(Q79176169)

English

The D246V mutant of DNA polymerase beta misincorporates nucleotides: evidence for a role for the flexible loop in DNA positioning within the active site

scientific article published on 16 October 2003

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563842%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

The D246V mutant of DNA polymerase beta misincorporates nucleotides: evidence for a role for the flexible loop in DNA positioning within the active site (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563842%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Joann B. Sweasy

3

object named as

Joann B Sweasy

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563842%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

author name string

Shibani Dalal

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563842%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Jessica L Kosa

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563842%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

language of work or name

0 references

publication date

16 October 2003

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563842%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563842%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

279

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563842%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563842%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

577-584

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563842%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Instability and decay of the primary structure of DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

The base excision repair pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Requirement of mammalian DNA polymerase-beta in base-excision repair.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Variant forms of DNA polymerase beta in primary lung carcinomas.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Nucleotide excision repair DNA synthesis by excess DNA polymerase beta: a potential source of genetic instability in cancer cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

DNA polymerase beta expression differences in selected human tumors and cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Evidence for a role for DNA polymerase beta in mammalian meiosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

A mechanism for all polymerases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Base substitution specificity of DNA polymerase beta depends on interactions in the DNA minor groove

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Increased activity and fidelity of DNA polymerase beta on single-nucleotide gapped DNA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Selective action of 4'-azidothymidine triphosphate on reverse transcriptase of human immunodeficiency virus type 1 and human DNA polymerases alpha and beta.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

3'-Azido-3'-deoxythymidine-resistant mutants of DNA polymerase beta identified by in vivo selection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

The E249K mutator mutant of DNA polymerase beta extends mispaired termini

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Involvement of phenylalanine 272 of DNA polymerase beta in discriminating between correct and incorrect deoxynucleoside triphosphates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Conformational coupling in DNA polymerase fidelity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

A genetic system to identify DNA polymerase beta mutator mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

DNA polymerase beta: pre-steady-state kinetic analysis and roles of arginine-283 in catalysis and fidelity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Passing the baton in base excision repair

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

The mutational specificity of the Dbh lesion bypass polymerase and its implications

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Low fidelity DNA synthesis by a y family DNA polymerase due to misalignment in the active site.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Enzyme-DNA interactions required for efficient nucleotide incorporation and discrimination in human DNA polymerase beta.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase beta. Implication for the identity of the rate-limiting conformational change

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Y265H mutator mutant of DNA polymerase beta. Proper teometric alignment is critical for fidelity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M309607200

21 January 2018

Identifiers

10.1074/JBC.M309607200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563842%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14563842%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q79176169&oldid=1783512199"