(Q78353663)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12372616%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

title

Study of the cytotoxic effect of a peptidic inhibitor of the p53-hdm2 interaction in tumor cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12372616%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

author name string

Patrick Chène

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12372616%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Jean Fuchs

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12372616%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Ilaria Carena

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12372616%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Pascal Furet

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12372616%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

Carlos García-Echeverría

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12372616%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

publication date

1 October 2002

1 reference

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13 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12372616%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

volume

529

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12372616%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

page(s)

293-297

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12372616%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

issue

2-3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12372616%20AND%20SRC:MED&resulttype=core&format=json

Functions of the MDM2 oncoprotein

13 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

The p53-mdm2 autoregulatory feedback loop: a paradigm for the regulation of growth control by p53?

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

p19ARF links the tumour suppressor p53 to Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

Nucleolar Arf sequesters Mdm2 and activates p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

The MDM2 gene amplification database

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

Discovery of potent antagonists of the interaction between human double minute 2 and tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

C-terminal truncation of the retinoblastoma gene product leads to functional inactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

Genetic determinants of p53-induced apoptosis and growth arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

The proliferation of normal human fibroblasts is dependent upon negative regulation of p53 function by mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

Ubiquitous induction of p53 in tumor cells by antisense inhibition of MDM2 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2802%2903362-8

10.1016/S0014-5793(02)03362-8

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12372616%20AND%20SRC:MED&resulttype=core&format=json

13 December 2019

1 reference