(Q81244699)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15639301%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Treating individuals 2. Subgroup analysis in randomised controlled trials: importance, indications, and interpretation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15639301%20AND%20SRC:MED&resulttype=core&format=json

randomized controlled trial

7 January 2020

main subject

1 reference

Peter M Rothwell

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15639301%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

language of work or name

English

0 references

publication date

1 January 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15639301%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15639301%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

365

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15639301%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

9454

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15639301%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

176-186

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15639301%20AND%20SRC:MED&resulttype=core&format=json

The problem of cogent subgroups: a clinicostatistical tragedy

7 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Why do we need some large, simple randomized trials?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Reliable assessment of the effects of treatment on mortality and major morbidity, I: clinical trials

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Generalizing the results of randomized clinical trials

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Meta-analysis. Beyond the grand mean?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Problems in the medical interpretation of overviews

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Summing up evidence: one answer is not always enough.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Uncontrolled pearls, controlled evidence, meta-analysis and the individual patient.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Evidence in consultations: interpreted and individualised

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Prognosis of symptoms that are medically unexplained. Follow up study needs to be continued for longer

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

A consumer's guide to subgroup analyses

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Size isn't everything

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Evidence based medicine: concerns of a clinical neurologist

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Evidence-based and evidence-biased medicine

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Evidence-based medicine and hypertension.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Problems in the "evidence" of "evidence-based medicine"

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Can randomised trials inform clinical decisions about individual patients?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Finding and applying evidence during clinical rounds: the "evidence cart".

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Applying overviews and meta-analyses at the bedside

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Inpatient general medicine is evidence based

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

External validity of randomised controlled trials: "to whom do the results of this trial apply?".

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Can overall results of clinical trials be applied to all patients?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

The revised CONSORT statement for reporting randomized trials: explanation and elaboration

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

A Randomized Trial of Aspirin and Sulfinpyrazone in Threatened Stroke

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Controlled trial of aspirin in cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Collaborative overview of randomised trials of antiplatelet therapy--I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Antiplatelet Trialists' Collaboration

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Hypertension in women: what is really known? The Women's Caucus, Working Group on Women's Health of the Society of General Internal Medicine

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

MRC trial of treatment of mild hypertension: principal results. Medical Research Council Working Party

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Effect of antihypertensive drug treatment on cardiovascular outcomes in women and men. A meta-analysis of individual patient data from randomized, controlled trials. The INDANA Investigators

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Antihypertensive drugs in very old people: a subgroup meta-analysis of randomised controlled trials. INDANA Group

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Is aspirin safe for patients with heart failure?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Long-term ACE-inhibitor therapy in patients with heart failure or left-ventricular dysfunction: a systematic overview of data from individual patients. ACE-Inhibitor Myocardial Infarction Collaborative Group

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Effect of alprenolol on mortality among patients with definite or suspected acute myocardial infarction. Preliminary results

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Beta blockade during and after myocardial infarction: an overview of the randomized trials

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Reduction in mortality after myocardial infarction with long-term beta-adrenoceptor blockade. Multicentre international study: supplementary report

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Effects of adjuvant tamoxifen and of cytotoxic therapy on mortality in early breast cancer. An overview of 61 randomized trials among 28,896 women.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Benefit of carotid endarterectomy in patients with symptomatic moderate or severe stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Low-dose and high-dose acetylsalicylic acid for patients undergoing carotid endarterectomy: a randomised controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Effect of amlodipine on morbidity and mortality in severe chronic heart failure. Prospective Randomized Amlodipine Survival Evaluation Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Neurohormones and oxidative stress in nonischemic cardiomyopathy: relationship to survival and the effect of treatment with amlodipine

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Analysis and interpretation of treatment effects in subgroups of patients in randomized clinical trials

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

High-risk and population strategies of prevention: ethical considerations

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Subgroup analysis and other (mis)uses of baseline data in clinical trials

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

The use and abuse of subgroup analysis in epidemiological research

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Estimation issues in clinical trials and overviews

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Subgroup analyses in randomised controlled trials: quantifying the risks of false-positives and false-negatives

