(Q77759334)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891669%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

title

Stereoselective halofantrine and desbutylhalofantrine disposition in the rat: cardiac and plasma concentrations and plasma protein binding (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891669%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference

1 reference

Dion R Brocks

1

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8 December 2019

publication date

1 January 2002

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Biopharmaceutics and Drug Disposition

8 December 2019

published in

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8 December 2019

volume

23

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8 December 2019

issue

1

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8 December 2019

page(s)

9-15

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Resurgent malaria at the millennium: control strategies in crisis

8 December 2019

cites work

1 reference

Clinical pharmacokinetics of halofantrine

21 January 2018

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Cardiac complications of halofantrine: a prospective study of 20 patients

21 January 2018

1 reference

Mechanism of cardiotoxicity of halofantrine

21 January 2018

1 reference

Stereoselective halofantrine disposition and effect: concentration-related QTc prolongation

21 January 2018

1 reference

Pharmacokinetics of halofantrine in the rat: stereoselectivity and interspecies comparisons

21 January 2018

1 reference

Plasma concentrations of the enantiomers of halofantrine and its main metabolite in malaria patients

21 January 2018

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Stereoselective pharmacokinetics of desbutylhalofantrine, a metabolite of halofantrine, in the rat after administration of the racemic metabolite or parent drug

21 January 2018

1 reference

Determination of the free fraction and relative free fraction of drugs strongly bound to plasma proteins

21 January 2018

1 reference

A liquid chromatographic assay for the stereospecific quantitative analysis of halofantrine in human plasma

21 January 2018

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Polar molecular surface properties predict the intestinal absorption of drugs in humans.

21 January 2018

1 reference

The antimalarial drug halofantrine is bound mainly to low and high density lipoproteins in human serum

21 January 2018

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The stereoselective distribution of halofantrine enantiomers within human, dog, and rat plasma lipoproteins

21 January 2018

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Direct determination of the enantiomers of the antimalarial drug halofantrine and its active metabolite N-desbutylhalofantrine in human plasma

21 January 2018

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Chiral chromatographic method to determine the enantiomers of halofantrine and its main chiral desbutyl metabolite in erythrocytes.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/BDD.286

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11891669%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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