(Q79295172)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14618582%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

(-)-FR182877 is a potent and selective inhibitor of carboxylesterase-1 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14618582%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

(−)‐FR182877 Is a Potent and Selective Inhibitor of Carboxylesterase‐1 (English)

1 reference

https://api.crossref.org/works/10.1002/ANIE.200352576

2 April 2024

4

Benjamin F Cravatt

1 reference

21 December 2019

3

Erik J. Sorensen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14618582

2 April 2024

author name string

Gregory C. Adam

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14618582

2 April 2024

Christopher D. Vanderwal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14618582

2 April 2024

Benjamin F. Cravatt

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14618582

2 April 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14618582

2 April 2024

publication date

1 November 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14618582%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

17 November 2003

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14618582

full work available at URL

2 April 2024

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fanie.200352576

1 reference

https://api.crossref.org/works/10.1002/ANIE.200352576

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.200352576

2 April 2024

1 reference

https://api.crossref.org/works/10.1002/ANIE.200352576

Angewandte Chemie International Edition

2 April 2024

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14618582%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

volume

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14618582%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

issue

44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14618582%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

page(s)

5480-5484

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14618582%20AND%20SRC:MED&resulttype=core&format=json

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

21 December 2019

cites work

1

1 reference

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Molecular mechanisms underlying inhibition of protein phosphatases by marine toxins

2 April 2024

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Deacetylase enzymes: biological functions and the use of small-molecule inhibitors

2 April 2024

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Structure of human methionine aminopeptidase-2 complexed with fumagillin

2 April 2024

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In vivo and in vitro binding of microcystin to protein phosphatases 1 and 2A.

2 April 2024

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Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

2 April 2024

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A new antimitotic substance, FR182877. I. Taxonomy, fermentation, isolation, physico-chemical properties and biological activities.

2 April 2024

9

1 reference

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A new antimitotic substance, FR182877. II. The mechanism of action

2 April 2024

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A new antimitotic substance, FR182877. III. Structure determination

2 April 2024

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Postulated biogenesis of WS9885B and progress toward an enantioselective synthesis

2 April 2024

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Intramolecular allenolate acylations in studies toward a synthesis of FR182877

2 April 2024

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A synthesis of (+)-FR182877, featuring tandem transannular Diels-Alder reactions inspired by a postulated biogenesis

2 April 2024

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1 reference

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An Enantioselective Synthesis of FR182877 Provides a Chemical Rationalization of Its Structure and Affords Multigram Quantities of Its Direct Precursor

2 April 2024

15

1 reference

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A cascade cycloaddition strategy leading to the total synthesis of (-)-FR182877

2 April 2024

17

1 reference

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A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

2 April 2024

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Trifunctional chemical probes for the consolidated detection and identification of enzyme activities from complex proteomes

2 April 2024

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Rat serum carboxylesterase. Cloning, expression, regulation, and evidence of secretion from liver

2 April 2024

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American Journal of Physiology

2 April 2024

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275

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Krishnasamy S.

1998

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Human carboxylesterase 1: from drug metabolism to drug discovery

2 April 2024

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Proteomic profiling of mechanistically distinct enzyme classes using a common chemotype

2 April 2024

28

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Regulation of two rat liver microsomal carboxylesterase isozymes: species differences, tissue distribution, and the effects of age, sex, and xenobiotic treatment of rats

2 April 2024

29

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Direct visualization of serine hydrolase activities in complex proteomes using fluorescent active site-directed probes

2 April 2024

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Enzyme activity profiles of the secreted and membrane proteome that depict cancer cell invasiveness

2 April 2024

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Profiling serine hydrolase activities in complex proteomes

2 April 2024

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Discovering potent and selective reversible inhibitors of enzymes in complex proteomes

2 April 2024

33

1 reference

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Proteome analysis of hepatocellular carcinoma

2 April 2024

35

1 reference

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Orlistat: its current status as an anti-obesity drug

2 April 2024

36

1 reference

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Protease inhibitors: current status and future prospects

2 April 2024

37

1 reference

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Architectural self-construction in nature and chemical synthesis

2 April 2024

38

1 reference

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2 April 2024

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14618582%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference