(Q34214929)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904817%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

2 references

29 May 2020

11 September 2020

Exploiting bacterial DNA gyrase as a drug target: current state and perspectives (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904817%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

2 August 2019

1 reference

2 October 2019

1 reference

2 November 2019

1 reference

11 September 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904817%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Anthony Maxwell

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904817%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

author name string

Shantanu Karkare

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904817%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

language of work or name

English

0 references

publication date

9 September 2011

1 reference

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Applied Microbiology and Biotechnology

12 February 2020

1 November 2011

2 references

29 May 2020

11 September 2020

7 references

22 June 2019

2 August 2019

2 October 2019

2 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904817%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

29 May 2020

11 September 2020

92

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904817%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

page(s)

479-497

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904817%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904817%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s00253-011-3557-z

12 February 2020

exact match

0 references

cites work

Vibrio cholerae ParE2 poisons DNA gyrase via a mechanism distinct from other gyrase inhibitors

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Structural and biochemical analysis of the pentapeptide repeat protein EfsQnr, a potent DNA gyrase inhibitor

5 July 2018

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Solution structures of DNA-bound gyrase

5 July 2018

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Structural Insights into the Quinolone Resistance Mechanism of Mycobacterium tuberculosis DNA Gyrase

5 July 2018

1 reference

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Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance

5 July 2018

1 reference

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Type IIA topoisomerase inhibition by a new class of antibacterial agents

5 July 2018

1 reference

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A domain insertion in Escherichia coli GyrB adopts a novel fold that plays a critical role in gyrase function

5 July 2018

1 reference

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Structural basis of gate-DNA breakage and resealing by type II topoisomerases

5 July 2018

1 reference

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DNA topoisomerases and their poisoning by anticancer and antibacterial drugs

5 July 2018

1 reference

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How antibiotics kill bacteria: from targets to networks

5 July 2018

1 reference

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Twisting of the DNA-binding surface by a beta-strand-bearing proline modulates DNA gyrase activity.

5 July 2018

1 reference

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A Conserved Mode of Protein Recognition and Binding in a ParD−ParE Toxin−Antitoxin Complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Simocyclinone D8 turns on against Gram-negative bacteria in a clinical setting.

5 July 2018

1 reference

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A crystal structure of the bifunctional antibiotic simocyclinone D8, bound to DNA gyrase

5 July 2018

1 reference

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Crystal structure of the DNA gyrase GyrA N-terminal domain fromMycobacterium tuberculosis

5 July 2018

1 reference

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The aminocoumarins: biosynthesis and biology.

5 July 2018

1 reference

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Quinolones: action and resistance updated

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Rejuvenation of CcdB-poisoned gyrase by an intrinsically disordered protein domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Crystal structure of DNA gyrase B' domain sheds lights on the mechanism for T-segment navigation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

A journey in the world of DNA rings and beyond

5 July 2018

1 reference

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Genetic engineering of antibiotic biosynthesis for the generation of new aminocoumarins.

5 July 2018

1 reference

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Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases

5 July 2018

1 reference

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In vivo and in vitro patterns of the activity of simocyclinone D8, an angucyclinone antibiotic from Streptomyces antibioticus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Effects of magnesium and related divalent metal ions in topoisomerase structure and function.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Anti-proliferative effects of simocyclinone D8 (SD8), a novel catalytic inhibitor of topoisomerase II.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Moonlighting function of glutamate racemase from Mycobacterium tuberculosis: racemization and DNA gyrase inhibition are two independent activities of the enzyme

5 July 2018

1 reference

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DNA topoisomerases: harnessing and constraining energy to govern chromosome topology

5 July 2018

1 reference

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Clerocidin selectively modifies the gyrase-DNA gate to induce irreversible and reversible DNA damage

5 July 2018

1 reference

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Mechanism of action of the antibiotic NXL101, a novel nonfluoroquinolone inhibitor of bacterial type II topoisomerases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

YacG from Escherichia coli is a specific endogenous inhibitor of DNA gyrase

5 July 2018

1 reference

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Recent advances in bacterial topoisomerase inhibitors

5 July 2018

1 reference

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Discovery and characterization of QPT-1, the progenitor of a new class of bacterial topoisomerase inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Inhibition of DNA gyrase activity by Mycobacterium smegmatis MurI.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

A common mechanism of cellular death induced by bactericidal antibiotics

5 July 2018

1 reference

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Discovery and development of ATPase inhibitors of DNA gyrase as antibacterial agents

