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Rational combinations of siRNAs targeting Plk1 with breast cancer drugs
scientific article published on 19 March 2007
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
17369857
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17369857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
title
Rational combinations of siRNAs targeting Plk1 with breast cancer drugs
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
17369857
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17369857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
main subject
breast cancer
1 reference
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inferred from title
author name string
B Spänkuch
series ordinal
1
1 reference
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Europe PubMed Central
PubMed ID
17369857
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17369857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
E Kurunci-Csacsko
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
17369857
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17369857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
M Kaufmann
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
17369857
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17369857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
K Strebhardt
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
17369857
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17369857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
publication date
19 March 2007
1 reference
stated in
Europe PubMed Central
PubMed ID
17369857
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17369857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
published in
Oncogene
1 reference
stated in
Europe PubMed Central
PubMed ID
17369857
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17369857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
volume
26
1 reference
stated in
Europe PubMed Central
PubMed ID
17369857
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17369857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
page(s)
5793-5807
1 reference
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Europe PubMed Central
PubMed ID
17369857
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17369857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
issue
39
1 reference
stated in
Europe PubMed Central
PubMed ID
17369857
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17369857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
exact match
https://scigraph.springernature.com/pub.10.1038/sj.onc.1210355
0 references
cites work
Polo-like kinase (Plk) 1: a novel target for the treatment of prostate cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
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Polo-like kinase 1 (Plk1) inhibits p53 function by physical interaction and phosphorylation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
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inferred from DOI database lookup
Polo-like kinases and the orchestration of cell division
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
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p27 as a target for cancer therapeutics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A multistep model for paclitaxel-induced apoptosis in human breast cancer cell lines
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
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inferred from DOI database lookup
A crucial test
1 reference
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Crossref
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7 January 2021
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Enhanced drug resistance in cells coexpressing ErbB2 with EGF receptor or ErbB3.
1 reference
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Crossref
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7 January 2021
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Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitory Fc receptors modulate in vivo cytotoxicity against tumor targets
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
based on heuristic
inferred from DOI database lookup
Platinum-taxane combinations in metastatic breast cancer: an evolving role in the era of molecularly targeted therapy
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
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A potential synergistic anticancer effect of paclitaxel and amifostine on endometrial cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
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HER2 signaling downregulation by trastuzumab and suppression of the PI3K/Akt pathway: an unexpected effect on TRAIL-induced apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polo-like kinases and oncogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
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inferred from DOI database lookup
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase II study of weekly docetaxel and trastuzumab for patients with HER-2-overexpressing metastatic breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antisense therapy for cancer
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
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ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microtubules as a target for anticancer drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The polo-like protein kinases Fnk and Snk associate with a Ca(2+)- and integrin-binding protein and are regulated dynamically with synaptic plasticity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ErbB2 potentiates breast tumor proliferation through modulation of p27(Kip1)-Cdk2 complex formation: receptor overexpression does not determine growth dependency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antibody microinjection reveals an essential role for human polo-like kinase 1 (Plk1) in the functional maturation of mitotic centrosomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Normal cells, but not cancer cells, survive severe Plk1 depletion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhancement of the p27Kip1-mediated antiproliferative effect of trastuzumab (Herceptin) on HER2-overexpressing tumor cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
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Trastuzumab-mediated antibody-dependent cellular cytotoxicity against esophageal squamous cell carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
based on heuristic
inferred from DOI database lookup
HER2 therapy: molecular mechanisms of trastuzumab resistance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
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Herceptin: mechanisms of action and resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
based on heuristic
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P27(kip1) down-regulation is associated with trastuzumab resistance in breast cancer cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
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inferred from DOI database lookup
Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer.
1 reference
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Crossref
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7 January 2021
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Taxol stabilizes microtubules in mouse fibroblast cells
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Crossref
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7 January 2021
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Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
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inferred from DOI database lookup
Malignant transformation of mammalian cells initiated by constitutive expression of the polo-like kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
based on heuristic
inferred from DOI database lookup
Polo-like kinase-1 is a target of the DNA damage checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
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Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
based on heuristic
inferred from DOI database lookup
Down-regulation of Polo-like kinase 1 elevates drug sensitivity of breast cancer cells in vitro and in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer inhibition in nude mice after systemic application of U6 promoter-driven short hairpin RNAs against PLK1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
based on heuristic
inferred from DOI database lookup
RNA interference-based gene silencing in mice: the development of a novel therapeutical strategy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of RNA silencing of polo-like kinase-1 (PLK1) on apoptosis and spindle formation in human cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Downregulation of human polo-like kinase activity by antisense oligonucleotides induces growth inhibition in cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting polo-like kinase 1 for cancer therapy.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
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inferred from DOI database lookup
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1 reference
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Crossref
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7 January 2021
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1 reference
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Crossref
reference URL
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7 January 2021
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inferred from DOI database lookup
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of survivin by ErbB2 signaling: therapeutic implications for ErbB2-overexpressing breast cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
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Stable gene silencing of cyclin B1 in tumor cells increases susceptibility to taxol and leads to growth arrest in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
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7 January 2021
based on heuristic
inferred from DOI database lookup
RNAi-mediated gene silencing in non-human primates.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210355
retrieved
7 January 2021
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Identifiers
DOI
10.1038/SJ.ONC.1210355
1 reference
stated in
Europe PubMed Central
PubMed ID
17369857
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17369857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
Dimensions Publication ID
1043868630
0 references
PubMed ID
17369857
1 reference
stated in
Europe PubMed Central
PubMed ID
17369857
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17369857%20AND%20SRC:MED&resulttype=core&format=json
retrieved
27 December 2019
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