(Q71671364)

English

Solid-state stability of human insulin. I. Mechanism and the effect of water on the kinetics of degradation in lyophiles from pH 2-5 solutions

scientific article published on 01 August 1996

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8865303%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

Solid-state stability of human insulin. I. Mechanism and the effect of water on the kinetics of degradation in lyophiles from pH 2-5 solutions (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8865303%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

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author name string

R G Strickley

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8865303%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

B D Anderson

2

1 reference

Europe PubMed Central

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20 October 2019

publication date

1 August 1996

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8865303%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8865303%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

13

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20 October 2019

8

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8865303%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

1142-1153

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8865303%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

Major degradation products of basic fibroblast growth factor: detection of succinimide and iso-aspartate in place of aspartate

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical pathways of degradation of the bradykinin analog, RMP-7

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship between the glass transition temperature and water vapor absorption by poly(vinylpyrrolidone)

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haemoglobin lyophilized with sucrose: the effect of residual moisture on storage

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequential hydration of dry proteins: a direct difference IR investigation of sequence homologs lysozyme and alpha- lactalbumin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmaceutics of protein drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mobility of amorphous pharmaceutical solids below their glass transition temperatures

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Moisture-induced aggregation of lyophilized proteins in the solid state

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beyond water activity: Recent advances based on an alternative approach to the assessment of food quality and safety

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-performance liquid chromatographic (HPLC) and HPLC-mass spectrometric (MS) analysis of the degradation of the luteinizing hormone-releasing hormone (LH-RH) antagonist RS-26306 in aqueous solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlation of IR spectroscopic, heat capacity, diamagnetic susceptibility and enzymatic measurements on lysozyme powder

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fingerprint analysis of insulin and proinsulins

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a common intermediate in insulin deamidation and covalent dimer formation: effects of pH and aniline trapping in dilute acidic solutions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mobility in mixtures of absorbed water and solid poly(vinylpyrrolidone).

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical pathways of peptide degradation. VII. Solid state chemical instability of an aspartyl residue in a model hexapeptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thermal decomposition of amorphous beta-lactam antibacterials

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of formulation variables on the stability of freeze-dried human growth hormone

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of glasses from liquids and biopolymers

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemical properties of the functional groups of insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of insulin concentration and self-association on the partitioning of its A-21 cyclic anhydride intermediate to desamido insulin and covalent dimer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of intramolecular nucleophilic catalysis and the effects of self-association on the deamidation of human insulin at low pH

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural details of Asp(B9) human insulin at low pH from two-dimensional NMR titration studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physical stabilization of insulin by glycosylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of formulation and moisture on the stability of a freeze-dried monoclonal antibody-vinca conjugate: a test of the WLF glass transition theory

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stability of protein pharmaceuticals

1 reference

https://pubmed.ncbi.nlm.nih.gov/8865303

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1016043715791

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8865303%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8865303%20AND%20SRC:MED&resulttype=core&format=json

20 October 2019

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