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English
Cooperation between CD4 and CD8 T cells for anti-tumor activity is enhanced by OX40 signals
scientific article published on 01 May 2007
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17429847
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17429847%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
title
Cooperation between CD4 and CD8 T cells for anti-tumor activity is enhanced by OX40 signals
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17429847
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17429847%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
main subject
cooperation
1 reference
based on heuristic
inferred from title
author name string
Aihua Song
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17429847
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17429847%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
Jianxun Song
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17429847
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17429847%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
Xiaohong Tang
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17429847
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17429847%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
Michael Croft
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17429847
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17429847%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
publication date
1 May 2007
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17429847
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17429847%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
published in
European Journal of Immunology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17429847
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17429847%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
volume
37
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17429847
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17429847%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
issue
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17429847
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17429847%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
page(s)
1224-1232
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17429847
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17429847%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
cites work
The OX40 costimulatory receptor determines the development of CD4 memory by regulating primary clonal expansion.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sustained survivin expression from OX40 costimulatory signals drives T cell clonal expansion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Signaling through OX40 (CD134) breaks peripheral T-cell tolerance.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Presence of the T-cell activation marker OX-40 on tumor infiltrating lymphocytes and draining lymph node cells from patients with melanoma and head and neck cancers
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immunohistochemical analysis of primary breast tumors and tumor-draining lymph nodes by means of the T-cell costimulatory molecule OX-40.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Survival in human colorectal cancer correlates with expression of the T-cell costimulatory molecule OX-40 (CD134).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Engagement of the OX-40 receptor in vivo enhances antitumor immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Augmentation versus inhibition: effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
OX40 ligation enhances primary and memory cytotoxic T lymphocyte responses in an immunotherapy for hepatic colon metastases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Costimulation of CD8 T cell responses by OX40.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Vaccination with dendritic cells pulsed with apoptotic tumors in combination with anti-OX40 and anti-4-1BB monoclonal antibodies induces T cell-mediated protective immunity in Her-2/neu transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Adenovirus vector-mediated in vivo gene transfer of OX40 ligand to tumor cells enhances antitumor immunity of tumor-bearing hosts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhancing the immunostimulatory function of dendritic cells by transfection with mRNA encoding OX40 ligand.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional dichotomy between OX40 and 4-1BB in modulating effector CD8 T cell responses.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer immunotherapy: moving beyond current vaccines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumor lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of adoptively transferred CD8 T cells and host cells in the control of the growth of the EG7 thymoma: factors that determine the relative effectiveness and homing properties of Tc1 and Tc2 effectors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of tumor rejection by γδ T cells and IL-10
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spontaneous elicitation of potent antitumor immunity and eradication of established tumors by administration of DNA encoding soluble transforming growth factor-beta II receptor without active antigen-sensitization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CTLA-4 blockade reverses CD8+ T cell tolerance to tumor by a CD4+ T cell- and IL-2-dependent mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
OX40 and Bcl-xL promote the persistence of CD8 T cells to recall tumor-associated antigen.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Opposing effects of IL-2 in tumor immunotherapy: promoting CD8 T cell growth and inducing apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transition of late-stage effector T cells to CD27+ CD28+ tumor-reactive effector memory T cells in humans after adoptive cell transfer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bedside to bench and back again: how animal models are guiding the development of new immunotherapies for cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Type 1 and type 2 CD8+ effector T cell subpopulations promote long-term tumor immunity and protection to progressively growing tumor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of cytotoxic T-cell responses in vivo in the absence of CD4 helper cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epitope affinity for MHC class I determines helper requirement for CTL priming.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor-specific CD4+ T lymphocytes from cancer patients are required for optimal induction of cytotoxic T cells against the autologous tumor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor-specific CD4+ T cells have a major "post-licensing" role in CTL mediated anti-tumor immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD4+ T cell help impairs CD8+ T cell deletion induced by cross-presentation of self-antigens and favors autoimmunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD40 antibody evokes a cytotoxic T-cell response that eradicates lymphoma and bypasses T-cell help
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: a critical role for CD70 in CD8 T cell priming by CD40-licensed APCs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of CD70 on dendritic cells through CD40 or TLR stimulation contributes to the development of CD8+ T cell responses in the absence of CD4+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reversal of CD8+ T cell ignorance and induction of anti-tumor immunity by peptide-pulsed APC
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FEJI.200636957
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1002/EJI.200636957
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17429847
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17429847%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
PubMed publication ID
17429847
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17429847
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17429847%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
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