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Role of BCR affinity in T cell dependent antibody responses in vivo
scientific article published on 20 May 2002
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Europe PubMed Central
PubMed publication ID
12021782
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12021782%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
title
Role of BCR affinity in T cell dependent antibody responses in vivo
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12021782
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12021782%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
author name string
Tien-An Yang Shih
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12021782
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12021782%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
Eric Meffre
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12021782
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12021782%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
Mario Roederer
series ordinal
3
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Europe PubMed Central
PubMed publication ID
12021782
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12021782%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
Michel C Nussenzweig
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12021782
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12021782%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
publication date
20 May 2002
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12021782
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12021782%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
published in
Nature Immunology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12021782
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12021782%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
volume
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12021782
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12021782%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
issue
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12021782
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12021782%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
page(s)
570-575
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12021782
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12021782%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
cites work
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. II. A common clonal origin for periarteriolar lymphoid sheath-associated foci and germinal centers
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Crossref
reference URL
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7 January 2021
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Maturation and dispersal of B-cell clones during T cell-dependent antibody responses
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Crossref
reference URL
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7 January 2021
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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations
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7 January 2021
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Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
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7 January 2021
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Molecular events during maturation of the immune response to oxazolone
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7 January 2021
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Stable expression and somatic hypermutation of antibody V regions in B-cell developmental pathways
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7 January 2021
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Somatic mutation and the maturation of immune response to 2-phenyl oxazolone
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7 January 2021
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Mutation drift and repertoire shift in the maturation of the immune response
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7 January 2021
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Generation of antibody diversity in the immune response of BALB/c mice to influenza virus hemagglutinin
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
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7 January 2021
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inferred from DOI database lookup
Stepwise intraclonal maturation of antibody affinity through somatic hypermutation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
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7 January 2021
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inferred from DOI database lookup
Timing, genetic requirements and functional consequences of somatic hypermutation during B-cell development.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
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7 January 2021
based on heuristic
inferred from DOI database lookup
The repertoire of somatic antibody mutants accumulating in the memory compartment after primary immunization is restricted through affinity maturation and mirrors that expressed in the secondary response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
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7 January 2021
based on heuristic
inferred from DOI database lookup
Maturation of the immune response in germinal centers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
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7 January 2021
based on heuristic
inferred from DOI database lookup
Antibody engineering for the analysis of affinity maturation of an anti-hapten response.
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7 January 2021
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Passenger transgenes reveal intrinsic specificity of the antibody hypermutation mechanism: clustering, polarity, and specific hot spots
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Crossref
reference URL
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7 January 2021
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VARIATIONS IN AFFINITIES OF ANTIBODIES DURING THE IMMUNE RESPONSE
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
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7 January 2021
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Cell Selection by Antigen in the Immune Response
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Crossref
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7 January 2021
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inferred from DOI database lookup
The role of somatic hypermutation in the generation of antibody diversity
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
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7 January 2021
based on heuristic
inferred from DOI database lookup
Accumulation of somatic mutants in the B cell compartment after primary immunization with a T cell-dependent antigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of antigen receptor affinity in T cell-independent antibody responses in vivo
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
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7 January 2021
based on heuristic
inferred from DOI database lookup
Immunization and infection change the number of recombination activating gene (RAG)-expressing B cells in the periphery by altering immature lymphocyte production
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FNI803
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7 January 2021
based on heuristic
inferred from DOI database lookup
FAS is highly expressed in the germinal center but is not required for regulation of the B-cell response to antigen
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
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7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of Fas in B cells of the mouse germinal center and Fas-dependent killing of activated B cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
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7 January 2021
based on heuristic
inferred from DOI database lookup
Intraclonal generation of antibody mutants in germinal centres
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low-level hypermutation in T cell-independent germinal centers compared with high mutation rates associated with T cell-dependent germinal centers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germinal centers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. III. The kinetics of V region mutation and selection in germinal center B cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional and molecular characterization of single, (4-hydroxy-3-nitrophenyl)acetyl (NP)-specific, IgG1+ B cells from antibody-secreting and memory B cell pathways in the C57BL/6 immune response to NP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
B cell memory and the long-lived plasma cell
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Development of antibody diversity in single germinal centers: selective expansion of high-affinity variants.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Memory B cells in T cell-dependent antibody responses colonize the splenic marginal zones.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Memory in the B-cell compartment: antibody affinity maturation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clonal selection and learning in the antibody system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germinal centers develop oligoclonally
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The influence of antigen organization on B cell responsiveness
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Affinity dependence of the B cell response to antigen: a threshold, a ceiling, and the importance of off-rate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular determinants of immunogenicity: the immunon model of immune response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dependence of germinal center B cells on expression of CD21/CD35 for survival.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetic and affinity limits on antibodies produced during immune responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetic maturation of an immune response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antigens varying in affinity for the B cell receptor induce differential B lymphocyte responses.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early high-affinity neutralizing anti-viral IgG responses without further overall improvements of affinity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
B cells extract and present immobilized antigen: implications for affinity discrimination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI803
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NI803
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12021782
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12021782%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
PubMed publication ID
12021782
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12021782
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12021782%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 November 2019
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