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English
Methylation of the p16(Ink4a) tumor suppressor gene 5'-CpG island in breast cancer
scientific article published on 01 February 2001
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11163109
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11163109%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
title
Methylation of the p16(Ink4a) tumor suppressor gene 5'-CpG island in breast cancer
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11163109
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11163109%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
main subject
CpG island
1 reference
based on heuristic
inferred from title
breast cancer
1 reference
based on heuristic
inferred from title
author
Göran Roos
series ordinal
2
object named as
G Roos
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11163109
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11163109%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
author name string
N H Nielsen
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11163109
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11163109%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
S O Emdin
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11163109
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11163109%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
G Landberg
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11163109
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11163109%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
language of work or name
English
0 references
publication date
1 February 2001
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11163109
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11163109%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
published in
Cancer Letters
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11163109
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11163109%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
volume
163
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11163109
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11163109%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
issue
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11163109
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11163109%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
page(s)
59-69
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11163109
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11163109%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
cites work
Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sp1 elements protect a CpG island from de novo methylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Infrequent CDKN2 (MTS1/p16) gene alterations in human primary breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of p16 gene deletion and point mutation in breast carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of MTS1/CDK4 in female breast carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequency of homozygous deletion at p16/CDKN2 in primary human tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of p16 gene (CDKN2) deletions in microdissected primary breast carcinoma specimens.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retinoblastoma and p16 proteins in mammary carcinoma: their relationship to cyclin D1 and histopathological parameters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Frequent alterations of cell cycle regulators in early-stage breast lesions as detected by immunohistochemistry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypomethylation and increased gene expression of p16INK4a in primary and metastatic breast carcinoma as compared to normal breast tissue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin E overexpression, a negative prognostic factor in breast cancer with strong correlation to oestrogen receptor status
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA methylation in the promoter region of the p16 (CDKN2/MTS-1/INK4A) gene in human breast tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CpNpG methylation in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G1-S transition defects occur in most breast cancers and predict outcome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alterations of p16-pRb pathway and chromosome locus 9p21-22 in sporadic invasive breast carcinomas.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of p16 in human mammary epithelial cells by CpG island methylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytosines adjacent to methylated CpG sites can be partially resistant to conversion in genomic bisulfite sequencing leading to methylation artifacts.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sp1 binding is inhibited by (m)Cp(m)CpG methylation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0304-3835%2800%2900674-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0304-3835(00)00674-1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11163109
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11163109%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
PubMed publication ID
11163109
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11163109
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11163109%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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