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Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis
scientific article published on 01 February 1999
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scholarly article
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stated in
Europe PubMed Central
PubMed ID
10022118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10022118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
title
Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10022118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10022118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
main subject
apoptotic process
1 reference
based on heuristic
inferred from title
author name string
Zhang Y
series ordinal
1
1 reference
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Europe PubMed Central
PubMed ID
10022118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10022118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
Fujita N
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10022118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10022118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
Tsuruo T
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
10022118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10022118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
language of work or name
English
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publication date
1 February 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10022118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10022118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PubMed ID
10022118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10022118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
volume
18
1 reference
stated in
Europe PubMed Central
PubMed ID
10022118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10022118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
page(s)
1131-1138
1 reference
stated in
Europe PubMed Central
PubMed ID
10022118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10022118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
issue
5
1 reference
stated in
Europe PubMed Central
PubMed ID
10022118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10022118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.onc.1202426
0 references
cites work
Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-cycle arrest and inhibition of Cdk4 activity by small peptides based on the carboxy-terminal domain of p21WAF1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Radiation-induced cell cycle arrest compromised by p21 deficiency
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
WAF1, a potential mediator of p53 tumor suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation-induced T-cell death is cell cycle dependent and regulated by cyclin B.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
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7 January 2021
based on heuristic
inferred from DOI database lookup
Acceleration of apoptotic cell death after the cleavage of Bcl-XL protein by caspase-3-like proteases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of cyclin-dependent kinases by p21
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle and apoptosis: common pathways to life and death.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protease activation during apoptosis: death by a thousand cuts?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aspartate-based inhibitor of interleukin-1 beta-converting enzyme prevents antitumor agent-induced apoptosis in human myeloid leukemia U937 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Actin cleavage by CPP-32/apopain during the development of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis and the cell cycle.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of apoptosis by dominant negative mutants of cyclin-dependent protein kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Principles of CDK regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The C-terminal region of p21SDI1/WAF1/CIP1 is involved in proliferating cell nuclear antigen binding but does not appear to be required for growth inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspases: killer proteases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cyclin-dependent kinase inhibitor p21 (WAF1) is required for survival of differentiating neuroblastoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic determinants of p53-induced apoptosis and growth arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A model for p53-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Premature p34cdc2 activation required for apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Substrate specificities of caspase family proteases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspases and caspase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resistance to apoptosis conferred by Cdk inhibitors during myocyte differentiation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21 is a universal inhibitor of cyclin kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202426
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1202426
1 reference
stated in
Europe PubMed Central
PubMed ID
10022118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10022118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
Dimensions Publication ID
1048224360
0 references
PubMed ID
10022118
1 reference
stated in
Europe PubMed Central
PubMed ID
10022118
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10022118%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 November 2019
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