(Q42377336)

28 October 2017

Sarm1 Deletion, but Not WldS, Confers Lifelong Rescue in a Mouse Model of Severe Axonopathy (English)

1 reference

28 October 2017

Jonathan Gilley

1

1 reference

PMC publication ID

5640801

28 October 2017

Richard R Ribchester

series ordinal

2

1 reference

PMC publication ID

5640801

28 October 2017

Michael P Coleman

series ordinal

3

1 reference

28 October 2017

1 October 2017

1 reference

28 October 2017

1 reference

28 October 2017

21

1 reference

28 October 2017

1

1 reference

28 October 2017

10-16

1 reference

PMC publication ID

5640801

describes a project that uses

28 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5640801/fullTextXML

inferred from PubMed Central ID database lookup

cites work

NMN Deamidase Delays Wallerian Degeneration and Rescues Axonal Defects Caused by NMNAT2 Deficiency In Vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

NMNAT2:HSP90 Complex Mediates Proteostasis in Proteinopathies.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

Wallerian Degeneration Is Executed by an NMN-SARM1-Dependent Late Ca(2+) Influx but Only Modestly Influenced by Mitochondria.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

SARM1 activation triggers axon degeneration locally via NAD⁺ destruction

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

Absence of SARM1 rescues development and survival of NMNAT2-deficient axons

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

Wallerian degeneration: an emerging axon death pathway linking injury and disease

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

A genome-wide association meta-analysis identifies a novel locus at 17q11.2 associated with sporadic amyotrophic lateral sclerosis

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

Sarm1-mediated axon degeneration requires both SAM and TIR interactions

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

Mutations in a P-type ATPase gene cause axonal degeneration

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

dSarm/Sarm1 is required for activation of an injury-induced axon death pathway

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

Chemical genetic-mediated spatial regulation of protein expression in neurons reveals an axonal function for wld(s).

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

Attenuation of age-related changes in mouse neuromuscular synapses by caloric restriction and exercise

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration.

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

Rescue of peripheral and CNS axon defects in mice lacking NMNAT2.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

The slow Wallerian degeneration gene, WldS, inhibits axonal spheroid pathology in gracile axonal dystrophy mice.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

The neuroprotective factor Wlds does not attenuate mutant SOD1-mediated motor neuron disease

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5640801

Differential protection of neuromuscular sensory and motor axons and their endings in Wld(S) mutant mice

16 August 2018

1 reference

12 December 2020

Fast motor axon loss in SMARD1 does not correspond to morphological and functional alterations of the NMJ

1 reference

12 December 2020

The WldS gene modestly prolongs survival in the SOD1G93A fALS mouse

1 reference

12 December 2020

Age-dependent synapse withdrawal at axotomised neuromuscular junctions in Wld(s) mutant and Ube4b/Nmnat transgenic mice

1 reference

12 December 2020

10.1016/J.CELREP.2017.09.027

Identifiers

DOI

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/v4dobzkr5vg7lbz5f7xiti5enq

30 July 2022

release_v4dobzkr5vg7lbz5f7xiti5enq

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/v4dobzkr5vg7lbz5f7xiti5enq

30 July 2022

https://api.fatcat.wiki/v0/release/v4dobzkr5vg7lbz5f7xiti5enq

1 reference

30 July 2022

https://api.fatcat.wiki/v0/release/v4dobzkr5vg7lbz5f7xiti5enq

PubMed publication ID

1 reference

30 July 2022