(Q74131196)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10931658%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

ADME/PK as part of a rational approach to drug discovery (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10931658%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

Eddershaw PJ

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10931658%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Beresford AP

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10931658%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Bayliss MK

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10931658%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

publication date

1 September 2000

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10931658%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10931658%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10931658%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

issue

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10931658%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

page(s)

409-414

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10931658%20AND%20SRC:MED&resulttype=core&format=json

Pharmaceutical innovation by the seven UK-owned pharmaceutical companies (1964-1985)

9 November 2019

cites work

1 reference

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7 January 2021

Microtiter plate assays for inhibition of human, drug-metabolizing cytochromes P450

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7 January 2021

Fully automated analysis of activities catalysed by the major human liver cytochrome P450 (CYP) enzymes: assessment of human CYP inhibition potential

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7 January 2021

Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions

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7 January 2021

Characterization of pharmacodynamic recession slopes for direct and indirect response models

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7 January 2021

Characteristics of indirect pharmacodynamic models and applications to clinical drug responses

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7 January 2021

Preclinical drug metabolism in the age of high-throughput screening: an industrial perspective

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7 January 2021

Design of drugs involving the concepts and theories of drug metabolism and pharmacokinetics

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7 January 2021

Approaches to higher-throughput pharmacokinetics (HTPK) in drug discovery

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7 January 2021

Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond

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7 January 2021

In vitro permeability through caco-2 cells is not quantitatively predictive of in vivo absorption for peptide-like drugs absorbed via the dipeptide transporter system

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7 January 2021

Advances in drug metabolism screening

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7 January 2021

In vitro methods for assessing human hepatic drug metabolism: their use in drug development

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7 January 2021

MDCK (Madin-Darby canine kidney) cells: A tool for membrane permeability screening

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7 January 2021

Properties of an immortalised vascular endothelial/glioma cell co-culture model of the blood-brain barrier

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7 January 2021

Virtual screening—an overview

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7 January 2021

Quantitative structure-activity relationships of cytochrome P-450.

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7 January 2021

Design of drugs through a consideration of drug metabolism and pharmacokinetics

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7 January 2021

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901540-3

7 January 2021

Computational methods for the prediction of 'drug-likeness'

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901540-3

7 January 2021

10.1016/S1359-6446(00)01540-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10931658%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference