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Ras--a versatile cellular switch
scientific article published on 01 August 1998
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Europe PubMed Central
PubMed publication ID
9729716
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9729716%20AND%20SRC:MED&resulttype=core&format=json
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3 December 2019
review article
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title
Ras--a versatile cellular switch
(English)
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Europe PubMed Central
PubMed publication ID
9729716
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3 December 2019
author name string
C Rommel
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1
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PubMed publication ID
9729716
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3 December 2019
E Hafen
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2
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Europe PubMed Central
PubMed publication ID
9729716
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publication date
1 August 1998
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PubMed publication ID
9729716
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3 December 2019
published in
Current Opinion in Genetics & Development
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Europe PubMed Central
PubMed publication ID
9729716
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3 December 2019
volume
8
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Europe PubMed Central
PubMed publication ID
9729716
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9729716%20AND%20SRC:MED&resulttype=core&format=json
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3 December 2019
issue
4
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Europe PubMed Central
PubMed publication ID
9729716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9729716%20AND%20SRC:MED&resulttype=core&format=json
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3 December 2019
page(s)
412-418
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Europe PubMed Central
PubMed publication ID
9729716
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3 December 2019
cites work
Genetics of signal transduction in invertebrates
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
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inferred from DOI database lookup
The Ras signaling pathway in Drosophila
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
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Control and integration of cell signaling pathways during C. elegans vulval development
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
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The GTPase superfamily: a conserved switch for diverse cell functions
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
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Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cooperating oncogenes converge to regulate cyclin/cdk complexes.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Proteins regulating Ras and its relatives
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
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An SH3-SH2-SH3 protein is required for p21Ras1 activation and binds to sevenless and Sos proteins in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
The effector interactions of p21ras
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
How Ras-related proteins talk to their effectors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ins and outs of Raf kinases
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of the Drosophila raf homologue for torso function
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Raf functions downstream of Ras1 in the Sevenless signal transduction pathway
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Control of B cell development by Ras-mediated activation of Raf.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Endothelial apoptosis in Braf-deficient mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
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inferred from DOI database lookup
Nuclear factors in sevenless signalling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
The complexity of Raf-1 regulation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
An intact Raf zinc finger is required for optimal binding to processed Ras and for ras-dependent Raf activation in situ
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
14-3-3 zeta negatively regulates raf-1 activity by interactions with the Raf-1 cysteine-rich domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
14-3-3 and its possible role in co-ordinating multiple signalling pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
The heat shock protein 83 (Hsp83) is required for Raf-mediated signalling in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
KSR, a novel protein kinase required for RAS signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
KSR: a novel player in the RAS pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
KSR modulates signal propagation within the MAPK cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The kinase suppressor of Ras (KSR) modulates growth factor and Ras signaling by uncoupling Elk-1 phosphorylation from MAP kinase activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Kinase suppressor of Ras inhibits the activation of extracellular ligand-regulated (ERK) mitogen-activated protein (MAP) kinase by growth factors, activated Ras, and Ras effectors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Kinase suppressor of Ras is ceramide-activated protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
The structural basis for 14-3-3:phosphopeptide binding specificity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
The activity of D-raf in torso signal transduction is altered by serine substitution, N-terminal deletion, and membrane targeting
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative regulation of Raf activity by binding of 14-3-3 to the amino terminus of Raf in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for Drosophila 14-3-3 zeta in Raf-dependent photoreceptor development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
14-3-3 epsilon positively regulates Ras-mediated signaling in Drosophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcr and Raf form a complex in vivo via 14-3-3 proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
14-3-3 proteins associate with cdc25 phosphatases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphoinositide 3-kinases: a conserved family of signal transducers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PI3K: downstream AKTion blocks apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signalling through the lipid products of phosphoinositide-3-OH kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Type 2 diabetes: when insulin secretion fails to compensate for insulin resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
The activation of phosphatidylinositol 3-kinase by Ras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylinositol-3-OH kinase as a direct target of Ras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple Ras functions can contribute to mammalian cell transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ras-dependent activation of the small GTPase Ral.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rho GTPases and the actin cytoskeleton
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recent advances in understanding signal transduction pathways in worms and flies
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription factors in eye development: a gorgeous mosaic?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ligand-independent activation of the sevenless receptor tyrosine kinase changes the fate of cells in the developing Drosophila eye.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synergistic activation of a Drosophila enhancer by HOM/EXD and DPP signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
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7 January 2021
based on heuristic
inferred from DOI database lookup
MAP kinase pathways in yeast: for mating and more
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0959-437X%2898%2980111-1
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0959-437X(98)80111-1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9729716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9729716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
PubMed publication ID
9729716
1 reference
stated in
Europe PubMed Central
PubMed publication ID
9729716
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9729716%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 December 2019
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