(Q64924726)

1 July 2019

title

Therapeutic cancer vaccines. (English)

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1 July 2019

author

Benedetto Farsaci

7

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1 July 2019

Jeffrey Schlom

1

object named as

Jeffrey Schlom

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1 July 2019

James L. Gulley

10

object named as

James L Gulley

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1 July 2019

author name string

James W Hodge

2

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1 July 2019

Claudia Palena

3

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1 July 2019

Kwong-Yok Tsang

4

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1 July 2019

Caroline Jochems

5

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1 July 2019

John W Greiner

6

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1 July 2019

Ravi A Madan

8

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1 July 2019

Christopher R Heery

9

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1 July 2019

publication date

1 January 2014

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1 July 2019

Advances in Cancer Research

published in

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1 July 2019

volume

121

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1 July 2019

page(s)

67-124

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1 July 2019

The use of combination vaccinia vaccines and dual-gene vaccinia vaccines to enhance antigen-specific T-cell immunity via T-cell costimulation

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Natural history of progression after PSA elevation following radical prostatectomy

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Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anti-carcinoembryonic antigen immune responses

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High-avidity CTL exploit two complementary mechanisms to provide better protection against viral infection than low-avidity CTL.

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The influence of granulocyte macrophage colony-stimulating factor and prior chemotherapy on the immunological response to a vaccine (ALVAC-CEA B7.1) in patients with metastatic carcinoma

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Synergy of vaccine strategies to amplify antigen-specific immune responses and antitumor effects

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Immune and clinical responses in patients with metastatic melanoma to CD34(+) progenitor-derived dendritic cell vaccine

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Trends in long-term survival following liver resection for hepatic colorectal metastases

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CTLA-4: new insights into its biological function and use in tumor immunotherapy

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Epithelial-mesenchymal transitions in tumour progression

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Vector-based vaccine/cytokine combination therapy to enhance induction of immune responses to a self-antigen and antitumor activity

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12 December 2020

Vaccine-based therapy directed against carcinoembryonic antigen demonstrates antitumor activity on spontaneous intestinal tumors in the absence of autoimmunity.

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Selective induction of high avidity CTL by altering the balance of signals from APC.

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Prognostic model for predicting survival in men with hormone-refractory metastatic prostate cancer.

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Modified vaccinia virus ankara recombinants are as potent as vaccinia recombinants in diversified prime and boost vaccine regimens to elicit therapeutic antitumor responses.

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Combination of a poxvirus-based vaccine with a cyclooxygenase-2 inhibitor (celecoxib) elicits antitumor immunity and long-term survival in CEA.Tg/MIN mice

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Snail blocks the cell cycle and confers resistance to cell death

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12 December 2020

Phase II randomized study of vaccine treatment of advanced prostate cancer (E7897): a trial of the Eastern Cooperative Oncology Group

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External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccine-mediated T-cell killing

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12 December 2020

Fusion cell vaccination of patients with metastatic breast and renal cancer induces immunological and clinical responses

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12 December 2020

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Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes

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Phase I study of sequential vaccinations with fowlpox-CEA(6D)-TRICOM alone and sequentially with vaccinia-CEA(6D)-TRICOM, with and without granulocyte-macrophage colony-stimulating factor, in patients with carcinoembryonic antigen-expressing carcino

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12 December 2020

Analysis of preoperative prognostic factors for long-term survival after hepatic resection of liver metastasis of colorectal carcinoma

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12 December 2020

Induction of an antigen cascade by diversified subcutaneous/intratumoral vaccination is associated with antitumor responses

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12 December 2020

Effect of surgical margin status on survival and site of recurrence after hepatic resection for colorectal metastases

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12 December 2020

Combining a recombinant cancer vaccine with standard definitive radiotherapy in patients with localized prostate cancer

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12 December 2020

Multiple costimulatory modalities enhance CTL avidity

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12 December 2020

The requirement of multimodal therapy (vaccine, local tumor radiation, and reduction of suppressor cells) to eliminate established tumors

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12 December 2020

Antiandrogen, vaccine and combination therapy in patients with nonmetastatic hormone refractory prostate cancer

