(Q78232525)

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New Aminocoumarins from the Rare ActinomyceteCatenulispora acidiphilaDSM 44928: Identification, Structure Elucidation, and Heterologous Production

scientific article published on 19 February 2014

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scholarly article

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10.1002/CBIC.201300712

https://api.crossref.org/v1/works/http://dx.doi.org/10.1002/cbic.201300712

12 December 2019

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8 March 2020

New aminocoumarins from the rare actinomycete Catenulispora acidiphila DSM 44928: identification, structure elucidation, and heterologous production (English)

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8 March 2020

Catenulispora acidiphila

1 reference

1 reference

5-[(4,7-dihydroxy-2-oxochromen-3-yl)carbamoyl]-1H-pyrrole-2-carboxylic acid

1 reference

4

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8 March 2020

Stephanie Grond

5

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8 March 2020

6

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8 March 2020

author name string

Judith Zettler

1

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10.1002/CBIC.201300712

https://api.crossref.org/v1/works/http://dx.doi.org/10.1002/cbic.201300712

12 December 2019

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8 March 2020

Haiyang Xia

2

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10.1002/CBIC.201300712

https://api.crossref.org/v1/works/http://dx.doi.org/10.1002/cbic.201300712

12 December 2019

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8 March 2020

Nadja Burkard

3

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10.1002/CBIC.201300712

https://api.crossref.org/v1/works/http://dx.doi.org/10.1002/cbic.201300712

12 December 2019

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8 March 2020

Alexander K Apel

7

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publication date

19 February 2014

2 references

10.1002/CBIC.201300712

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12 December 2019

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8 March 2020

2 references

10.1002/CBIC.201300712

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12 December 2019

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8 March 2020

15

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10.1002/CBIC.201300712

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12 December 2019

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8 March 2020

4

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12 December 2019

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8 March 2020

612-621

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10.1002/CBIC.201300712

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12 December 2019

Europe PubMed Central

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8 March 2020

Reducing the variability of antibiotic production in Streptomyces by cultivation in 24-square deepwell plates

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Probing the Binding of Coumarins and Cyclothialidines to DNA Gyrase†

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A crystal structure of the bifunctional antibiotic simocyclinone D8, bound to DNA gyrase

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Five gene products are required for assembly of the central pyrrole moiety of coumermycin A1.

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Structure-activity relationships of aminocoumarin-type gyrase and topoisomerase IV inhibitors obtained by combinatorial biosynthesis

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Coumarin formation in novobiocin biosynthesis: beta-hydroxylation of the aminoacyl enzyme tyrosyl-S-NovH by a cytochrome P450 NovI

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9 March 2024

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Molecular cloning and sequence analysis of the clorobiocin biosynthetic gene cluster: new insights into the biosynthesis of aminocoumarin antibiotics

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Resistance genes of aminocoumarin producers: two type II topoisomerase genes confer resistance against coumermycin A1 and clorobiocin

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Biosynthesis of novobiocin by Streptomyces niveus

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9 March 2024

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Catenulispora acidiphila gen. nov., sp. nov., a novel, mycelium-forming actinomycete, and proposal of Catenulisporaceae fam. nov.

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9 March 2024

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Inhibition of DNA gyrase and DNA topoisomerase IV of Staphylococcus aureus and Escherichia coli by aminocoumarin antibiotics.

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9 March 2024

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Role of MbtH-like proteins in the adenylation of tyrosine during aminocoumarin and vancomycin biosynthesis.

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9 March 2024

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Simocyclinone D8, an inhibitor of DNA gyrase with a novel mode of action

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Production of 8'-halogenated and 8'-unsubstituted novobiocin derivatives in genetically engineered streptomyces coelicolor strains.

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Lambda red-mediated genetic manipulation of antibiotic-producing Streptomyces.

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DNA topoisomerases and their poisoning by anticancer and antibacterial drugs

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A novel function of novobiocin: disrupting the interaction of HIF 1α and p300/CBP through direct binding to the HIF1α C-terminal activation domain

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9 March 2024

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Identification of the coumermycin A(1) biosynthetic gene cluster of Streptomyces rishiriensis DSM 40489

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An unusual amide synthetase (CouL) from the coumermycin A1 biosynthetic gene cluster from Streptomyces rishiriensis DSM 40489.

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Complete genome sequence of Catenulispora acidiphila type strain (ID 139908).

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Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters.

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Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic

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Bacterial DNA replication enzymes as targets for antibacterial drug discovery

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Herd-level relationship between antimicrobial use and presence or absence of antimicrobial resistance in gram-negative bovine mastitis pathogens on Canadian dairy farms

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Cloning, overexpression, and purification of novobiocic acid synthetase from Streptomyces spheroides NCIMB 11891.

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9 March 2024

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The high-resolution crystal structure of a 24-kDa gyrase B fragment from E. coli complexed with one of the most potent coumarin inhibitors, clorobiocin

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NovJ/NovK catalyze benzylic oxidation of a beta-hydroxyl tyrosyl-S-pantetheinyl enzyme during aminocoumarin ring formation in novobiocin biosynthesis

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Assembly and heterologous expression of the coumermycin A1 gene cluster and production of new derivatives by genetic engineering

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Biosynthesis of simocyclinone D8 in an 18O2-rich atmosphere

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The heat shock protein 90 antagonist novobiocin interacts with a previously unrecognized ATP-binding domain in the carboxyl terminus of the chaperone

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Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891

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Exploiting bacterial DNA gyrase as a drug target: current state and perspectives.

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Identifiers

10.1002/CBIC.201300712

2 references

10.1002/CBIC.201300712

https://api.crossref.org/v1/works/http://dx.doi.org/10.1002/cbic.201300712

12 December 2019

Europe PubMed Central

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8 March 2020

PubMed publication ID

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Europe PubMed Central

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8 March 2020

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