12 December 2020

Current strategies and future directions for eluding adenoviral vector immunity

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12 December 2020

Safe adoptive transfer of virus-specific T-cell immunity for the treatment of systemic adenovirus infection after allogeneic stem cell transplantation

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12 December 2020

Human CD4+ T cells stimulated by conserved adenovirus 5 hexon peptides recognize cells infected with different species of human adenovirus

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12 December 2020

History of oncolytic viruses: genesis to genetic engineering

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12 December 2020

Invasive adenoviral infections in T-cell-depleted allogeneic hematopoietic stem cell transplantation: high mortality in the era of cidofovir

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12 December 2020

Structures of phi29 DNA polymerase complexed with substrate: the mechanism of translocation in B-family polymerases

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12 December 2020

Immune response to helper dependent adenoviral mediated liver gene therapy: challenges and prospects.

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12 December 2020

Accelerated evolution of maribavir resistance in a cytomegalovirus exonuclease domain II mutant

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12 December 2020

Hexadecyloxypropyl-cidofovir, CMX001, prevents adenovirus-induced mortality in a permissive, immunosuppressed animal model

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12 December 2020

Clinical features and treatment of adenovirus infections

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12 December 2020

Small DNA tumour viruses and their contributions to our understanding of transcription control

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12 December 2020

Differential susceptibility of adenovirus clinical isolates to cidofovir and ribavirin is not related to species alone.

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12 December 2020

p53 and E2f: partners in life and death

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12 December 2020

The (I/Y)XGG motif of adenovirus DNA polymerase affects template DNA binding and the transition from initiation to elongation

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12 December 2020

Molecular architecture of adenovirus DNA polymerase and location of the protein primer

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12 December 2020

Sequence changes in the human adenovirus type 5 DNA polymerase associated with resistance to the broad spectrum antiviral cidofovir

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12 December 2020

Adenovirus type 5 DNA binding protein stimulates binding of DNA polymerase to the replication origin

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12 December 2020

Structural and functional analysis of temperature-sensitive mutants of the phage phi 29 DNA polymerase

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12 December 2020

Mutagenesis of conserved region I in the DNA polymerase from human adenovirus serotype 2.

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12 December 2020

Protein-priming of DNA replication

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12 December 2020

Mutations in two cysteine-histidine-rich clusters in adenovirus type 2 DNA polymerase affect DNA binding

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12 December 2020

Site-directed mutagenesis at the Exo III motif of phi 29 DNA polymerase; overlapping structural domains for the 3'-5' exonuclease and strand-displacement activities

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12 December 2020

Initiation of phi 29 DNA replication occurs at the second 3' nucleotide of the linear template: a sliding-back mechanism for protein-primed DNA replication.

1 reference

12 December 2020

In vitro replication of bacteriophage PRD1 DNA. Characterization of the protein-primed initiation site

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12 December 2020

A precursor terminal protein-trinucleotide intermediate during initiation of adenovirus DNA replication: regeneration of molecular ends in vitro by a jumping back mechanism

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12 December 2020