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

The solution structure of ParD, the antidote of the ParDE toxin-antitoxin module, provides the structural basis for DNA and toxin binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Energy coupling in type II topoisomerases: why do they hydrolyze ATP?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Thirty years of Escherichia coli DNA gyrase: from in vivo function to single-molecule mechanism.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Exploring DNA topoisomerases as targets of novel therapeutic agents in the treatment of infectious diseases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

The action of the bacterial toxin, microcin B17, on DNA gyrase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

In vitro and in vivo activities of PD 0305970 and PD 0326448, new bacterial gyrase/topoisomerase inhibitors with potent antibacterial activities versus multidrug-resistant gram-positive and fastidious organism groups

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Glutamate racemase from Mycobacterium tuberculosis inhibits DNA gyrase by affecting its DNA-binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Structural basis for nucleic acid and toxin recognition of the bacterial antitoxin CcdA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

A strand-passage conformation of DNA gyrase is required to allow the bacterial toxin, CcdB, to access its binding site

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Structure-activity relationships of aminocoumarin-type gyrase and topoisomerase IV inhibitors obtained by combinatorial biosynthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Pentapeptide repeat proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Interaction of the plasmid-encoded quinolone resistance protein QnrA with Escherichia coli topoisomerase IV

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

A fluoroquinolone resistance protein from Mycobacterium tuberculosis that mimics DNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Simocyclinone D8, an inhibitor of DNA gyrase with a novel mode of action

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Interaction of the plasmid-encoded quinolone resistance protein Qnr with Escherichia coli DNA gyrase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

The C-terminal domain of DNA gyrase A adopts a DNA-bending beta-pinwheel fold

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

New antibacterial agents derived from the DNA gyrase inhibitor cyclothialidine

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Clerocidin alkylates DNA through its epoxide function: evidence for a fine tuned mechanism of action.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Catalytic topoisomerase II inhibitors in cancer therapy.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Differences in effects on DNA gyrase activity between two glutamate racemases of Bacillus subtilis, the poly-gamma-glutamate synthesis-linking Glr enzyme and the YrpC (MurI) isozyme

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

The quinolones: decades of development and use

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Active-site residues of Escherichia coli DNA gyrase required in coupling ATP hydrolysis to DNA supercoiling and amino acid substitutions leading to novobiocin resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

The ATP-binding site of type II topoisomerases as a target for antibacterial drugs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Glutamate racemase is an endogenous DNA gyrase inhibitor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

NMR structure of the Escherichia coli protein YacG: a novel sequence motif in the zinc-finger family of proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tü 6040.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

DNA gyrase interaction with coumarin-based inhibitors: the role of the hydroxybenzoate isopentenyl moiety and the 5'-methyl group of the noviose

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Quinolone-binding pocket of DNA gyrase: role of GyrB.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Biosynthetic gene cluster of simocyclinone, a natural multihybrid antibiotic

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Crystal structure of the Escherichia coli SbmC protein that protects cells from the DNA replication inhibitor microcin B17

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Mechanism of plasmid-mediated quinolone resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Quinolones: a comprehensive review

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

An open conformation of the Thermus thermophilus gyrase B ATP-binding domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

GyrI: a counter-defensive strategy against proteinaceous inhibitors of DNA gyrase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

The topoisomerase II poison clerocidin alkylates non-paired guanines of DNA: implications for irreversible stimulation of DNA cleavage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

DNA topoisomerases: structure, function, and mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Type II topoisomerases as targets for quinolone antibacterials: turning Dr. Jekyll into Mr. Hyde

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

The interaction of drugs with DNA gyrase: a model for the molecular basis of quinolone action

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

New classification and update on the quinolone antibiotics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Dimerization of Escherichia coli DNA-gyrase B provides a structural mechanism for activating the ATPase catalytic center

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Crystal structure of CcdB, a topoisomerase poison from E. coli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Quinolone resistance from a transferable plasmid.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Crystal structure of the breakage-reunion domain of DNA gyrase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

The entropic penalty of ordered water accounts for weaker binding of the antibiotic novobiocin to a resistant mutant of DNA gyrase: a thermodynamic and crystallographic study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

DNA gyrase can cleave short DNA fragments in the presence of quinolone drugs

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

The high-resolution crystal structure of a 24-kDa gyrase B fragment from E. coli complexed with one of the most potent coumarin inhibitors, clorobiocin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Targeting of DNA gyrase in Streptococcus pneumoniae by sparfloxacin: selective targeting of gyrase or topoisomerase IV by quinolones.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

