(Q73434313)

English

Transactivation of the p21 promoter by BRCA1 splice variants in mammary epithelial cells: evidence for both common and distinct activities of wildtype and mutant forms

scientific article published on 01 December 2000

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175350%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Transactivation of the p21 promoter by BRCA1 splice variants in mammary epithelial cells: evidence for both common and distinct activities of wildtype and mutant forms (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175350%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

Lu M

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175350%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Arrick BA

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175350%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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publication date

1 December 2000

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175350%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11175350%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

19

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Europe PubMed Central

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3 November 2019

54

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Europe PubMed Central

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3 November 2019

6351-6360

1 reference

Europe PubMed Central

PubMed publication ID

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3 November 2019

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204025

0 references

The cancer-predisposing mutation C61G disrupts homodimer formation in the NH2-terminal BRCA1 RING finger domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcriptional activation by BRCA1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Emerging roles of BRCA1 in transcriptional regulation and DNA repair

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1 mutations in primary breast and ovarian carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Incidence of BRCA1/2 germ line alterations in a high risk cohort participating in a phase II chemoprevention trial

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Down-regulation of BRCA1 in human sporadic breast cancer; analysis of DNA methylation patterns of the putative promoter region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence for a transcriptional activation function of BRCA1 C-terminal region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1 regulates p53-dependent gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

CBP/p300 interact with and function as transcriptional coactivators of BRCA1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Quantification of BRCA1 protein in sporadic breast carcinoma with or without loss of heterozygosity of the BRCA1 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Genetic analysis of BRCA1 function in a defined tumor cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1 expression levels predict distant metastasis of sporadic breast cancers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Localization of BRCA1 and a splice variant identifies the nuclear localization signal

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Insights into the functions of BRCA1 and BRCA2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-delta11b

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1 physically associates with p53 and stimulates its transcriptional activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1204025

7 January 2021

based on heuristic

inferred from DOI database lookup

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