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12 December 2020

Randomized phase IIB trial of BLP25 liposome vaccine in stage IIIB and IV non-small-cell lung cancer

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12 December 2020

Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition

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12 December 2020

Immunogenicity, Including Vitiligo, and Feasibility of Vaccination With AutologousGM-CSF–Transduced Tumor Cells in Metastatic Melanoma Patients

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12 December 2020

A randomized phase II study of concurrent docetaxel plus vaccine versus vaccine alone in metastatic androgen-independent prostate cancer

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12 December 2020

Complex networks orchestrate epithelial-mesenchymal transitions

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12 December 2020

Combination chemotherapy and radiation of human squamous cell carcinoma of the head and neck augments CTL-mediated lysis.

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12 December 2020

4-1BB ligand enhances tumor-specific immunity of poxvirus vaccines

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12 December 2020

Immune suppression in the tumor microenvironment

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12 December 2020

Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines

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12 December 2020

Immune resistance orchestrated by the tumor microenvironment

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12 December 2020

Clinical benefit associated with idiotypic vaccination in patients with follicular lymphoma

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12 December 2020

Listeria monocytogenes as a vector for tumor-associated antigens for cancer immunotherapy.

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12 December 2020

A novel DNA vaccine encoding PDGFRbeta suppresses growth and dissemination of murine colon, lung and breast carcinoma

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12 December 2020

A pilot trial of CTLA-4 blockade with human anti-CTLA-4 in patients with hormone-refractory prostate cancer

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12 December 2020

Avidity of CD8 T cells sharpens immunodominance

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12 December 2020

Frequent and specific immunity to the embryonal stem cell-associated antigen SOX2 in patients with monoclonal gammopathy

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12 December 2020

The human T-box mesodermal transcription factor Brachyury is a candidate target for T-cell-mediated cancer immunotherapy.

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12 December 2020

Intratumoral delivery of vector mediated IL-2 in combination with vaccine results in enhanced T cell avidity and anti-tumor activity

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12 December 2020

Immunization of high-risk breast cancer patients with clustered sTn-KLH conjugate plus the immunologic adjuvant QS-21.

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12 December 2020

Clinical safety of a viral vector based prostate cancer vaccine strategy

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12 December 2020

Improved long-term outcome of surgery for advanced colorectal liver metastases: reasons and implications for management on the basis of a severity score

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12 December 2020

Prevention of cancer through immunization: Prospects and challenges for the 21st century.

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12 December 2020

Analysis of prognostic factors influencing long-term survival after hepatic resection for metastatic colorectal cancer

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12 December 2020

Use of radiolabeled monoclonal antibody to enhance vaccine-mediated antitumor effects

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12 December 2020

Allogeneic granulocyte macrophage colony-stimulating factor-secreting tumor immunotherapy alone or in sequence with cyclophosphamide for metastatic pancreatic cancer: a pilot study of safety, feasibility, and immune activation

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12 December 2020

Oral DNA vaccines target the tumor vasculature and microenvironment and suppress tumor growth and metastasis

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12 December 2020

Three phase II cytokine working group trials of gp100 (210M) peptide plus high-dose interleukin-2 in patients with HLA-A2-positive advanced melanoma

1 reference

12 December 2020

Pilot study of vaccination with recombinant CEA-MUC-1-TRICOM poxviral-based vaccines in patients with metastatic carcinoma

1 reference

12 December 2020

Combination of docetaxel and recombinant vaccine enhances T-cell responses and antitumor activity: effects of docetaxel on immune enhancement

1 reference

12 December 2020

Evaluation of systemic and mucosal anti-HPV16 and anti-HPV18 antibody responses from vaccinated women

1 reference

12 December 2020

Cancer immunotherapy targeting tumour-specific antigens: towards a new therapy for minimal residual disease

1 reference

12 December 2020

The use of chelated radionuclide (samarium-153-ethylenediaminetetramethylenephosphonate) to modulate phenotype of tumor cells and enhance T cell-mediated killing

1 reference

12 December 2020

Vaccination with a recombinant Saccharomyces cerevisiae expressing a tumor antigen breaks immune tolerance and elicits therapeutic antitumor responses.

