(Q77831624)

English

Nortriptyline E-10-hydroxylation in vitro is mediated by human CYP2D6 (high affinity) and CYP3A4 (low affinity): implications for interactions with enzyme-inducing drugs

scientific article published on 01 June 1999

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scholarly article

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8 December 2019

Nortriptyline E-10-hydroxylation in vitro is mediated by human CYP2D6 (high affinity) and CYP3A4 (low affinity): implications for interactions with enzyme-inducing drugs (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10354960%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

David J. Greenblatt

3

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D J Greenblatt

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8 December 2019

Lisa L. von Moltke

2

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L L von Moltke

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8 December 2019

author name string

K Venkatakrishnan

1

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8 December 2019

publication date

1 June 1999

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8 December 2019

The Journal of Clinical Pharmacology

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8 December 2019

39

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8 December 2019

6

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8 December 2019

567-577

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8 December 2019

Nortriptyline and interpersonal psychotherapy as maintenance therapies for recurrent major depression: a randomized controlled trial in patients older than 59 years.

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

E- and Z-10-hydroxylation of nortriptyline: relationship to polymorphic debrisoquine hydroxylation

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Nortriptyline and debrisoquine hydroxylations in Ghanaian and Swedish subjects.

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

10-Hydroxylation of nortriptyline in white persons with 0, 1, 2, 3, and 13 functional CYP2D6 genes

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Stereoselective inhibition of nortriptyline hydroxylation in man by quinidine

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Correlation between nortriptyline and debrisoquine hydroxylation in the human liver

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Time course of enzyme induction in humans: effect of pentobarbital on nortriptyline metabolism

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Concomitant intake of nortriptyline and carbamazepine

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Drug interaction between rifampin and nortriptyline: a case report

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Case report: interaction of rifampin and nortriptyline.

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

The influence of enzyme induction on polymorphic sparteine oxidation

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Determination of cytochrome P450 3A4/5 activity in vivo with dextromethorphan N-demethylation

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Carbamazepine and cigarette smoking induce differentially the metabolism of codeine in man

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Alprazolam metabolism in vitro: studies of human, monkey, mouse, and rat liver microsomes

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations.

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Multiple human cytochromes contribute to biotransformation of dextromethorphan in-vitro: role of CYP2C9, CYP2C19, CYP2D6, and CYP3A

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Midazolam hydroxylation by human liver microsomes in vitro: inhibition by fluoxetine, norfluoxetine, and by azole antifungal agents.

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Five distinct human cytochromes mediate amitriptyline N-demethylation in vitro: dominance of CYP 2C19 and 3A4

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

O- and N-demethylation of venlafaxine in vitro by human liver microsomes and by microsomes from cDNA-transfected cells: effect of metabolic inhibitors and SSRI antidepressants

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Relative quantities of catalytically active CYP 2C9 and 2C19 in human liver microsomes: application of the relative activity factor approach

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

In vitro approaches to predicting drug interactions in vivo.

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Metabolism of the Tricyclic Antidepressant Amitriptyline by cDNA-Expressed Human Cytochrome P450 Enzymes

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Phenobarbital induces the 2-hydroxylation of desipramine

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

The effect of carbamazepine on the 2-hydroxylation of desipramine

1 reference

https://api.crossref.org/works/10.1177%2F00912709922008173

21 January 2018

Identifiers

10.1177/00912709922008173

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10354960%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10354960%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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