In the presence of subunit A inhibitors DNA gyrase cleaves DNA fragments as short as 20 bp at specific sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

GyrB mutations in Staphylococcus aureus strains resistant to cyclothialidine, coumermycin, and novobiocin.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Differential regulation of the mcb and emr operons of Escherichia coli: role of mcb in multidrug resistance.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Mode of action of GR122222X, a novel inhibitor of bacterial DNA gyrase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Molecular mechanisms of drug inhibition of DNA gyrase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

At least two separate gene clusters are involved in albicidin production by Xanthomonas albilineans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

The nature of inhibition of DNA gyrase by the coumarins and the cyclothialidines revealed by X-ray crystallography

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Plasmid RK2 toxin protein ParE: purification and interaction with the ParD antitoxin protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Structure and mechanism of DNA topoisomerase II

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

The F plasmid CcdB protein induces efficient ATP-dependent DNA cleavage by gyrase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Evidence for a conformational change in the DNA gyrase-DNA complex from hydroxyl radical footprinting

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

gyrB mutations in coumermycin A1-resistant Borrelia burgdorferi

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Posttranslational modifications in microcin B17 define an additional class of DNA gyrase inhibitor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Biological characterization of cyclothialidine, a new DNA gyrase inhibitor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Cyclothialidine and its congeners: a new class of DNA gyrase inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Mechanism of inhibition of DNA gyrase by cyclothialidine, a novel DNA gyrase inhibitor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

The intrinsic ATPase of DNA gyrase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Control of cell division by sex factor F in Escherichia coli. II. Identification of genes for inhibitor protein and trigger protein on the 42.84-43.6 F segment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Mechanism of action of cinodine, a glycocinnamoylspermidine antibiotic

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Microcin B17 blocks DNA replication and induces the SOS system in Escherichia coli.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

The export of the DNA replication inhibitor Microcin B17 provides immunity for the host cell

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Cloning and mapping of the genetic determinants for microcin B17 production and immunity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

In vitro inhibition of bacterial DNA gyrase by cinodine, a glycocinnamoylspermidine antibiotic

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

The peptide antibiotic microcin B17 induces double-strand cleavage of DNA mediated by E. coli DNA gyrase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Mutations in DNA gyrase result in novobiocin resistance in halophilic archaebacteria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

DNA gyrase: structure and function.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Quinolone resistance-determining region in the DNA gyrase gyrB gene of Escherichia coli

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

An unusual mechanism for resistance to the antibiotic coumermycin A1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Crystal structure of an N-terminal fragment of the DNA gyrase B protein.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Cell killing by the F plasmid CcdB protein involves poisoning of DNA-topoisomerase II complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

gyrB mutations which confer coumarin resistance also affect DNA supercoiling and ATP hydrolysis by Escherichia coli DNA gyrase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Control of segregation of chromosomal DNA by sex factor F in Escherichia coli. Mutants of DNA gyrase subunit A suppress letD (ccdB) product growth inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Novobiocin and coumermycin inhibit DNA supercoiling catalyzed by DNA gyrase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Glycocinnamoylspermidines, a new class of antibiotics. II. Isolation, physiocochemical and biological properties of LL-BM123beta, gamma1 and gamma2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Energy coupling in DNA gyrase and the mechanism of action of novobiocin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Nalidixic acid resistance: A second genetic character involved in DNA gyrase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

DNA gyrase: subunit structure and ATPase activity of the purified enzyme

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

A new family of low molecular weight antibiotics from enterobacteria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Chromosomally encoded gyrase inhibitor GyrI protects Escherichia coli against DNA-damaging agents

5 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3557-Z

Small-angle X-ray scattering reveals the solution structure of the full-length DNA gyrase a subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3557-Z

Molecular basis of gyrase poisoning by the addiction toxin CcdB.

