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[DNA-dependent protein kinase (DNA-PK), a key enzyme in the re-ligation of double-stranded DNA breaks]
scientific article published on 01 July 1999
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Europe PubMed Central
PubMed publication ID
10486539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10486539%20AND%20SRC:MED&resulttype=core&format=json
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31 October 2019
review article
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title
[DNA-dependent protein kinase (DNA-PK), a key enzyme in the re-ligation of double-stranded DNA breaks]
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10486539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10486539%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
author name string
Hennequin C
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1
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Europe PubMed Central
PubMed publication ID
10486539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10486539%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
Giocanti N
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2
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Europe PubMed Central
PubMed publication ID
10486539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10486539%20AND%20SRC:MED&resulttype=core&format=json
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31 October 2019
Averbeck D
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3
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Europe PubMed Central
PubMed publication ID
10486539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10486539%20AND%20SRC:MED&resulttype=core&format=json
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31 October 2019
Favaudon V
series ordinal
4
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Europe PubMed Central
PubMed publication ID
10486539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10486539%20AND%20SRC:MED&resulttype=core&format=json
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31 October 2019
publication date
1 July 1999
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Europe PubMed Central
PubMed publication ID
10486539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10486539%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
published in
Cancer Radiothérapie
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Europe PubMed Central
PubMed publication ID
10486539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10486539%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
volume
3
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Europe PubMed Central
PubMed publication ID
10486539
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10486539%20AND%20SRC:MED&resulttype=core&format=json
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31 October 2019
issue
4
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Europe PubMed Central
PubMed publication ID
10486539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10486539%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
page(s)
289-295
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10486539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10486539%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
cites work
Double-strand break repair deficiency and radiation sensitivity in BRCA2 mutant cancer cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
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inferred from DOI database lookup
DNA damage and the DNA-activated protein kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
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Enhanced phosphorylation of p53 by ATM in response to DNA damage
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
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inferred from DOI database lookup
scid cells are deficient in Ku and replication protein A phosphorylation by the DNA-dependent protein kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
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inferred from DOI database lookup
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
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inferred from DOI database lookup
DNA-dependent ATPase from HeLa cells is related to human Ku autoantigen
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
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The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
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inferred from DOI database lookup
X-ray--induced breakage and rejoining of human interphase chromosomes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
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inferred from DOI database lookup
DNA end-joining: from yeast to man
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
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inferred from DOI database lookup
Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
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inferred from DOI database lookup
Induction and repair of chromosome aberrations in scid cells measured by premature chromosome condensation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
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inferred from DOI database lookup
Review of repair kinetics for DNA damage induced in eukaryotic cells in vitro by ionizing radiation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Implication of DNA-dependent protein kinase in an early, essential, local phosphorylation event during end-joining of DNA double-strand breaks in vitro
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
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A phosphatidylinositol 3-kinase inhibitor wortmannin induces radioresistant DNA synthesis and sensitizes cells to bleomycin and ionizing radiation
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
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Differential etoposide sensitivity of cells deficient in the Ku and DNA-PKcs components of the DNA-dependent protein kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
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Replication errors: cha(lle)nging the genome
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
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inferred from DOI database lookup
Functional interaction between DNA-PK and c-Abl in response to DNA damage
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-dependent protein kinase: a potent inhibitor of transcription by RNA polymerase I
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Relationship of the ataxia-telangiectasia protein ATM to phosphoinositide 3-kinase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The XRCC4 gene product is a target for and interacts with the DNA-dependent protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human DNA-activated protein kinase phosphorylates serines 15 and 37 in the amino-terminal transactivation domain of human p53.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
based on heuristic
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Tying loose ends: roles of Ku and DNA-dependent protein kinase in the repair of double-strand breaks
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular cloning and analysis of Schizosaccharomyces pombe rad9, a gene involved in DNA repair and mutagenesis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The DNA-dependent protein kinase: a matter of life and (cell) death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Strand-specific mismatch repair in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the p53 and SCID genes cooperate in tumorigenesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for Ku80 in growth and immunoglobulin V(D)J recombination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wortmannin inhibits repair of DNA double-strand breaks in irradiated normal human cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conservation of eukaryotic DNA repair mechanisms.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure and function of mammalian DNA ligases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of DNA-dependent protein kinase inhibition by cis-diamminedichloroplatinum(II)-damaged DNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA-dependent protein kinase acts upstream of p53 in response to DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA repair in eukaryotes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of DNA-dependent protein kinase with DNA and with Ku: biochemical and atomic-force microscopy studies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian mutants defective in the response to ionizing radiation-induced DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1278-3218%2899%2980070-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1278-3218(99)80070-5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10486539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10486539%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
PubMed publication ID
10486539
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10486539
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10486539%20AND%20SRC:MED&resulttype=core&format=json
retrieved
31 October 2019
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