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P53-dependent and -independent links between DNA-damage, apoptosis and mutation frequency in ES cells
scientific article published on 01 February 1999
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10102623
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10102623%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
title
P53-dependent and -independent links between DNA-damage, apoptosis and mutation frequency in ES cells
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10102623
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10102623%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
main subject
embryonic stem cell
1 reference
based on heuristic
inferred from title
apoptotic process
1 reference
based on heuristic
inferred from title
author name string
Corbet SW
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10102623
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10102623%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Clarke AR
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10102623
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10102623%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Gledhill S
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10102623
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10102623%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Wyllie AH
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10102623
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10102623%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
language of work or name
English
0 references
publication date
1 February 1999
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10102623
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10102623%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10102623
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10102623%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
volume
18
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10102623
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10102623%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
issue
8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10102623
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10102623%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
page(s)
1537-1544
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10102623
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10102623%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.onc.1202436
0 references
cites work
ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High-frequency developmental abnormalities in p53-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 binds single-stranded DNA ends and catalyzes DNA renaturation and strand transfer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth factor modulation of p53-mediated growth arrest versus apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53, mutation frequency and apoptosis in the murine small intestine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thymocyte apoptosis induced by p53-dependent and independent pathways.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spontaneous induction of an homologous robertsonian translocation, Rb(11.11) in a murine embryonic stem cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genomic instability and apoptosis are frequent in p53 deficient young mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor spectrum analysis in p53-mutant mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type p53 is a cell cycle checkpoint determinant following irradiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Radiation-induced apoptosis in F9 teratocarcinoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer. p53, guardian of the genome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 is required for radiation-induced apoptosis in mouse thymocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new mouse embryonic stem cell line with good germ line contribution and gene targeting frequency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proliferating cell nuclear antigen is required for DNA excision repair
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-independent death and p53-induced protection against apoptosis in fibroblasts treated with chemotherapeutic drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clonal lines of teratocarcinoma cells in vitro: differentiation and cytogenetic characteristics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of male embryonal carcinoma cells and their chromosome replication patterns
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The TP53 tumour suppressor gene in colorectal carcinomas. II. Relation to DNA ploidy pattern and clinicopathological variables
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Production of homozygous mutant ES cells with a single targeting construct
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 Protein exhibits 3'-to-5' exonuclease activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of ES cell differentiation by functional and conformational modulation of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 deficiency does not affect the accumulation of point mutations in a transgene target
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specific in vitro binding of p53 to the promoter region of the human mismatch repair gene hMSH2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
All colonies of CHO-K1 cells surviving gamma-irradiation contain non-viable cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 is linked directly to homologous recombination processes via RAD51/RecA protein interaction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear accumulation of p53 in normal human fibroblasts is induced by various cellular stresses which evoke the heat shock response, independently of the cell cycle.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 modulation of TFIIH-associated nucleotide excision repair activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sunburn and p53 in the onset of skin cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202436
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1202436
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10102623
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10102623%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
Dimensions Publication ID
1001007816
0 references
PubMed publication ID
10102623
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10102623
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10102623%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 November 2019
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