(Q74463323)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9551843%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

title

Valnoctamide, valpromide and valnoctic acid are much less teratogenic in mice than valproic acid (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9551843%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference

ChEBI release 2020-05-28

M Radatz

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9551843%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

K Ehlers

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9551843%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

B Yagen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9551843%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

M Bialer

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9551843%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

H Nau

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9551843%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

publication date

1 March 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9551843%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9551843%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9551843%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

page(s)

41-48

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9551843%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9551843%20AND%20SRC:MED&resulttype=core&format=json

Quantitative structure-anticonvulsant activity relationships of valproic acid, related carboxylic acids and tetrazoles

11 November 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Stereoselective pharmacokinetic analysis of valnoctamide in healthy subjects and in patients with epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Clinical pharmacology of valpromide

1 reference

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7 January 2021

Pharmacokinetics of a valpromide isomer, valnoctamide, in healthy subjects.

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Valproic acid and spina bifida

1 reference

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7 January 2021

Further branching of valproate-related carboxylic acids reduces the teratogenic activity, but not the anticonvulsant effect

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Valproic acid-induced spina bifida: a mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Anticonvulsant and neurotoxic activities of twelve analogues of valproic acid

1 reference

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7 January 2021

Quantitative determination of valproic acid and 14 metabolites in serum and urine by gas chromatography/mass spectrometry

1 reference

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7 January 2021

Pharmacokinetics of a valpromide isomer, valnoctamide, in dogs

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Structure-pharmacokinetic relationships in a series of valpromide derivatives with antiepileptic activity

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7 January 2021

Structure-pharmacokinetic relationships in a series of short fatty acid amides that possess anticonvulsant activity

1 reference

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7 January 2021

[Structural bases of the teratogenic effects of the antiepileptic valproic acid. 2-n-propyl-4-pentenic acid, the first structural analogue with significantly higher teratogenic action than VPA].

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Asymmetric synthesis and enantioselective teratogenicity of 2-n-propyl-4-pentenoic acid (4-en-VPA), an active metabolite of the anticonvulsant drug, valproic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Fetal growth, major malformations, and minor anomalies in infants born to women receiving valproic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

The effects of analogues of valproic acid on seizures induced by pentylenetetrazol and GABA content in brain of mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Variability in level-dose ratio of valproate: monotherapy versus polytherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Spina bifida and in-utero exposure to valproate

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Pharmacological evaluation of various metabolites and analogues of valproic acid. Anticonvulsant and toxic potencies in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Teratogenic effects of sodium valproate in mice and rats at midgestation and at term

1 reference

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7 January 2021

Teratogenic valproic acid concentrations: infusion by implanted minipumps vs conventional injection regimen in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Transfer of valproic acid and its main active unsaturated metabolite to the gestational tissue: correlation with neural tube defect formation in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Species differences in pharmacokinetics and drug teratogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Valproic acid teratogenicity in mice after various administration and phenobarbital-pretreatment regimens: the parent drug and not one of the metabolites assayed is implicated as teratogen

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Pharmacologic evaluation of various metabolites and analogs of valproic acid: teratogenic potencies in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Weak acids may act as teratogens by accumulating in the basic milieu of the early mammalian embryo

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

A new model for embryotoxicity testing: teratogenicity and pharmacokinetics of valproic acid following constant-rate administration in the mouse using human therapeutic drug and metabolite concentrations

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Anticonvulsant activity and embryotoxicity of valproic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Valproic Acid-Induced Neural Tube Defects in Mouse and Human: Aspects of Chirality, Alternative Drug Development, Pharmacokinetics and Possible Mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

The disposition of valproate and its metabolites in the late first trimester and early second trimester of pregnancy in maternal serum, urine, and amniotic fluid: effect of dose, co-medication, and the presence of spina bifida

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Maternal valproic acid and congenital neural tube defects

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

Valproate and birth defects

1 reference

https://api.crossref.org/works/10.1016%2FS0920-1211%2897%2900095-8

7 January 2021

10.1016/S0920-1211(97)00095-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9551843%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference