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English
Inactivation of the p53-homologue p73 by the mdm2-oncoprotein
scientific article published on 01 March 1999
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
10321734
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10321734%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
title
Inactivation of the p53-homologue p73 by the mdm2-oncoprotein
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10321734
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10321734%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
author
Matthias Dobbelstein
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10321734
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10321734%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
author name string
S Wienzek
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10321734
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10321734%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
C König
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
10321734
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10321734%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
J Roth
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
10321734
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10321734%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
language of work or name
English
0 references
publication date
1 March 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10321734
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10321734%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PubMed ID
10321734
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10321734%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
volume
18
1 reference
stated in
Europe PubMed Central
PubMed ID
10321734
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10321734%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
page(s)
2101-2106
1 reference
stated in
Europe PubMed Central
PubMed ID
10321734
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10321734%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
issue
12
1 reference
stated in
Europe PubMed Central
PubMed ID
10321734
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10321734%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.onc.1202512
0 references
cites work
p53CP, a putative p53 competing protein that specifically binds to the consensus p53 DNA binding sites: a third member of the p53 family?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mapping of the p53 and mdm-2 interaction domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
First p53 relative may be a new tumor suppressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The MDM2 oncoprotein binds specifically to RNA through its RING finger domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A genetic approach to mapping the p53 binding site in the MDM2 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Physical and functional interaction between wild-type p53 and mdm2 proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 promotes the rapid degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p73 is a simian [correction of human] p53-related protein that can induce apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 stability by Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer. p53, guardian of the genome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53, the cellular gatekeeper for growth and division
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Viral oncoproteins discriminate between p53 and the p53 homolog p73.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amplification of a gene encoding a p53-associated protein in human sarcomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lonely no more: p53 finds its kin in a tumor suppressor haven
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and functional analysis of human p51, which structurally and functionally resembles p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel protein with strong homology to the tumor suppressor p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a novel p53 functional domain that is necessary for efficient growth suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 modulation of TFIIH-associated nucleotide excision repair activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p53-mdm-2 autoregulatory feedback loop
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Non-p53 p53RE binding protein, a human transcription factor functionally analogous to P53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202512
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1202512
1 reference
stated in
Europe PubMed Central
PubMed ID
10321734
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10321734%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
Dimensions Publication ID
1032831783
0 references
PubMed ID
10321734
1 reference
stated in
Europe PubMed Central
PubMed ID
10321734
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10321734%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 December 2019
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