(Q73655322)

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Pancreatic NOD beta cells express MHC class II protein and the frequency of I-A(g7) mRNA-expressing beta cells strongly increases during progression to autoimmune diabetes

scientific article published on 10 July 2003

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5 November 2019

Pancreatic NOD beta cells express MHC class II protein and the frequency of I-A(g7) mRNA-expressing beta cells strongly increases during progression to autoimmune diabetes (English)

1 reference

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5 November 2019

Stefan R. Bornstein

10

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S R Bornstein

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5 November 2019

author name string

U Walter

1

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5 November 2019

T Toepfer

2

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5 November 2019

K E J Dittmar

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5 November 2019

K Kretschmer

4

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5 November 2019

J Lauber

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5 November 2019

S Weiss

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5 November 2019

G Servos

7

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5 November 2019

O Lechner

8

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5 November 2019

W A Scherbaum

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5 November 2019

H Von Boehmer

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5 November 2019

J Buer

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5 November 2019

publication date

10 July 2003

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5 November 2019

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5 November 2019

46

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5 November 2019

8

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5 November 2019

1106-1114

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5 November 2019

https://scigraph.springernature.com/pub.10.1007/s00125-003-1164-y

0 references

Characterization of pancreatic islet cell infiltrates in NOD mice: effect of cell transfer and transgene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cytokine-induced MHC class II but not class I molecule expression on mouse islet cells by niacinamide and 3-aminobenzamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-Cell death during progression to diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of class II MHC antigens in vitro on pancreatic B cells isolated from BB/E rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+8- help prevents rapid deletion of CD8+ cells after a transient response to antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental regulation of invariant chain proteolysis controls MHC class II trafficking in mouse dendritic cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoimmune insulitis and diabetes in the absence of antigen-specific contact between T cells and islet beta-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral administration of the immunodominant B-chain of insulin reduces diabetes in a co-transfer model of diabetes in the NOD mouse and is associated with a switch from Th1 to Th2 cytokines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo induction of antigen-specific transplantation tolerance to Qa1a by exposure to alloantigen in the absence of T-cell help

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A self MHC class II beta-chain peptide prevents diabetes in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antigen-presenting cells in adoptively transferred and spontaneous autoimmune diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monitoring gene expression of TNFR family members by beta-cells during development of autoimmune diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN gamma/TNF alpha synergism in MHC class II induction: effect of nicotinamide on MHC class II expression but not on islet-cell apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antigen concentration and precursor frequency determine the rate of CD8+ T cell tolerance to peripherally expressed antigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4+ T cell help impairs CD8+ T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aberrant expression of HLA-DR antigens by insulin-containing beta-cells in recent-onset type I diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transfer of diabetes in the NOD-scid mouse by CD4 T-cell clones. Differential requirement for CD8 T-cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre-diabetes in the spontaneously diabetic BB/E rat: lymphocyte subpopulations in the pancreatic infiltrate and expression of rat MHC class II molecules in endocrine cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-gamma induces islet cell MHC antigens and enhances autoimmune, streptozotocin-induced diabetes in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet abnormalities associated with an early influx of dendritic cells and macrophages in NOD and NODscid mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exclusive Expression of MHC Class II Proteins on CD45+ Cells in Pancreatic Islets of NOD Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Checkpoints in the progression of autoimmune disease: lessons from diabetes models

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demonstration of a TH1 cytokine profile in the late phase of NOD insulitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice lacking the MHC class II-associated invariant chain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transfer of Autoimmune Diabetes from Diabetic NOD Mice to NOD Athymic Nude Mice: The Roles of T Cell Subsets in the Pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinant spreading of T helper cell 2 (Th2) responses to pancreatic islet autoantigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NIT-1, a Pancreatic β-Cell Line Established From a Transgenic NOD/Lt Mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Major histocompatibility complex class I-restricted cross-presentation is biased towards high dose antigens and those released during cellular destruction

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HLA class II induction in human islet cells by interferon-γ plus tumour necrosis factor or lymphotoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD8+ T-cells are required for adoptive transfer of the BB rat diabetic syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reciprocal allogeneic bone marrow transplantation between NOD mice and diabetes-nonsusceptible mice associated with transfer and prevention of autoimmune diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcriptional promoter regulates hypermutation of the antibody heavy chain locus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of MHC protein expression in pancreatic beta-cells by interferon-gamma and tumor necrosis factor-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta cell apoptosis in T cell-mediated autoimmune diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental regulation of MHC class II transport in mouse dendritic cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of diabetes in nonobese diabetic mice by anti-I-A monoclonal antibodies: transfer of protection by splenic T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral tolerance of CD4 T cells following local activation in adolescent mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A fail-safe mechanism for maintaining self-tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GAD-reactive CD4+ Th1 cells induce diabetes in NOD/SCID mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12856083

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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