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Cyclin-dependent kinases as targets for cancer therapy
scientific article published on 01 January 2003
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Europe PubMed Central
PubMed publication ID
15338744
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15338744%20AND%20SRC:MED&resulttype=core&format=json
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1 January 2020
review article
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Europe PubMed Central
title
Cyclin-dependent kinases as targets for cancer therapy
(English)
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stated in
Europe PubMed Central
PubMed publication ID
15338744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15338744%20AND%20SRC:MED&resulttype=core&format=json
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1 January 2020
author name string
Manish A Shah
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
15338744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15338744%20AND%20SRC:MED&resulttype=core&format=json
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1 January 2020
Gary K Schwartz
series ordinal
2
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Europe PubMed Central
PubMed publication ID
15338744
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1 January 2020
publication date
1 January 2003
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Europe PubMed Central
PubMed publication ID
15338744
reference URL
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1 January 2020
published in
Cancer chemotherapy and biological response modifiers
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Europe PubMed Central
PubMed publication ID
15338744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15338744%20AND%20SRC:MED&resulttype=core&format=json
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1 January 2020
volume
21
1 reference
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Europe PubMed Central
PubMed publication ID
15338744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15338744%20AND%20SRC:MED&resulttype=core&format=json
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1 January 2020
page(s)
145-170
1 reference
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Europe PubMed Central
PubMed publication ID
15338744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15338744%20AND%20SRC:MED&resulttype=core&format=json
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1 January 2020
cites work
CDK inhibitors: positive and negative regulators of G1-phase progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclins and cell cycle checkpoints
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human and yeast cdk-activating kinases (CAKs) display distinct substrate specificities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A Restriction Point for Control of Normal Animal Cell Proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
To cycle or not to cycle: a critical decision in cancer.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The S phase: Beginning, middle, and end: A perspective.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The DNA damage response: putting checkpoints in perspective
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer and the cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spindle assembly and the art of regulating microtubule dynamics by MAPs and Stathmin/Op18.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The spindle assembly checkpoint
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How cells get the right chromosomes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BIRinging chromosomes through cell division--and survivin' the experience
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The molecular basis and potential role of survivin in cancer diagnosis and therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A p34(cdc2) survival checkpoint in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle control and cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cdk inhibitors in development and cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An antiinflammatory cum immunomodulatory piperidinylbenzopyranone from dysoxylum binectariferum : isolation, structure and total synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase I clinical and pharmacokinetic trial of the cyclin-dependent kinase inhibitor flavopiridol
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase I trial of continuous infusion flavopiridol, a novel cyclin-dependent kinase inhibitor, in patients with refractory neoplasms.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Flavopiridol, a novel cyclin-dependent kinase inhibitor, in metastatic renal cancer: a University of Chicago Phase II Consortium study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase II study of the cyclin-dependent kinase inhibitor flavopiridol administered to patients with advanced gastric carcinoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Seventy-two hour continuous infusion flavopiridol in relapsed and refractory mantle cell lymphoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase I clinical and pharmacokinetic study of flavopiridol administered as a daily 1-hour infusion in patients with advanced neoplasms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
UCN-01 and UCN-02, new selective inhibitors of protein kinase C. II. Purification, physico-chemical properties, structural determination and biological activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calphostin C (UCN-1028C), a novel microbial compound, is a highly potent and specific inhibitor of protein kinase C
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of UCN-01, a selective inhibitor of protein kinase C, on the cell-cycle distribution of human epidermoid carcinoma, A431 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
UCN-01, 7-hydroxyl-staurosporine, inhibits kinase activity of cyclin-dependent kinases and reduces the phosphorylation of the retinoblastoma susceptibility gene product in A549 human lung cancer cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The retinoblastoma gene product is a negative modulator of the apoptotic pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in SENCAR mouse skin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A phase I study of intravenous bryostatin 1 in patients with advanced cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase I study of bryostatin 1: assessment of interleukin 6 and tumor necrosis factor alpha induction in vivo. The Cancer Research Campaign Phase I Committee
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A phase II trial of bryostatin 1 in patients with non-Hodgkin's lymphoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A model for tumor response to chemotherapy: an integration of the stem cell and somatic mutation hypotheses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accumulation of p53 protein as a possible predictor of response to adjuvant combination chemotherapy with cyclophosphamide, methotrexate, fluorouracil, and prednisone for breast cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell death: the significance of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dysregulation of apoptosis in cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An evolutionary perspective on apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of apoptosis: integration of genetic, biochemical, and cellular indicators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis and cancer drug targeting
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis in cancer therapy: crossing the threshold
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis. Its significance in cancer and cancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell death in health and disease: the biology and regulation of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Implications of apoptotic cell death regulation in cancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Survival factors, intracellular signal transduction, and the activation of endonucleases in apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis meets signal transduction: elimination of a BAD influence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase C targeting in antineoplastic treatment strategies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53, the cellular gatekeeper for growth and division
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Radiation-induced cell cycle arrest compromised by p21 deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of p53 in human cancer cells alters the responses to therapeutic agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification and classification of p53-regulated genes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-cycle arrest versus cell death in cancer therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
THE DEVELOPMENT AND CLINICAL UTILITY OF THE TAXANE CLASS OF ANTIMICROTUBULE CHEMOTHERAPY AGENTS
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Promotion of microtubule assembly in vitro by taxol
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Taxol assembles tubulin in the absence of exogenous guanosine 5'-triphosphate or microtubule-associated proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Taxol stabilizes microtubules in mouse fibroblast cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A phase I trial of taxol given by a 6-hour intravenous infusion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Accumulation of cyclin B1, activation of cyclin B1-dependent kinase and induction of programmed cell death in human epidermoid carcinoma KB cells treated with taxol.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Temporal and spatial control of cyclin B1 destruction in metaphase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytotoxicity of the anticancer agents cisplatin and taxol during cell proliferation and the cell cycle.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of Bcl-2 protein and association with p21Ras in Ras-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular effects of paclitaxel: myths and reality (a critical review).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential Taxol-dependent arrest of transformed and nontransformed cells in the G1 phase of the cell cycle, and specific-related mortality of transformed cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Paclitaxel-induced cell death: where the cell cycle and apoptosis come together
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of the bcl-2 phosphorylation loop domain increases resistance of human leukemia cells (U937) to paclitaxel-mediated mitochondrial dysfunction and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-xL modulates apoptosis induced by anticancer drugs and delays DEVDase and DNA fragmentation-promoting activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bryostatin 1 enhances paclitaxel-induced mitochondrial dysfunction and apoptosis in human leukemia cells (U937) ectopically expressing Bcl-xL
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of bryostatin 1 on taxol-induced apoptosis and cytotoxicity in human leukemia cells (U937).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The current status of camptothecin analogues as antitumor agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Topoisomerase I inhibitors: topotecan and irenotecan
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abrogation of the S phase DNA damage checkpoint results in S phase progression or premature mitosis depending on the concentration of 7-hydroxystaurosporine and the kinetics of Cdc25C activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Topoisomerase-I inhibitors for human malignant glioma: differential modulation of p53, p21, bax and bcl-2 expression and of CD95-mediated apoptosis by camptothecin and beta-lapachone.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase I clinical and pharmacokinetic study of irinotecan, fluorouracil, and leucovorin in patients with advanced solid tumors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Clinical trials of irinotecan hydrochloride (CPT, campto injection, topotecin injection) in Japan
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhancement of camptothecin-induced cytotoxicity with UCN-01 in breast cancer cells: abrogation of S/G(2) arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptotic response to camptothecin and 7-hydroxystaurosporine (UCN-01) in the 8 human breast cancer cell lines of the NCI Anticancer Drug Screen: multifactorial relationships with topoisomerase I, protein kinase C, Bcl-2, p53, MDM-2 and caspase path
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kinetics and thermodynamics of the interaction of 5-fluoro-2'-deoxyuridylate with thymidylate synthase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequence-dependent antagonism between fluorouracil and paclitaxel in human breast cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effect of 5-fluorouracil on cell cycle regulatory proteins in human colon cancer cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell-cycle-directed regulation of thymidylate synthase messenger RNA in human diploid fibroblasts stimulated to proliferate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA damage and cell cycle checkpoints
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of apoptosis by taxol and cisplatin and effect on cell cycle-related proteins in cisplatin-sensitive and -resistant human ovarian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
UCN-01 enhances the in vitro toxicity of clinical agents in human tumor cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
UCN-01 selectively enhances mitomycin C cytotoxicity in p53 defective cells which is mediated through S and/or G(2) checkpoint abrogation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle effects of gemcitabine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of p53 in gemcitabine-mediated cytotoxicity and radiosensitization.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of a non-functional p53 affects the sensitivity of cancer cells to gemcitabine.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of transfected human ribonucleotide reductase M2 subunit in human cancer cells enhances their invasive potential
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle perturbations in acute myeloid leukemia samples following in vitro exposures to therapeutic agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0921-4410%2803%2921007-3
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0921-4410(03)21007-3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15338744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15338744%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
PubMed publication ID
15338744
1 reference
stated in
Europe PubMed Central
PubMed publication ID
15338744
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15338744%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 January 2020
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