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Reporting on methods of subgroup analysis in clinical trials: a survey of four scientific journals

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Guidelines for carotid endarterectomy: a statement for healthcare professionals from a special writing group of the Stroke Council, American Heart Association

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke: 2002 Update: Consensus Panel Guide to Comprehensive Risk Reduction for Adult Patients Without Coronary or Other Atherosclerotic Vascular Diseases. American Heart Association

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

A systematic comparison of the risks of stroke and death due to carotid endarterectomy for symptomatic and asymptomatic stenosis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Systematic review of the risks of carotid endarterectomy in relation to the clinical indication for and timing of surgery

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Prediction of benefit from carotid endarterectomy in individual patients: a risk-modelling study. European Carotid Surgery Trialists' Collaborative Group

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Endarterectomy for symptomatic carotid stenosis in relation to clinical subgroups and timing of surgery

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

The impact of high-risk patients on the results of clinical trials

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Effect of coronary artery bypass graft surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

An effect model for the assessment of drug benefit: example of antiarrhythmic drugs in postmyocardial infarction patients

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Aspirin for primary prevention of coronary heart disease: safety and absolute benefit related to coronary risk derived from meta-analysis of randomised trials

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Benefit of clopidogrel in patients with acute coronary syndromes without ST-segment elevation in various risk groups

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

The TIMI Risk Score for Unstable Angina/Non–ST Elevation MI

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease. Efficacy and Safety of Subcutaneous Enoxaparin in Non-Q-Wave Coronary Events Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Prevention of first bleeding in cirrhosis. A meta-analysis of randomized trials of nonsurgical treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Unruptured intracranial aneurysms--risk of rupture and risks of surgical intervention

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Limitations of clinical diagnosis in acute stroke

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

National clinical guidelines for stroke: a concise update

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Cerebral metabolism of patients with stenosis or occlusion of the internal carotid artery. A 1H-MR spectroscopic imaging study

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Importance of hemodynamic factors in the prognosis of symptomatic carotid occlusion

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Relationship between blood pressure and stroke risk in patients with symptomatic carotid occlusive disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

The effect of antilymphocyte induction therapy on renal allograft survival. A meta-analysis of individual patient-level data. Anti-Lymphocyte Antibody Induction Therapy Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Treatment of Chlamydia pneumoniae infection with roxithromycin and effect on neointima proliferation after coronary stent placement (ISAR-3): a randomised, double-blind, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Some statistical data on atypical cholinesterase of human serum

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Genetic control of isoniazid metabolism in man

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Inheritance and drug response

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Potential role of pharmacogenomics in reducing adverse drug reactions: a systematic review

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: a molecular study

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Individualising HIV treatment--pharmacogenetics and immunogenetics

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Effect of pravastatin on coronary disease events in subgroups defined by coronary risk factors: the Prospective Pravastatin Pooling Project

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Quantitative analysis of the admission electrocardiogram identifies patients with unstable coronary artery disease who benefit the most from early invasive treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Concorde trial of immediate versus deferred zidovudine

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Population based study of early risk of stroke after transient ischaemic attack or minor stroke: implications for public education and organisation of services

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Early risk of recurrence by subtype of ischemic stroke in population-based incidence studies

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Systematic review of evidence on thrombolytic therapy for acute ischaemic stroke

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Matching the right drug to the right patient in essential hypertension

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

The effect of diltiazem on mortality and reinfarction after myocardial infarction

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

A randomized trial of propranolol in patients with acute myocardial infarction. I. Mortality results

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Statistical problems in the reporting of clinical trials. A survey of three medical journals.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

False-positive results in clinical trials: multiple significance tests and the problem of unreported comparisons.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Interpretation of results from subset analyses within overviews of randomized clinical trials

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Assessing the potential for bias in meta-analysis due to selective reporting of subgroup analyses within studies

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

Randomised trial of home-based psychosocial nursing intervention for patients recovering from myocardial infarction.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2805%2917709-5

7 January 2021

10.1016/S0140-6736(05)17709-5

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15639301%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference