(Q79764631)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18975059%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Pharmacokinetic and pharmacodynamic modeling of a humanized anti-IL-13 antibody in naive and Ascaris-challenged cynomolgus monkeys (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18975059%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

1 reference

Yulia Vugmeyster

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18975059%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Xianbin Tian

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18975059%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Pamela Szklut

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18975059%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Marion Kasaian

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18975059%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Xin Xu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18975059%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

publication date

31 October 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18975059%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

published in

Pharmaceutical Research

1 reference

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25 December 2019

volume

26

1 reference

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25 December 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18975059%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

page(s)

306-315

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18975059%20AND%20SRC:MED&resulttype=core&format=json

The use of TNF-alpha blocking agents in rheumatoid arthritis: an update

25 December 2019

cites work

1 reference

12 December 2020

Therapeutic Dosing with Anti-Interleukin-13 Monoclonal Antibody Inhibits Asthma Progression in Mice

1 reference

12 December 2020

IL-13 blockade reduces lung inflammation after Ascaris suum challenge in cynomolgus monkeys

1 reference

12 December 2020

Interleukin-13 levels in serum from patients with Hodgkin disease and healthy volunteers

1 reference

12 December 2020

Preclinical pharmacokinetics, interspecies scaling, and tissue distribution of a humanized monoclonal antibody against vascular endothelial growth factor.

1 reference

12 December 2020

General pharmacokinetic model for drugs exhibiting target-mediated drug disposition

1 reference

12 December 2020

Mechanism-based pharmacokinetic-pharmacodynamic modeling: biophase distribution, receptor theory, and dynamical systems analysis

1 reference

12 December 2020

Phase Ib trial of intravenous recombinant humanized monoclonal antibody to vascular endothelial growth factor in combination with chemotherapy in patients with advanced cancer: pharmacologic and long-term safety data

1 reference

12 December 2020

Interleukin-13 neutralization by two distinct receptor blocking mechanisms reduces immunoglobulin E responses and lung inflammation in cynomolgus monkeys

1 reference

12 December 2020

Interleukin-13 in asthma pathogenesis

1 reference

12 December 2020

Pharmacokinetics/pharmacodynamics of nondepleting anti-CD4 monoclonal antibody (TRX1) in healthy human volunteers

1 reference

12 December 2020

Immunoaffinity capillary electrophoresis: determination of binding constant and stoichiometry for antibody-antigen interaction.

1 reference

12 December 2020

Kinetic analysis of the interleukin-13 receptor complex

1 reference

12 December 2020

New treatments for SLE: cell-depleting and anti-cytokine therapies

1 reference

12 December 2020

Cytokine-directed therapy in asthma

1 reference

12 December 2020

Biology and therapeutic potential of the interleukin-4/interleukin-13 signaling pathway in asthma

1 reference

12 December 2020

Requirement for IL-13 independently of IL-4 in experimental asthma

1 reference

12 December 2020

Interleukin-13: central mediator of allergic asthma

1 reference

12 December 2020

Model and Simulation of Multivalent Binding to Fixed Ligands

1 reference

12 December 2020

The role of IL-13 in established allergic airway disease.

1 reference

12 December 2020

Genetics of IL-13 and functional relevance of IL-13 variants

1 reference

12 December 2020

Effects of anticytokine therapy in a mouse model of chronic asthma

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of a humanized monoclonal antibody to factor IX in cynomolgus monkeys

1 reference

12 December 2020

Pharmacokinetics and pharmacodynamics of SB-240563, a humanized monoclonal antibody directed to human interleukin-5, in monkeys.

1 reference

12 December 2020

Cytokine traps: multi-component, high-affinity blockers of cytokine action

1 reference

12 December 2020

Modulation of cytokine production by intravenous immunoglobulin in patients with enterovirus 71-associated brainstem encephalitis.

1 reference

12 December 2020

A mechanism-based binding model for the population pharmacokinetics and pharmacodynamics of omalizumab.

1 reference

12 December 2020

Regulation of cytokines, cytokine inhibitors, and acute-phase proteins following anti-TNF-alpha therapy in rheumatoid arthritis

1 reference

12 December 2020

Preclinical pharmacokinetics, interspecies scaling, and tissue distribution of humanized monoclonal anti-IL-13 antibodies with different IL-13 neutralization mechanisms

1 reference

12 December 2020

Pharmacokinetic and pharmacodynamic modeling of humanized anti-factor IX antibody (SB 249417) in humans.

1 reference

12 December 2020

A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease

1 reference

12 December 2020

IL-13 regulates the immune response to inhaled antigens

1 reference

12 December 2020

Humanization of a recombinant monoclonal antibody to produce a therapeutic HER dimerization inhibitor, pertuzumab

1 reference

12 December 2020

10.1007/S11095-008-9739-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18975059%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference