(Q80146770)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15170450%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

review article

1 reference

title

Yeast as a model system for anticancer drug discovery (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15170450%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

Julian A Simon

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15170450%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

Antonio Bedalov

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15170450%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

publication date

1 June 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15170450%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

published in

Nature Reviews Cancer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15170450%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15170450%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

page(s)

481-492

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15170450%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15170450%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrc1372

29 December 2019

exact match

0 references

cites work

Drug target validation and identification of secondary drug target effects using DNA microarrays

1 reference

Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways

31 March 2020

1 reference

A genome-wide screen in Saccharomyces cerevisiae for genes affecting UV radiation sensitivity

31 March 2020

1 reference

Global mapping of the yeast genetic interaction network

31 March 2020

1 reference

Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes

31 March 2020

1 reference

Targets of the cyclin-dependent kinase Cdk1

31 March 2020

1 reference

Comparative assessment of large-scale data sets of protein-protein interactions

31 March 2020

1 reference

Integrating genetic approaches into the discovery of anticancer drugs

31 March 2020

1 reference

The yeast gene ERG6 is required for normal membrane function but is not essential for biosynthesis of the cell-cycle-sparking sterol

31 March 2020

1 reference

Yeast multidrug resistance: the PDR network.

31 March 2020

1 reference

A streamlined process to phenotypically profile heterologous cDNAs in parallel using yeast cell-based assays

31 March 2020

1 reference

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

31 March 2020

1 reference

A Phase II trial of flavopiridol (NSC #649890) in patients with previously untreated metastatic androgen-independent prostate cancer

31 March 2020

1 reference

The p16(INK4A) protein and flavopiridol restore yeast cell growth inhibited by Cdk4

31 March 2020

1 reference

Mechanisms of cytochrome c release by proapoptotic BCL-2 family members

31 March 2020

1 reference

Bax inhibitor-1, a mammalian apoptosis suppressor identified by functional screening in yeast

31 March 2020

1 reference

Linking the epigenetic 'language' of covalent histone modifications to cancer

31 March 2020

1 reference

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

31 March 2020

1 reference

The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability

31 March 2020

1 reference

Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain

31 March 2020

1 reference

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

31 March 2020

1 reference

Negative control of p53 by Sir2alpha promotes cell survival under stress

31 March 2020

1 reference

Acetylation inactivates the transcriptional repressor BCL6.

31 March 2020

1 reference

Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma.

31 March 2020

1 reference

Assays for gene silencing in yeast

31 March 2020

1 reference

Identification of a small molecule inhibitor of Sir2p

31 March 2020

1 reference

NAD+-dependent deacetylase Hst1p controls biosynthesis and cellular NAD+ levels in Saccharomyces cerevisiae

31 March 2020

1 reference

Identification of Selective Inhibitors of NAD+-dependent Deacetylases Using Phenotypic Screens in Yeast

31 March 2020

1 reference

Inhibitors of Sir2: evaluation of splitomicin analogues

31 March 2020

1 reference

Deficient DNA mismatch repair: a common etiologic factor for colon cancer

31 March 2020

1 reference

The retinoblastoma protein and cell cycle control

31 March 2020

1 reference

Use of isogenic human cancer cells for high-throughput screening and drug discovery

31 March 2020

1 reference

Cell-based assays for identification of novel double-strand break-inducing agents

31 March 2020

1 reference

Mutations of mitotic checkpoint genes in human cancers

31 March 2020

1 reference

Mitotic checkpoints: from yeast to cancer

31 March 2020

1 reference

S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function

31 March 2020

1 reference

Yeast three-hybrid system for detecting ligand-receptor interactions

31 March 2020

1 reference

Functional discovery via a compendium of expression profiles

31 March 2020

1 reference

Proteomics-based target identification: bengamides as a new class of methionine aminopeptidase inhibitors

31 March 2020

1 reference

31 March 2020

1 reference

Histone Deacetylases: Unique Players in Shaping the Epigenetic Histone Code

31 March 2020

1 reference

"SIRT8" expressed in thyroid cancer is actually SIRT7.

31 March 2020

1 reference

Acute myeloid leukemia with inv(8)(p11q13).

31 March 2020

1 reference

MLL5, a homolog of Drosophila trithorax located within a segment of chromosome band 7q22 implicated in myeloid leukemia

31 March 2020

1 reference

The polycomb group protein EZH2 is involved in progression of prostate cancer

31 March 2020

1 reference

In multiple myeloma, t(4;14)(p16;q32) is an adverse prognostic factor irrespective of FGFR3 expression

31 March 2020

1 reference

Dot1p modulates silencing in yeast by methylation of the nucleosome core

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRC1372

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15170450%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 December 2019

0 references

1 reference