(Q81274554)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18479220%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

review article

1 reference

title

New uses for old copper-binding drugs: converting the pro-angiogenic copper to a specific cancer cell death inducer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18479220%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

0 references

1 reference

Di Chen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18479220%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Q Ping Dou

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18479220%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

publication date

1 June 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18479220%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

7 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18479220%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18479220%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18479220%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

739-748

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18479220%20AND%20SRC:MED&resulttype=core&format=json

The ubiquitin-proteasome system

7 January 2020

cites work

1 reference

12 December 2020

The copper-chelating agent, trientine, suppresses tumor development and angiogenesis in the murine hepatocellular carcinoma cells.

1 reference

12 December 2020

Conservation of a stress response: human heat shock transcription factors functionally substitute for yeast HSF.

1 reference

12 December 2020

Ubiquitin-mediated proteolysis: biological regulation via destruction

1 reference

12 December 2020

Cellular copper transport and metabolism

1 reference

12 December 2020

Bortezomib inhibits nuclear factor-kappaB dependent survival and has potent in vivo activity in mesothelioma.

1 reference

12 December 2020

Anti-cancer effects of bortezomib against chemoresistant neuroblastoma cell lines in vitro and in vivo.

1 reference

12 December 2020

Pyrrolidine dithiocarbamate-zinc(II) and -copper(II) complexes induce apoptosis in tumor cells by inhibiting the proteasomal activity

1 reference

12 December 2020

Serum and tissue trace elements in patients with breast cancer in Taiwan

1 reference

12 December 2020

Clioquinol and pyrrolidine dithiocarbamate complex with copper to form proteasome inhibitors and apoptosis inducers in human breast cancer cells

1 reference

12 December 2020

Abnormally high expression of proteasomes in human leukemic cells

1 reference

12 December 2020

Copper and ceruloplasmin status in serum of prostate and colon cancer patients

1 reference

12 December 2020

Clioquinol, a drug for Alzheimer's disease specifically interfering with brain metal metabolism: structural characterization of its zinc(II) and copper(II) complexes

1 reference

12 December 2020

Treatment of Alzheimer's disease with clioquinol

1 reference

12 December 2020

The copper chelator trientine has an antiangiogenic effect against hepatocellular carcinoma, possibly through inhibition of interleukin-8 production

1 reference

12 December 2020

Preclinical and clinical evaluation of proteasome inhibitor PS-341 for the treatment of cancer

1 reference

12 December 2020

Vascular endothelial growth factor and vascular endothelial growth factor receptor inhibitors as anti-angiogenic agents in cancer therapy

1 reference

12 December 2020

Bortezomib therapy alone and in combination with dexamethasone for previously untreated symptomatic multiple myeloma

1 reference

12 December 2020

The molecular biology of metal ion transport in Saccharomyces cerevisiae

1 reference

12 December 2020

Plasma copper and zinc levels in patients with malignant tumors of digestive organs: clinical evaluation of the C1/Zn ratio

1 reference

12 December 2020

Rat epigastric flap survival and VEGF expression after local copper application

1 reference

12 December 2020

PROPHYLAXIS AND THERAPY OF AMEBIASIS AND SHIGELLOSIS WITH IODOCHLORHYDROXYQUIN.

1 reference

12 December 2020

Metal-protein attenuating compounds and Alzheimer's disease

1 reference

12 December 2020

Serum and tissue trace metal levels in lung cancer

1 reference

12 December 2020

The role of copper in tumour angiogenesis

1 reference

12 December 2020

Phase II trial of tetrathiomolybdate in patients with advanced kidney cancer

1 reference

12 December 2020

Structure and mechanism of copper, zinc superoxide dismutase

1 reference

12 December 2020

Prophylactic value of clioquinol against travellers' diarrhoea.

1 reference

12 December 2020

Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts

1 reference

12 December 2020

Bortezomib (millennium pharmaceuticals).

1 reference

12 December 2020

Tumor angiogenesis: therapeutic implications

1 reference

12 December 2020

Comparison between concentrations of trace elements in normal and neoplastic human breast tissue

1 reference

12 December 2020

Serum ceruloplasmin and copper levels in patients with primary brain tumors

1 reference

12 December 2020

Clioquinol, a therapeutic agent for Alzheimer's disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, and antitumor activities in human prostate cancer cells and xenografts

1 reference

12 December 2020

Anti-angiogenesis: new concept for therapy of solid tumors

1 reference

12 December 2020

Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts

1 reference

12 December 2020

Subacute myelo-optic neuropathy and clioquinol. An epidemiological case-history for diagnosis

1 reference

12 December 2020

A review of the pharmacokinetics and pharmacodynamics of disulfiram and its metabolites

1 reference

12 December 2020

Functions of the proteasome: the lysis at the end of the tunnel

1 reference

12 December 2020

First proteasome inhibitor approved for multiple myeloma

1 reference

12 December 2020

Copper-induced vascular endothelial growth factor expression and wound healing

1 reference

12 December 2020

The price of innovation: new estimates of drug development costs

1 reference

12 December 2020

A randomized, controlled dose response study of intravenous sodium diethyldithiocarbamate in patients with advanced human immunodeficiency virus infection

1 reference

12 December 2020

p53-dependent induction of apoptosis by proteasome inhibitors

1 reference

12 December 2020

Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies

1 reference

12 December 2020

A gated channel into the proteasome core particle

1 reference

12 December 2020

The proteasome inhibitor PS-341 in cancer therapy.

