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English
Inhibition of E6 induced degradation of p53 is not sufficient for stabilization of p53 protein in cervical tumour derived cell lines
scientific article published on 01 June 1999
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10362351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
title
Inhibition of E6 induced degradation of p53 is not sufficient for stabilization of p53 protein in cervical tumour derived cell lines
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10362351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
author name string
Mantovani F
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10362351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
Banks L
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10362351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
language of work or name
English
0 references
publication date
1 June 1999
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10362351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10362351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
volume
18
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10362351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
issue
22
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10362351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
page(s)
3309-3315
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10362351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.onc.1202688
0 references
cites work
Identification of the HPV-16 E6 protein from transformed mouse cells and human cervical carcinoma cell lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin A and the retinoblastoma gene product complex with a common transcription factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of human-p53-specific monoclonal antibodies and their use in the studies of human p53 expression.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of human papillomavirus type 18 E6 polypeptide in cells derived from human cervical carcinomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Continued expression of HPV-16 E7 protein is required for maintenance of the transformed phenotype of cells co-transformed by HPV-16 plus EJ-ras.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A transforming p53 mutant, which binds DNA, transactivates and induces apoptosis reveals a nuclear:cytoplasmic shuttling defect
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human papillomavirus type 16 E7 associates with a histone H1 kinase and with p107 through sequences necessary for transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
WAF1, a potential mediator of p53 tumor suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mdm2 promotes the rapid degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of the E6-AP regions that direct human papillomavirus E6 binding, association with p53, and ubiquitination of associated proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of p53 stability by Mdm2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Massively parallel sequencing analysis of 68 gastric-type cervical adenocarcinomas reveals mutations in cell cycle-related genes and potentially targetable mutations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel form of Epstein-Barr virus latency in normal B cells in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence-specific transcriptional activation is essential for growth suppression by p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The polyproline region of p53 is required to activate apoptosis but not growth arrest.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription of human papillomavirus type 16 early genes in a cervical cancer and a cancer-derived cell line and identification of the E7 protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Properties of a non-tumorigenic human cervical keratinocyte cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of a p53 polymorphism in the development of human papillomavirus-associated cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a novel p53 functional domain that is necessary for efficient growth suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of human papillomavirus types 16 and 18 E6 proteins with p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1202688
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1202688
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10362351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
Dimensions Publication ID
1044861326
0 references
PubMed publication ID
10362351
1 reference
stated in
Europe PubMed Central
PubMed publication ID
10362351
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10362351%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
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