21 January 2018

1 reference

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Cloning and primary structure of Staphylococcus aureus DNA topoisomerase IV: a primary target of fluoroquinolones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3557-Z

The phytotoxin albicidin is a novel inhibitor of DNA gyrase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3557-Z

DNA gyrase from the albicidin producer Xanthomonas albilineans has multiple-antibiotic-resistance and unusual enzymatic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3557-Z

The antibiotic microcin B17 is a DNA gyrase poison: characterisation of the mode of inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3557-Z

Nucleotide binding to DNA gyrase causes loss of DNA wrap

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3557-Z

ParE toxin encoded by the broad-host-range plasmid RK2 is an inhibitor of Escherichia coli gyrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3557-Z

The action of the bacterial toxin microcin B17. Insight into the cleavage-religation reaction of DNA gyrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3557-Z

Evidence for the role of DNA strand passage in the mechanism of action of microcin B17 on DNA gyrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3557-Z

Clerocidin interacts with the cleavage complex of Streptococcus pneumoniae topoisomerase IV to induce selective irreversible DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3557-Z

Mapping simocyclinone D8 interaction with DNA gyrase: evidence for a new binding site on GyrB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3557-Z

Total synthesis of microcin B17 via a fragment condensation approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3557-Z

Advances in structure-based drug design of novel bacterial topoisomerase inhibitors.

21 January 2018

1 reference

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Locking the DNA gate of DNA gyrase: investigating the effects on DNA cleavage and ATP hydrolysis.

21 January 2018

1 reference

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Probing the two-gate mechanism of DNA gyrase using cysteine cross-linking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00253-011-3557-Z

1,8-NAPHTHYRIDINE DERIVATIVES. A NEW CLASS OF CHEMOTHERAPEUTIC AGENTS.

21 January 2018

1 reference

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Simocyclinones, novel cytostatic angucyclinone antibiotics produced by Streptomyces antibioticus Tü 6040. I. Taxonomy, fermentation, isolation and biological activities.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189412

Characterization of a cinodine-resistant mutant of Escherichia coli.

28 October 2018

1 reference

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Preliminary characterization of an antibiotic produced by Xanthomonas albilineans which inhibits DNA synthesis in Escherichia coli.

28 October 2018

1 reference

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Probing the Binding of Coumarins and Cyclothialidines to DNA Gyrase†

28 October 2018

1 reference

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The interaction of DNA gyrase with the bacterial toxin CcdB: evidence for the existence of two gyrase-CcdB complexes 1 1Edited by I. B. Holland

21 January 2018

1 reference

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Mass Spectrometry Reveals That the Antibiotic Simocyclinone D8 Binds to DNA Gyrase in a “Bent-Over” Conformation: Evidence of Positive Cooperativity in Binding

21 January 2018

1 reference

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Glycocinnamoylspermidines, a new class of antibiotics. I. Description and fermentation of the organism producing the LL-BM123 antibiotics

21 January 2018

1 reference

12 December 2020

Type II DNA topoisomerases: enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break

1 reference

12 December 2020

The DNA replication inhibitor microcin B17 is a forty-three-amino-acid protein containing sixty percent glycine

1 reference

12 December 2020

The interaction of the F plasmid killer protein, CcdB, with DNA gyrase: induction of DNA cleavage and blocking of transcription 1 1J. Karn

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12 December 2020

Identification of DNA gyrase inhibitor (GyrI) in Escherichia coli

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12 December 2020

DNA transport by a type II DNA topoisomerase: evidence in favor of a two-gate mechanism

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12 December 2020

The 24 kDa N-terminal sub-domain of the DNA gyrase B protein binds coumarin drugs

1 reference

12 December 2020

Characterization of the binding site for cyclothialidine on the B subunit of DNA gyrase

1 reference

12 December 2020

Modular Structure of the Full-Length DNA Gyrase B Subunit Revealed by Small-Angle X-Ray Scattering

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12 December 2020

Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: synthesis and preliminary SAR analysis

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12 December 2020

Tetrahydroindazole inhibitors of bacterial type II topoisomerases. Part 2: SAR development and potency against multidrug-resistant strains

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12 December 2020

Peptides based on CcdB protein as novel inhibitors of bacterial topoisomerases

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12 December 2020

Microbial growth and production kinetics of Streptomyces antibioticus Tü 6040

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12 December 2020

Induction of a heat-stable topoisomerase II-DNA cleavable complex by nonintercalative terpenoides, terpentecin and clerocidin

1 reference

12 December 2020

The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases

1 reference

12 December 2020

Clerocidin, a terpenoid antibiotic, inhibits bacterial DNA gyrase

1 reference

12 December 2020

sbmC, a stationary-phase induced SOS Escherichia coli gene, whose product protects cells from the DNA replication inhibitor microcin B17

1 reference

12 December 2020

Glycocinnamoylspermidines, a new class of antibiotics. II. Isolation, physicochemical and biological properties of LL-BM123.BETA.,.GAMMA.1 and .GAMMA.2.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.31.398

Identifiers

DOI

10.1007/S00253-011-3557-Z

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904817%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21904817%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference