(Q79236261)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14592488%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

title

Synthesis of novel fluorescent probes for the molecular chaperone Hsp90 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14592488%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

27 March 2024

pharmaceutical science

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

27 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

27 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

27 March 2024

author name string

Laura Llauger-Bufi

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14592488%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Henri Huezo

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14592488%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Neal Rosen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14592488%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Gabriela Chiosis

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14592488%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

Sara J. Felts

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14592488

27 March 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14592488

27 March 2024

publication date

1 November 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14592488%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

17 November 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14592488

full work available at URL

27 March 2024

https://api.elsevier.com/content/article/PII:S0960894X03009351?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

https://api.elsevier.com/content/article/PII:S0960894X03009351?httpAccept=text/plain

27 March 2024

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

Bioorganic & Medicinal Chemistry Letters

27 March 2024

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14592488%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14592488%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14592488%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

page(s)

3975-3978

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14592488%20AND%20SRC:MED&resulttype=core&format=json

The Hsp90 complex--a super-chaperone machine as a novel drug target

20 December 2019

cites work

1

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

Hsp90 & Co. - a holding for folding

27 March 2024

2

1 reference

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Recent Advances in the Study of hsp90 Structure and Mechanism of Action

27 March 2024

3

1 reference

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Hsp90 inhibitors as novel cancer chemotherapeutic agents

27 March 2024

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1 reference

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HSP90 as a new therapeutic target for cancer therapy: the story unfolds

27 March 2024

5

1 reference

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Crystal structure of an Hsp90-geldanamycin complex: targeting of a protein chaperone by an antitumor agent

27 March 2024

6

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin

27 March 2024

7

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

27 March 2024

8

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis

27 March 2024

9

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

The ATPase cycle of Hsp90 drives a molecular 'clamp' via transient dimerization of the N-terminal domains

27 March 2024

10

1 reference

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Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

27 March 2024

11

1 reference

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Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90

27 March 2024

12

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

Development of a purine-scaffold novel class of Hsp90 binders that inhibit the proliferation of cancer cells and induce the degradation of Her2 tyrosine kinase

27 March 2024

13

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin

27 March 2024

14

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

Regulation of Hsp90 ATPase activity by tetratricopeptide repeat (TPR)-domain co-chaperones

27 March 2024

15

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo

27 March 2024

16

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis

27 March 2024

17

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

Coordinated ATP hydrolysis by the Hsp90 dimer

27 March 2024

18

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

C-terminal regions of Hsp90 are important for trapping the nucleotide during the ATPase cycle

27 March 2024

19

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

Filter binding assay for the geldanamycin–heat shock protein 90 interaction

27 March 2024

20

1 reference

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Geldanamycin as a potential anti-cancer agent: its molecular target and biochemical activity

27 March 2024

22

1 reference

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Inhibition of the oncogene product p185erbB-2 in vitro and in vivo by geldanamycin and dihydrogeldanamycin derivatives

27 March 2024

23

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

erbB-2 oncogene inhibition by geldanamycin derivatives: synthesis, mechanism of action, and structure-activity relationships

27 March 2024

24

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin

27 March 2024

25

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells

27 March 2024

26

1 reference

https://api.crossref.org/works/10.1016/J.BMCL.2003.08.065

27 March 2024

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14592488%20AND%20SRC:MED&resulttype=core&format=json

20 December 2019

1 reference