1 reference

12 December 2020

Analysis of overall survival in patients with nonmetastatic castration-resistant prostate cancer treated with vaccine, nilutamide, and combination therapy

1 reference

12 December 2020

Immune reconstitution and implications for immunotherapy following haematopoietic stem cell transplantation

1 reference

12 December 2020

Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells

1 reference

12 December 2020

Balancing between antitumor efficacy and autoimmune pathology in T-cell-mediated targeting of carcinoembryonic antigen

1 reference

12 December 2020

Sunitinib reverses type-1 immune suppression and decreases T-regulatory cells in renal cell carcinoma patients

1 reference

12 December 2020

Seromic analysis of antibody responses in non-small cell lung cancer patients and healthy donors using conformational protein arrays.

1 reference

12 December 2020

Breast cancer cells expressing stem cell markers CD44+ CD24 lo are eliminated by Numb-1 peptide-activated T cells.

1 reference

12 December 2020

Human dendritic cell maturation and activation by a heat-killed recombinant yeast (Saccharomyces cerevisiae) vector encoding carcinoembryonic antigen

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12 December 2020

Synthesis of sialyl Lewis(a) (sLe (a), CA19-9) and construction of an immunogenic sLe(a) vaccine

1 reference

12 December 2020

Optimization of vaccine responses with an E1, E2b and E3-deleted Ad5 vector circumvents pre-existing anti-vector immunity.

1 reference

12 December 2020

Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits

1 reference

12 December 2020

Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients

1 reference

12 December 2020

MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment

1 reference

12 December 2020

Autoantibodies against cancer antigens

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12 December 2020

MUC1* is a determinant of trastuzumab (Herceptin) resistance in breast cancer cells

1 reference

12 December 2020

High antigen levels are the cause of T cell exhaustion during chronic viral infection

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12 December 2020

Harnessing the unique local immunostimulatory properties of modified vaccinia Ankara (MVA) virus to generate superior tumor-specific immune responses and antitumor activity in a diversified prime and boost vaccine regimen

1 reference

12 December 2020

The basics of epithelial-mesenchymal transition

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12 December 2020

Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer

1 reference

12 December 2020

Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells

1 reference

12 December 2020

Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer

1 reference

12 December 2020

Idiotype vaccines for lymphoma: proof-of-principles and clinical trial failures

1 reference

12 December 2020

The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research

1 reference

12 December 2020

Concurrent vaccination with two distinct vaccine platforms targeting the same antigen generates phenotypically and functionally distinct T-cell populations

1 reference

12 December 2020

Timed sequential treatment with cyclophosphamide, doxorubicin, and an allogeneic granulocyte-macrophage colony-stimulating factor-secreting breast tumor vaccine: a chemotherapy dose-ranging factorial study of safety and immune activation

1 reference

12 December 2020

Therapeutic vaccines in metastatic castration-resistant prostate cancer: principles in clinical trial design.

1 reference

12 December 2020

Enhancing cancer vaccine efficacy via modulation of the tumor microenvironment

1 reference

12 December 2020

Immunogenic death of colon cancer cells treated with oxaliplatin

1 reference

12 December 2020

Immunologic and prognostic factors associated with overall survival employing a poxviral-based PSA vaccine in metastatic castrate-resistant prostate cancer

1 reference

12 December 2020

Mucins in cancer: function, prognosis and therapy

1 reference

12 December 2020

Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging study

1 reference

12 December 2020

Phase I study of recombinant human interleukin-7 administration in subjects with refractory malignancy

1 reference

12 December 2020

The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells

1 reference

12 December 2020

Effect of a small molecule BCL-2 inhibitor on immune function and use with a recombinant vaccine

1 reference

12 December 2020

Overall survival analysis of a phase II randomized controlled trial of a Poxviral-based PSA-targeted immunotherapy in metastatic castration-resistant prostate cancer

1 reference

12 December 2020

Seromic profiling of ovarian and pancreatic cancer

1 reference

12 December 2020

Features of responding T cells in cancer and chronic infection.

