(Q73924716)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10867173%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

title

Familial Alzheimer's disease-associated mutations block translocation of full-length presenilin 1 to the nuclear envelope (English)

1 reference

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7 November 2019

author name string

T Honda

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10867173%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

N Nihonmatsu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10867173%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

K Yasutake

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10867173%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

A Ohtake

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10867173%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

K Sato

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10867173%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

S Tanaka

6

1 reference

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7 November 2019

O Murayama

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10867173%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

M Murayama

8

1 reference

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7 November 2019

A Takashima

9

1 reference

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7 November 2019

publication date

1 June 2000

1 reference

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7 November 2019

published in

Neuroscience Research

1 reference

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7 November 2019

volume

37

1 reference

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7 November 2019

issue

2

1 reference

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7 November 2019

page(s)

101-111

1 reference

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The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families

7 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Isolation of pure and unaltered liver nuclei morphology and biochemical composition

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Novel beta-secretase cleavage of beta-amyloid precursor protein in the endoplasmic reticulum/intermediate compartment of NT2N cells

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Alzheimer's disease associated presenilin-1 holoprotein and its 18-20 kDa C-terminal fragment are death substrates for proteases of the caspase family

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Developmental regulation of presenilin-1 processing in the brain suggests a role in neuronal differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Dual roles of proteasome in the metabolism of presenilin 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Aggresomes: a cellular response to misfolded proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Alzheimer presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Presenilins are processed by caspase-type proteases.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Characterization of human presenilin 1 using N-terminal specific monoclonal antibodies: Evidence that Alzheimer mutations affect proteolytic processing.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Direct association of presenilin-1 with beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Presenilin Proteins Undergo Heterogeneous Endoproteolysis between Thr291and Ala299and Occur as Stable N- and C-Terminal Fragments in Normal and Alzheimer Brain Tissue

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Amino- and carboxyl-terminal heterogeneity of beta-amyloid peptides deposited in human brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Localization of Alzheimer-associated presenilin 1 in transfected COS-7 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Abrogation of the presenilin 1/beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Evidence that levels of presenilins (PS1 and PS2) are coordinately regulated by competition for limiting cellular factors.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Enhanced production and oligomerization of the 42-residue amyloid beta-protein by Chinese hamster ovary cells stably expressing mutant presenilins

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

Presenilin 1 interaction in the brain with a novel member of the Armadillo family

1 reference

https://api.crossref.org/works/10.1016%2FS0168-0102%2800%2900106-1

7 January 2021

10.1016/S0168-0102(00)00106-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10867173%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference