(Q80396496)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17534577%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

In vitro chemosensitivity of freshly explanted tumor cells to pemetrexed is correlated with target gene expression (English)

1 reference

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31 December 2019

author name string

Axel-Rainer Hanauske

1

1 reference

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31 December 2019

Ulrike Eismann

2

1 reference

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31 December 2019

Olaf Oberschmidt

3

1 reference

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31 December 2019

Heike Pospisil

4

1 reference

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31 December 2019

Steve Hoffmann

5

1 reference

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31 December 2019

Hartmut Hanauske-Abel

6

1 reference

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31 December 2019

Doreen Ma

7

1 reference

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31 December 2019

Victor Chen

8

1 reference

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31 December 2019

Paolo Paoletti

9

1 reference

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31 December 2019

Clet Niyikiza

10

1 reference

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31 December 2019

publication date

30 May 2007

1 reference

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Investigational New Drugs

31 December 2019

published in

1 reference

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31 December 2019

volume

25

1 reference

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31 December 2019

issue

5

1 reference

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31 December 2019

page(s)

417-423

1 reference

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https://scigraph.springernature.com/pub.10.1007/s10637-007-9060-9

31 December 2019

exact match

0 references

cites work

A phase II trial of pemetrexed in advanced breast cancer: clinical response and association with molecular target expression

1 reference

12 December 2020

Cytotoxic effects of pemetrexed in gastric cancer cells

1 reference

12 December 2020

Thymidilate synthase and p53 primary tumour expression as predictive factors for advanced colorectal cancer patients

1 reference

12 December 2020

Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase.

1 reference

12 December 2020

Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5

1 reference

12 December 2020

Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression

1 reference

12 December 2020

Thymidylate synthase mRNA level in adenocarcinoma of the stomach: a predictor for primary tumor response and overall survival

1 reference

12 December 2020

Decreased expression of the reduced folate carrier and folypolyglutamate synthetase is the basis for acquired resistance to the pemetrexed antifolate (LY231514) in an L1210 murine leukemia cell line

1 reference

12 December 2020

Increased thymidylate synthase gene expression in liver metastases from colorectal carcinoma: implications for chemotherapeutic options and survival

1 reference

12 December 2020

Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity

1 reference

12 December 2020

Pemetrexed safety and dosing strategy

1 reference

12 December 2020

Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy

1 reference

12 December 2020

Preclinical activity of taxotere (RP 56976, NSC 628503) against freshly explanted clonogenic human tumour cells: comparison with taxol and conventional antineoplastic agents.

1 reference

12 December 2020

Cellular and pharmacogenetics foundation of synergistic interaction of pemetrexed and gemcitabine in human non-small-cell lung cancer cells

1 reference

12 December 2020

Biological activity of the multitargeted antifolate, MTA (LY231514), in human cell lines with different resistance mechanisms to antifolate drugs

1 reference

12 December 2020

Thymidylate synthase protein expression in advanced colon cancer: correlation with the site of metastasis and the clinical response to leucovorin-modulated bolus 5-fluorouracil

1 reference

12 December 2020

Multiple folate enzyme inhibition: mechanism of a novel pyrrolopyrimidine-based antifolate LY231514 (MTA).

1 reference

12 December 2020

Kinetic validation of the use of carboxydichlorofluorescein as a drug surrogate for MRP5-mediated transport

1 reference

12 December 2020

Substrate specificity of mammalian folylpolyglutamate synthetase for 5,10-dideazatetrahydrofolate analogs

1 reference

12 December 2020

The role of Alimta in the treatment of malignant pleural mesothelioma: an overview of preclinical and clinical trials

1 reference

12 December 2020

Role of MRP4 and MRP5 in biology and chemotherapy

1 reference

12 December 2020

Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors

1 reference

12 December 2020

Overview of phase I/II pemetrexed studies

1 reference

12 December 2020

The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites

1 reference

12 December 2020

Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma

1 reference

12 December 2020