1 reference

12 December 2020

Interruption of tumor cell cycle progression through proteasome inhibition: implications for cancer therapy.

1 reference

12 December 2020

Treatment of metastatic cancer with tetrathiomolybdate, an anticopper, antiangiogenic agent: Phase I study.

1 reference

12 December 2020

Disulfiram facilitates intracellular Cu uptake and induces apoptosis in human melanoma cells.

1 reference

12 December 2020

Association between oxidative stress and changes of trace elements in patients with breast cancer

1 reference

12 December 2020

Human aldehyde dehydrogenase: mechanism of inhibition of disulfiram

1 reference

12 December 2020

Role of copper in tumour angiogenesis--clinical implications

1 reference

12 December 2020

Inhibition of HIV progression by dithiocarb. German DTC Study Group

1 reference

12 December 2020

Regulation of transition metal transport across the yeast plasma membrane

1 reference

12 December 2020

Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

1 reference

12 December 2020

Copper stimulates proliferation of human endothelial cells under culture

1 reference

12 December 2020

Tetrathiomolybdate anticopper therapy for Wilson's disease inhibits angiogenesis, fibrosis and inflammation.

1 reference

12 December 2020

Copper control as an antiangiogenic anticancer therapy: lessons from treating Wilson's disease

1 reference

12 December 2020

Changes in uptake of vitamin B(12) and trace metals in brains of mice treated with clioquinol

1 reference

12 December 2020

New uses for old drugs

1 reference

12 December 2020

The zinc and copper content of blood leucocytes and plasma from patients with benign and malignant prostates

1 reference

12 December 2020

A phase 2 study of bortezomib in relapsed, refractory myeloma

1 reference

12 December 2020

Pyrrolidine dithiocarbamate reduces coxsackievirus B3 replication through inhibition of the ubiquitin-proteasome pathway

1 reference

12 December 2020

Adaptation to high and low copper intakes: its relevance to estimated safe and adequate daily dietary intakes

1 reference

12 December 2020

Catalytic activities of the 20 S proteasome, a multicatalytic proteinase complex

1 reference

12 December 2020

Isolation of a cDNA encoding the human homolog of COX17, a yeast gene essential for mitochondrial copper recruitment

1 reference

12 December 2020

Copper transport and Alzheimer's disease

1 reference

12 December 2020

Prevention of cancer cachexia by pyrrolidine dithiocarbamate (PDTC) in colon 26 tumor-bearing mice

1 reference

12 December 2020

Angiogenesis inhibitors. New agents in cancer therapy

1 reference

12 December 2020

Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse model

1 reference

12 December 2020

Pipes and wiring: the regulation of copper uptake and distribution in yeast.

1 reference

12 December 2020

Disulfiram, a clinically used anti-alcoholism drug and copper-binding agent, induces apoptotic cell death in breast cancer cultures and xenografts via inhibition of the proteasome activity

1 reference

12 December 2020

Endothelial cell phagokinesis in response to specific metal ions

1 reference

12 December 2020

The substrate translocation channel of the proteasome

1 reference

12 December 2020

Tumour vasculature as a target for anticancer therapy.

1 reference

12 December 2020

The Steap proteins are metalloreductases

1 reference

12 December 2020

Molecular regulation of copper excretion in the liver

1 reference

12 December 2020

The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release

1 reference

12 December 2020

Copper and carcinogenesis

1 reference

12 December 2020

Ligand-regulated transport of the Menkes copper P-type ATPase efflux pump from the Golgi apparatus to the plasma membrane: a novel mechanism of regulated trafficking

1 reference

12 December 2020

Sodium diethyldithiocarbamate, an AIDS progression inhibitor and a copper-binding compound, has proteasome-inhibitory and apoptosis-inducing activities in cancer cells.

1 reference

12 December 2020

Antiviral effects of pyrrolidine dithiocarbamate on human rhinoviruses

1 reference

12 December 2020

The development of proteasome inhibitors as anticancer drugs

1 reference

12 December 2020

Angiogenesis: pathological, prognostic, and growth-factor pathways and their link to trial design and anticancer drugs

1 reference

12 December 2020

Angiogenesis and Cancer Control: From Concept to Therapeutic Trial

1 reference

12 December 2020

Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease.

1 reference

12 December 2020

Considerations on the mechanism of the angiogenic response

1 reference

12 December 2020

The copper chaperone for superoxide dismutase

1 reference

12 December 2020

The effect of tetrathiomolybdate on cytokine expression, angiogenesis, and tumor growth in squamous cell carcinoma of the head and neck

1 reference

12 December 2020

Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells

1 reference

12 December 2020

Inhibition of Invasion and Angiogenesis by Zinc-Chelating Agent Disulfiram

1 reference

12 December 2020

Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis

1 reference

12 December 2020

A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes

1 reference

12 December 2020

10.1517/14728222.12.6.739

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18479220%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18479220%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

18479220

1 reference