(Q73446293)

English

Resistance to DNA-damaging agents is discordant from experimental metastatic capacity in MEF ras-transformants-expressing gain of function MTp53

scientific article published on 01 May 2003

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scholarly article

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4 November 2019

Resistance to DNA-damaging agents is discordant from experimental metastatic capacity in MEF ras-transformants-expressing gain of function MTp53 (English)

1 reference

Europe PubMed Central

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4 November 2019

Robert G. Bristow

1

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4 November 2019

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James Peacock

2

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4 November 2019

Anne Jang

3

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4 November 2019

John Kim

4

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4 November 2019

Richard P Hill

5

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4 November 2019

Samuel Benchimol

6

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4 November 2019

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1 May 2003

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4 November 2019

1 reference

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4 November 2019

22

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4 November 2019

2960-2966

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4 November 2019

19

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4 November 2019

https://scigraph.springernature.com/pub.10.1038/sj.onc.1206405

0 references

DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis

1 reference

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7 January 2021

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Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy

1 reference

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7 January 2021

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The p53 gene as a modifier of intrinsic radiosensitivity: implications for radiotherapy

1 reference

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7 January 2021

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Radioresistant MTp53-expressing rat embryo cell transformants exhibit increased DNA-dsb rejoining during exposure to ionizing radiation

1 reference

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7 January 2021

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Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

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The effects of wild-type p53 tumor suppressor activity and mutant p53 gain-of-function on cell growth

1 reference

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7 January 2021

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Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs

1 reference

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7 January 2021

based on heuristic

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Gain of function mutations in p53.

1 reference

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7 January 2021

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

based on heuristic

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Pharmacological rescue of mutant p53 conformation and function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

based on heuristic

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A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of different mutant p53 transgenes in neuroblastoma cells leads to different cellular responses to genotoxic agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

based on heuristic

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Mutant p53 correlates with reduced expression of thrombospondin-1, increased angiogenesis, and metastatic progression in melanoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

based on heuristic

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An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

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Genome maintenance mechanisms for preventing cancer

1 reference

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7 January 2021

based on heuristic

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Polyploid giant cells provide a survival mechanism for p53 mutant cells after DNA damage.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

based on heuristic

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Tumor-suppressor p53: implications for tumor development and prognosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

based on heuristic

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Mutant p53 protein expression interferes with p53-independent apoptotic pathways.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

based on heuristic

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Cytokines inhibit p53-mediated apoptosis but not p53-mediated G1 arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

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P53 gene mutations: case study of a clinical marker for solid tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

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High metastatic potential in mice inheriting a targeted p53 missense mutation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

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Tumour p53 mutations exhibit promoter selective dominance over wild type p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

based on heuristic

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A role for p53 in the frequency and mechanism of mutation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

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Structural and functional involvement of p53 in BER in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

based on heuristic

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The p53-mediated G1 checkpoint is retained in tumorigenic rat embryo fibroblast clones transformed by the human papillomavirus type 16 E7 gene and EJ-ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

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Novel gain of function activity of p53 mutants: activation of the dUTPase gene expression leading to resistance to 5-fluorouracil

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

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P53 gene replacement for cancer--interactions with DNA damaging agents

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

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p53: good cop/bad cop.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

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The transforming and suppressor functions of p53 alleles: effects of mutations that disrupt phosphorylation, oligomerization and nuclear translocation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

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p53 regulation of DNA excision repair pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206405

7 January 2021

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Assessing TP53 status in human tumours to evaluate clinical outcome

1 reference

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The mutant p53-conformation modifying drug, CP-31398, can induce apoptosis of human cancer cells and can stabilize wild-type p53 protein

1 reference

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Evidence against apoptosis as a major mechanism for reproductive cell death following treatment of cell lines with anti-cancer drugs

1 reference

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7 January 2021

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The evolution of diverse biological responses to DNA damage: insights from yeast and p53.

1 reference

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Genetic Stabilization by p53 Involves Growth Regulatory and Repair Pathways

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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