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Negative selection at the pre-BCR checkpoint elicited by human mu heavy chains with unusual CDR3 regions
scientific article published on 01 May 2001
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Europe PubMed Central
PubMed publication ID
11371364
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11371364%20AND%20SRC:MED&resulttype=core&format=json
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7 November 2019
title
Negative selection at the pre-BCR checkpoint elicited by human mu heavy chains with unusual CDR3 regions
(English)
1 reference
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Europe PubMed Central
PubMed publication ID
11371364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11371364%20AND%20SRC:MED&resulttype=core&format=json
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7 November 2019
author name string
Y Minegishi
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1
1 reference
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Europe PubMed Central
PubMed publication ID
11371364
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11371364%20AND%20SRC:MED&resulttype=core&format=json
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7 November 2019
M E Conley
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2
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Europe PubMed Central
PubMed publication ID
11371364
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publication date
1 May 2001
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Europe PubMed Central
PubMed publication ID
11371364
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7 November 2019
published in
Immunity
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Europe PubMed Central
PubMed publication ID
11371364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11371364%20AND%20SRC:MED&resulttype=core&format=json
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7 November 2019
volume
14
1 reference
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Europe PubMed Central
PubMed publication ID
11371364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11371364%20AND%20SRC:MED&resulttype=core&format=json
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7 November 2019
issue
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11371364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11371364%20AND%20SRC:MED&resulttype=core&format=json
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7 November 2019
page(s)
631-641
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11371364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11371364%20AND%20SRC:MED&resulttype=core&format=json
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7 November 2019
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Three-dimensional structure of antibodies
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A DNA insertion/deletion necessitates an aberrant RNA splice accounting for a mu heavy chain disease protein
1 reference
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7 January 2021
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Restricted use of fetal VH3 immunoglobulin genes by unselected B cells in the adult. Predominance of 56p1-like VH genes in common variable immunodeficiency
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Analysis of the human VH gene repertoire. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5(-)/IgM+ B cells
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Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing
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Mutations in btk in patients with presumed X-linked agammaglobulinemia
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Sequence of the human immunoglobulin diversity (D) segment locus: a systematic analysis provides no evidence for the use of DIR segments, inverted D segments, "minor" D segments or D-D recombination
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Functional reconstitution of an immunoglobulin antigen receptor in T cells
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7 January 2021
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Antibody-antigen complexes
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7 January 2021
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Analysis of human VH gene repertoire expression in peripheral CD19+ B cells.
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The RAG proteins and V(D)J recombination: complexes, ends, and transposition
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7 January 2021
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Recent advances in understanding V(D)J recombination.
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7 January 2021
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Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.
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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
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B cell development regulated by gene rearrangement: arrest of maturation by membrane-bound D mu protein and selection of DH element reading frames
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7 January 2021
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Immunoglobulin heavy chain binding protein
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7 January 2021
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Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
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7 January 2021
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Immunoglobulin heavy chain and binding protein complexes are dissociated in vivo by light chain addition
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7 January 2021
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Assembly and secretion of heavy chains that do not associate posttranslationally with immunoglobulin heavy chain-binding protein
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7 January 2021
based on heuristic
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Assembly of the truncated immunoglobulin heavy chain D mu into antigen receptor-like complexes in pre-B cells but not in B cells
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Only DFL16, DSP2, and DQ52 gene families exist in mouse immunoglobulin heavy chain diversity gene loci, of which DFL16 and DSP2 originate from the same primordial DH gene
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The proteins encoded by the VpreB and lambda 5 pre-B cell-specific genes can associate with each other and with mu heavy chain
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Surrogate light chain in B cell development.
1 reference
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Crossref
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7 January 2021
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A critical role of λ5 protein in B cell development
1 reference
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Crossref
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7 January 2021
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Somatic hypermutation in normal and transformed human B cells
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7 January 2021
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Recombination between an expressed immunoglobulin heavy-chain gene and a germline variable gene segment in a Ly 1+ B-cell lymphoma
1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Fate of surrogate light chains in B lineage cells
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Adult B-cell repertoire is biased toward two heavy-chain variable-region genes that rearrange frequently in fetal pre-B cells
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
BiP and immunoglobulin light chain cooperate to control the folding of heavy chain and ensure the fidelity of immunoglobulin assembly
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
The surrogate light chain in B-cell development.
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7 January 2021
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The VDJ repertoire expressed in human preB cells reflects the selection of bona fide heavy chains
1 reference
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Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the human lambda5/14.1 gene result in B cell deficiency and agammaglobulinemia
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in Igalpha (CD79a) result in a complete block in B-cell development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
An essential role for BLNK in human B cell development
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor selection in B and T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Surrogate or conventional light chains are required for membrane immunoglobulin mu to activate the precursor B cell transition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Prematurely Expressed Igκ Transgene, but Not a VκJκ Gene Segment Targeted into the Igκ Locus, Can Rescue B Cell Development in λ5-Deficient Mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
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7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular basis of the cell-surface expression of immunoglobulin mu chain without light chain in human B lymphocytes
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Restricted utilization of germ-line VH3 genes and short diverse third complementarity-determining regions (CDR3) in human fetal B lymphocyte immunoglobulin heavy chain rearrangements
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clonal selection and learning in the antibody system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antigen receptors on B lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Novel immunoglobulin heavy chains are produced from DJH gene segment rearrangements in lymphoid cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel VH to VHDJH joining mechanism in heavy-chain-negative (null) pre-B cells results in heavy-chain production.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preferential utilization of conserved immunoglobulin heavy chain variable gene segments during human fetal life
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early restriction of the human antibody repertoire.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Developmental regulation of IgM secretion: the role of the carboxy-terminal cysteine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Precursor B cells showing H chain allelic inclusion display allelic exclusion at the level of pre-B cell receptor surface expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Somatic generation of antibody diversity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of B lymphocyte development by the truncated immunoglobulin heavy chain protein Dmu.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The products of pre-B cell-specific genes (lambda 5 and VpreB) and the immunoglobulin mu chain form a complex that is transported onto the cell surface
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor revision of immunoglobulin heavy chain variable region genes in normal human B lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Diversity in the CDR3 region of V(H) is sufficient for most antibody specificities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in the mu heavy-chain gene in patients with agammaglobulinemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900131-5
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1074-7613(01)00131-5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11371364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11371364%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
PubMed publication ID
11371364
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11371364
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11371364%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 November 2019
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