(Q73675913)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10764786%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

The p53 tumor suppressor stimulates the catalytic activity of human topoisomerase IIalpha by enhancing the rate of ATP hydrolysis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10764786%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

author name string

Kwon Y

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10764786%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Shin BS

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10764786%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Chung IK

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10764786%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

language of work or name

English

0 references

publication date

1 June 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10764786%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

5 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10764786%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

volume

275

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10764786%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

page(s)

18503-18510

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10764786%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

issue

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10764786%20AND%20SRC:MED&resulttype=core&format=json

DNA topoisomerases: essential enzymes and lethal targets

5 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Biochemical basis for the interactions of type I and type II topoisomerases with DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Structure and function of type II DNA topoisomerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Structure and mechanism of DNA topoisomerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

DNA transport by a type II DNA topoisomerase: evidence in favor of a two-gate mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

DNA topoisomerase II mutant of Saccharomyces cerevisiae: topoisomerase II is required for segregation of daughter molecules at the termination of DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

DNA topoisomerase II is required at the time of mitosis in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Illegitimate recombination mediated by calf thymus DNA topoisomerase II in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Supercoiling of the DNA template during transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Topoisomerase II is a structural component of mitotic chromosome scaffolds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

When good enzymes go bad: conversion of topoisomerase II to a cellular toxin by antineoplastic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Topoisomerase poisons: harnessing the dark side of enzyme mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Novel actions of inhibitors of DNA topoisomerase II in drug-resistant tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Quinobenoxazines: a class of novel antitumor quinolones and potent mammalian DNA topoisomerase II catalytic inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Characterization and immunological identification of cDNA clones encoding two human DNA topoisomerase II isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Isolation of cDNA clones encoding the beta isozyme of human DNA topoisomerase II and localisation of the gene to chromosome 3p24

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

p53 regulates the minimal promoter of the human topoisomerase IIalpha gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Inhibition of DNA topoisomerase II alpha gene expression by the p53 tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

21 January 2018

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Suppression of human colorectal carcinoma cell growth by wild-type p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

p53 function and dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Wild-type p53 activates transcription in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Wild-type p53 can down-modulate the activity of various promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Negative regulation of Rb expression by the p53 gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Cloning and characterization of the 5'-flanking region for the human topoisomerase III gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Reduced activity of topoisomerase II in an Adriamycin-resistant human stomach-adenocarcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Induction of topoisomerase II-mediated DNA cleavage by a protoberberine alkaloid, berberrubine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Stabilization of the topoisomerase II-DNA cleavage complex by antineoplastic drugs: inhibition of enzyme-mediated DNA religation by 4'-(9-acridinylamino)methanesulfon-m-anisidide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Mechanism of topoisomerase II inhibition by staurosporine and other protein kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Binding of wild-type p53 by topoisomerase II and overexpression of topoisomerase II in human hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Protein kinase C modulates the catalytic activity of topoisomerase II by enhancing the rate of ATP hydrolysis: evidence for a common mechanism of regulation by phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Modulation of DNA Topoisomerase I Activity byp53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Casein kinase II stabilizes the activity of human topoisomerase IIalpha in a phosphorylation-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Functional interaction between human topoisomerase IIalpha and retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

Human topoisomerase IIalpha and IIbeta interact with the C-terminal region of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

The cell cycle-coupled expression of topoisomerase IIalpha during S phase is regulated by mRNA stability and is disrupted by heat shock or ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M002081200

21 January 2018

Identifiers

DOI

10.1074/JBC.M002081200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10764786%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference