(Q47581945)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28334607%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

The SARM1 Toll/Interleukin-1 Receptor Domain Possesses Intrinsic NAD+ Cleavage Activity that Promotes Pathological Axonal Degeneration (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28334607%20AND%20SRC:MED&resulttype=core&format=json

Sterile alpha and TIR motif containing 1

13 March 2020

main subject

1 reference

positive regulation of neuron death

1 reference

Sterile alpha and HEAT/Armadillo motif containing 1

1 reference

Sterile alpha and TIR motif containing 1

1 reference

Sterile alpha and Armadillo motif Dmel_CG43119

1 reference

author

Jeffrey Milbrandt

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28334607%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

author name string

Kow Essuman

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28334607%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Daniel W Summers

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28334607%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Yo Sasaki

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28334607%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Xianrong Mao

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28334607%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Aaron DiAntonio

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28334607%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

language of work or name

English

0 references

publication date

1 March 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28334607%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28334607%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

volume

93

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28334607%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28334607%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

page(s)

1334-1343.e5

1 reference

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describes a project that uses

13 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6284238/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Absence of Wallerian Degeneration does not Hinder Regeneration in Peripheral Nerve

1 reference

12 December 2020

TIR domain-containing adaptor SARM is a late addition to the ongoing microbe-host dialog

1 reference

12 December 2020

Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search

1 reference

12 December 2020

Comparative genomic analyses reveal a vast, novel network of nucleotide-centric systems in biological conflicts, immunity and signaling

1 reference

12 December 2020

Regulation of calcium signalling by adenine-based second messengers

1 reference

12 December 2020

Crystal structures of nucleoside 2-deoxyribosyltransferase in native and ligand-bound forms reveal architecture of the active site

1 reference

12 December 2020

Characterization of Streptococcus pyogenes beta-NAD+ glycohydrolase: re-evaluation of enzymatic properties associated with pathogenesis

1 reference

12 December 2020

The Phyre2 web portal for protein modeling, prediction and analysis

1 reference

12 December 2020

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

1 reference

12 December 2020

Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism

1 reference

12 December 2020

Prevention of vincristine-induced peripheral neuropathy by genetic deletion of SARM1 in mice.

1 reference

12 December 2020

NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.

1 reference

12 December 2020

New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs

1 reference

12 December 2020

Attenuated traumatic axonal injury and improved functional outcome after traumatic brain injury in mice lacking Sarm1.

1 reference

12 December 2020

Sarm1-mediated axon degeneration requires both SAM and TIR interactions

1 reference

12 December 2020

Cell-free translation reconstituted with purified components

1 reference

12 December 2020

Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons

1 reference

12 December 2020

Wallerian degeneration of injured axons and synapses is delayed by a Ube4b/Nmnat chimeric gene.

1 reference

12 December 2020

dSarm/Sarm1 is required for activation of an injury-induced axon death pathway

1 reference

12 December 2020

Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide

1 reference

12 December 2020

Pathological axonal death through a MAPK cascade that triggers a local energy deficit

1 reference

12 December 2020

Enhanced FASP (eFASP) to increase proteome coverage and sample recovery for quantitative proteomic experiments

1 reference

12 December 2020

Deep amino acid sequencing of native brain GABAA receptors using high-resolution mass spectrometry

1 reference

12 December 2020

The many faces of SAM

1 reference

12 December 2020

Calcium release from intra-axonal endoplasmic reticulum leads to axon degeneration through mitochondrial dysfunction

1 reference

12 December 2020

Axonal degeneration in motor neuron disease

1 reference

12 December 2020

Armadillo-repeat protein functions: questions for little creatures

1 reference

12 December 2020

SARM1-specific motifs in the TIR domain enable NAD+ loss and regulate injury-induced SARM1 activation

1 reference

12 December 2020

A dual leucine kinase-dependent axon self-destruction program promotes Wallerian degeneration

1 reference

12 December 2020

Reversal of the Substrate Specificity of CMP N -Glycosidase to dCMP

1 reference

12 December 2020

Structural Basis for Enzymatic Evolution from a Dedicated ADP-ribosyl Cyclase to a Multifunctional NAD Hydrolase

1 reference

12 December 2020

MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.

1 reference

12 December 2020

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

1 reference

12 December 2020

Universal sample preparation method for proteome analysis

1 reference

12 December 2020

The history of Toll-like receptors - redefining innate immunity.

1 reference

12 December 2020

The Highwire ubiquitin ligase promotes axonal degeneration by tuning levels of Nmnat protein

1 reference

12 December 2020

Human CD38 is an authentic NAD(P)+ glycohydrolase

1 reference

12 December 2020

A statistical model for identifying proteins by tandem mass spectrometry

1 reference

12 December 2020

Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme

1 reference

12 December 2020

SARM1 activation triggers axon degeneration locally via NAD⁺ destruction

1 reference

12 December 2020

Is Axonal Degeneration a Key Early Event in Parkinson's Disease?

1 reference

12 December 2020

The HHpred interactive server for protein homology detection and structure prediction

1 reference

12 December 2020

NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

1 reference

12 December 2020

A local mechanism mediates NAD-dependent protection of axon degeneration

1 reference

12 December 2020

10.1016/J.NEURON.2017.02.022

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28334607%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28334607%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

PubMed publication ID

28334607

1 reference