1 reference

12 December 2020

Androgen ablation augments human HLA2.1-restricted T cell responses to PSA self-antigen in transgenic mice

1 reference

12 December 2020

Tumor microvasculature and microenvironment: novel insights through intravital imaging in pre-clinical models

1 reference

12 December 2020

Natural immunity to pluripotency antigen OCT4 in humans

1 reference

12 December 2020

Direct and differential suppression of myeloid-derived suppressor cell subsets by sunitinib is compartmentally constrained

1 reference

12 December 2020

Survival after Hepatic Resection for Metastatic Colorectal Cancer: Trends in Outcomes for 1,600 Patients during Two Decades at a Single Institution

1 reference

12 December 2020

Immunogenic tumor cell death for optimal anticancer therapy: the calreticulin exposure pathway

1 reference

12 December 2020

MUC1-associated proliferation signature predicts outcomes in lung adenocarcinoma patients

1 reference

12 December 2020

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

1 reference

12 December 2020

Generation of a tumor vaccine candidate based on conjugation of a MUC1 peptide to polyionic papillomavirus virus-like particles

1 reference

12 December 2020

MUC1 oncogene amplification correlates with protein overexpression in invasive breast carcinoma cells

1 reference

12 December 2020

A novel chemoimmunomodulating property of docetaxel: suppression of myeloid-derived suppressor cells in tumor bearers.

1 reference

12 December 2020

Therapeutic Cancer Vaccines in Prostate Cancer: The Paradox of Improved Survival Without Changes in Time to Progression

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12 December 2020

Sipuleucel-T immunotherapy for castration-resistant prostate cancer

1 reference

12 December 2020

Improved Endpoints for Cancer Immunotherapy Trials

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12 December 2020

The Thymus and the Immune System: Layered Levels of Control

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12 December 2020

A decrease of regulatory T cells correlates with overall survival after sunitinib-based antiangiogenic therapy in metastatic renal cancer patients

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12 December 2020

Desirable cell death during anticancer chemotherapy

1 reference

12 December 2020

MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition

1 reference

12 December 2020

Spontaneous and therapy-induced immunity to pluripotency genes in humans: clinical implications, opportunities and challenges

1 reference

12 December 2020

Tumor Regression and Growth Rates Determined in Five Intramural NCI Prostate Cancer Trials: The Growth Rate Constant as an Indicator of Therapeutic Efficacy

1 reference

12 December 2020

Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcellulo

1 reference

12 December 2020

T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis.

1 reference

12 December 2020

Efficient in vivo priming by vaccination with recombinant NY-ESO-1 protein and CpG in antigen naive prostate cancer patients

1 reference

12 December 2020

A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma. A Phase II trial of safety, efficacy, and immune activation

1 reference

12 December 2020

Immunologic biomarkers as correlates of clinical response to cancer immunotherapy

1 reference

12 December 2020

HPV16/18 L1 VLP vaccine induces cross-neutralizing antibodies that may mediate cross-protection

1 reference

12 December 2020

Molecular determinants of immunogenic cell death elicited by anticancer chemotherapy

1 reference

12 December 2020

Dependence on the MUC1-C oncoprotein in non-small cell lung cancer cells

1 reference

12 December 2020

The CD133+ tumor stem-like cell-associated antigen may elicit highly intense immune responses against human malignant glioma

1 reference

12 December 2020

Tumor-infiltrating immune cells and prognosis: the potential link between conventional cancer therapy and immunity

1 reference

12 December 2020

Recommendations from the iSBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers

1 reference

12 December 2020

Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

1 reference

12 December 2020

gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma

1 reference

12 December 2020

Vaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma

1 reference

12 December 2020

Consequence of dose scheduling of sunitinib on host immune response elements and vaccine combination therapy

1 reference

12 December 2020

Impact of tumour volume on the potential efficacy of therapeutic vaccines

1 reference

12 December 2020

Epitope spreading contributes to effective immunotherapy in metastatic melanoma patients.

