(Q80282025)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17486080%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma (English)

1 reference

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30 December 2019

1 reference

2

1 reference

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30 December 2019

Chris Pugh

7

1 reference

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30 December 2019

author name string

J S P Yuen

1

1 reference

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30 December 2019

M Sullivan

3

1 reference

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30 December 2019

A Protheroe

4

1 reference

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30 December 2019

G D H Turner

5

1 reference

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30 December 2019

I S Roberts

6

1 reference

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30 December 2019

H Werner

8

1 reference

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30 December 2019

V M Macaulay

9

1 reference

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30 December 2019

publication date

7 May 2007

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30 December 2019

1 reference

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30 December 2019

volume

26

1 reference

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30 December 2019

issue

45

1 reference

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30 December 2019

page(s)

6499-6508

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1210474

30 December 2019

exact match

0 references

cites work

BRCA1–Sp1 interactions in transcriptional regulation of the IGF‐IR gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

The expression of insulin-like growth factor-I receptor correlates with Fuhrman grading of renal cell carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Genetic and epigenetic analysis of von Hippel-Lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

The efficacy of small interfering RNAs targeted to the type 1 insulin-like growth factor receptor (IGF1R) is influenced by secondary structure in the IGF1R transcript

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Highly selective actions of HuR in antagonizing AU-rich element-mediated mRNA destabilization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

An important von Hippel-Lindau tumor suppressor domain mediates Sp1-binding and self-association

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

The von Hippel-Lindau tumor suppressor complex and regulation of hypoxia-inducible transcription

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Analysis of the human type I insulin-like growth factor receptor promoter region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motif

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Role of elongin-binding domain of von Hippel Lindau gene product on HuR-mediated VPF/VEGF mRNA stability in renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Inhibition of insulin-like growth factor-I-mediated cell signaling by the von Hippel-Lindau gene product in renal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

A KH domain RNA binding protein, KSRP, promotes ARE-directed mRNA turnover by recruiting the degradation machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Mutations of the VHL tumour suppressor gene in renal carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Expression of insulin-like growth factor-1 receptor in human colorectal cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Hypoxia--a key regulatory factor in tumour growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Gene expression signatures for colorectal cancer microsatellite status and HNPCC.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Cloning and Characterization of the Human Insulin-Like Growth Factor-I Receptor Gene 5′-Flanking Region

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

The ELAV RNA-stability factor HuR binds the 5'-untranslated region of the human IGF-IR transcript and differentially represses cap-dependent and IRES-mediated translation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Comparison of hypoxia transcriptome in vitro with in vivo gene expression in human bladder cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Expression of insulin-like growth factor I receptor and survival in patients with clear cell renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Pathologic T1 clear cell renal cell carcinoma: insulin-like growth factor-I receptor expression and disease-specific survival.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

A new mathematical model for relative quantification in real-time RT-PCR

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

von Hippel-Lindau tumor suppressor protein represses platelet-derived growth factor B-chain gene expression via the Sp1 binding element in the proximal PDGF-B promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

The EGF receptor interacts with the type 1 IGF receptor and regulates its stability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Silencing of the IGF1R gene enhances sensitivity to DNA-damaging agents in both PTEN wild-type and mutant human prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Hypoxia increases insulinlike growth factor gene expression in rat osteoblasts.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Regulation of hypoxia-inducible factor (HIF)-1 activity and expression of HIF hydroxylases in response to insulin-like growth factor I.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

New concepts in regulation and function of the insulin-like growth factors: implications for understanding normal growth and neoplasia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1210474

7 January 2021