(Q64904301)

30 June 2019

title

Loss of Sarm1 does not suppress motor neuron degeneration in the SOD1G93A mouse model of amyotrophic lateral sclerosis. (English)

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30 June 2019

amyotrophic lateral sclerosis

main subject

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1

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30 June 2019

Robert H Brown

7

object named as

Robert H Brown

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30 June 2019

author name string

Elizabeth A Lewis

2

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30 June 2019

Jeannette M Osterloh

3

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30 June 2019

Alexandra Weiss

4

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30 June 2019

Johnny S Salameh

5

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30 June 2019

Jake Metterville

6

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30 June 2019

Marc R Freeman

8

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30 June 2019

publication date

1 November 2018

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30 June 2019

published in

Human Molecular Genetics

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30 June 2019

volume

27

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30 June 2019

issue

21

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30 June 2019

page(s)

3761-3771

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30 June 2019

Creative Commons Attribution 4.0 International

copyright license

start time

14 July 2018

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6196650/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Electrophysiological estimation of the number of motor units within a human muscle

1 reference

12 December 2020

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

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12 December 2020

Comparison of incremental with multipoint MUNE methods in transgenic ALS mice

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12 December 2020

The WldS protein protects against axonal degeneration: a model of gene therapy for peripheral neuropathy

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Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.

1 reference

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Absence of Wallerian Degeneration does not Hinder Regeneration in Peripheral Nerve

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12 December 2020

WldS mice are resistant to paclitaxel (taxol) neuropathy

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12 December 2020

Inhibiting axon degeneration and synapse loss attenuates apoptosis and disease progression in a mouse model of motoneuron disease

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12 December 2020

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

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12 December 2020

Wlds-mediated protection of dopaminergic fibers in an animal model of Parkinson disease

1 reference

12 December 2020

The neuroprotective factor Wlds does not attenuate mutant SOD1-mediated motor neuron disease

1 reference

12 December 2020

The slow Wallerian degeneration gene, WldS, inhibits axonal spheroid pathology in gracile axonal dystrophy mice.

1 reference

12 December 2020

The effect of peripheral nerve injury on disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

1 reference

12 December 2020

The WldS gene modestly prolongs survival in the SOD1G93A fALS mouse

1 reference

12 December 2020

Wld(S) mice are protected against the Parkinsonian mimetic MPTP.

1 reference

12 December 2020

Motor unit number estimation predicts disease onset and survival in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

12 December 2020

Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS

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12 December 2020

The WldS gene delays axonal but not somatic degeneration in a rat glaucoma model

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12 December 2020

Nicotinamide mononucleotide adenylyltransferase expression in mitochondrial matrix delays Wallerian degeneration.

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Wallerian degeneration, wld(s), and nmnat

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Multipoint incremental motor unit number estimation as an outcome measure in ALS.

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Targeting of pro-apoptotic TLR adaptor SARM to mitochondria: definition of the critical region and residues in the signal sequence

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WldS prevents axon degeneration through increased mitochondrial flux and enhanced mitochondrial Ca2+ buffering

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12 December 2020

Retinal ganglion cell survival and axon regeneration in WldS transgenic rats after optic nerve crush and lens injury

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12 December 2020

dSarm/Sarm1 is required for activation of an injury-induced axon death pathway

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12 December 2020

Mutant SOD1G93A triggers mitochondrial fragmentation in spinal cord motor neurons: neuroprotection by SIRT3 and PGC-1α.

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12 December 2020

The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein

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The Phr1 ubiquitin ligase promotes injury-induced axon self-destruction

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12 December 2020

Sarm1-mediated axon degeneration requires both SAM and TIR interactions

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12 December 2020

A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis

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12 December 2020

Rapid in vivo forward genetic approach for identifying axon death genes in Drosophila

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Mitochondrial dysfunction induces Sarm1-dependent cell death in sensory neurons

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Emerging mechanisms of molecular pathology in ALS

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Neurodegeneration in C. elegans models of ALS requires TIR-1/Sarm1 immune pathway activation in neurons.

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Age-Dependent TDP-43-Mediated Motor Neuron Degeneration Requires GSK3, hat-trick, and xmas-2.

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Attenuated traumatic axonal injury and improved functional outcome after traumatic brain injury in mice lacking Sarm1.

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Enhancing NAD+ Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1).

1 reference

12 December 2020

Axonal degeneration, distal collateral branching and neuromuscular junction architecture alterations occur prior to symptom onset in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

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12 December 2020

Prevention of vincristine-induced peripheral neuropathy by genetic deletion of SARM1 in mice.

1 reference

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Axon Death Pathways Converge on Axundead to Promote Functional and Structural Axon Disassembly.

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Impaired Mitophagy Plays a Role in Denervation of Neuromuscular Junctions in ALS Mice

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Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders

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Sarm1 Deletion, but Not WldS, Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy

1 reference

12 December 2020

Experiments on the Section of the Glosso-Pharyngeal and Hypoglossal Nerves of the Frog, and Observations of the Alterations Produced Thereby in the Structure of Their Primitive Fibres

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDY260

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30 June 2019

PMC publication ID

6196650

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30 June 2019

PubMed publication ID

30010873

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30 June 2019