1 reference

12 December 2020

Vaccines for glioblastoma and high-grade glioma

1 reference

12 December 2020

Importance of MUC1 and spontaneous mouse tumor models for understanding the immunobiology of human adenocarcinomas

1 reference

12 December 2020

4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection

1 reference

12 December 2020

Systems biology of vaccination for seasonal influenza in humans

1 reference

12 December 2020

Comparison of two CD40-ligand/interleukin-2 vaccines in patients with chronic lymphocytic leukemia

1 reference

12 December 2020

Viral vector-based therapeutic cancer vaccines

1 reference

12 December 2020

A pilot study of MUC-1/CEA/TRICOM poxviral-based vaccine in patients with metastatic breast and ovarian cancer

1 reference

12 December 2020

The immune score as a new possible approach for the classification of cancer

1 reference

12 December 2020

The secret ally: immunostimulation by anticancer drugs

1 reference

12 December 2020

Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial

1 reference

12 December 2020

Ipilimumab and a poxviral vaccine targeting prostate-specific antigen in metastatic castration-resistant prostate cancer: a phase 1 dose-escalation trial

1 reference

12 December 2020

Therapeutic cancer vaccines: current status and moving forward

1 reference

12 December 2020

The immune contexture in human tumours: impact on clinical outcome

1 reference

12 December 2020

Combining immunotherapy and targeted therapies in cancer treatment

1 reference

12 December 2020

Brachyury, a driver of the epithelial-mesenchymal transition, is overexpressed in human lung tumors: an opportunity for novel interventions against lung cancer

1 reference

12 December 2020

Multipeptide immune response to cancer vaccine IMA901 after single-dose cyclophosphamide associates with longer patient survival

1 reference

12 December 2020

MUC1c regulates cell survival in pancreatic cancer by preventing lysosomal permeabilization

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12 December 2020

Therapeutic vaccines: the ultimate personalized therapy?

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12 December 2020

Inhibition of the MUC1-C oncoprotein is synergistic with cytotoxic agents in the treatment of breast cancer cells

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12 December 2020

Oncogenic MUC1-C promotes tamoxifen resistance in human breast cancer

1 reference

12 December 2020

Novel adenoviral vector induces T-cell responses despite anti-adenoviral neutralizing antibodies in colorectal cancer patients

1 reference

12 December 2020

A randomized phase II study of immunization with dendritic cells modified with poxvectors encoding CEA and MUC1 compared with the same poxvectors plus GM-CSF for resected metastatic colorectal cancer.

1 reference

12 December 2020

Dramatic and prolonged PSA response after retreatment with a PSA vaccine.

1 reference

12 December 2020

Identification and characterization of agonist epitopes of the MUC1-C oncoprotein.

1 reference

12 December 2020

Admixture of a recombinant vaccinia virus containing the gene for the costimulatory molecule B7 and a recombinant vaccinia virus containing a tumor-associated antigen gene results in enhanced specific T-cell responses and antitumor immunity

1 reference

12 December 2020

Adjuvant active specific immunotherapy for human colorectal cancer: 6.5-year median follow-up of a phase III prospectively randomized trial

1 reference

12 December 2020

Genetically engineered poxviruses for recombinant gene expression, vaccination, and safety

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12 December 2020

Construction and characterization of a recombinant vaccinia virus expressing murine intercellular adhesion molecule-1: induction and potentiation of antitumor responses

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12 December 2020

Dendritic cells and the control of immunity

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12 December 2020

Mice transgenic for human carcinoembryonic antigen as a model for immunotherapy

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12 December 2020

A role for CTLA-4-mediated inhibitory signals in peripheral T cell tolerance?

1 reference

12 December 2020

Recombinant vaccinia-PSA (PROSTVAC) can induce a prostate-specific immune response in androgen-modulated human prostate cancer

1 reference

12 December 2020

Induction of protective host immunity to carcinoembryonic antigen (CEA), a self-antigen in CEA transgenic mice, by immunizing with a recombinant vaccinia-CEA virus.

1 reference

12 December 2020

10.1016/B978-0-12-800249-0.00002-0

Identifiers

DOI

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1 July 2019

PMC publication ID

6324585

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1 July 2019

PubMed publication ID

24889529

1 reference

1 July 2019