Wikidata

(Q812784)

English

BCL2 associated agonist of cell death

mammalian protein found in Homo sapiens

  • BCL2-binding component 6
  • BCL2-antagonist of cell death protein
  • bcl-2-binding component 6
  • BCL2-binding protein
  • bcl-XL/Bcl-2-associated death promoter
  • bcl2-associated agonist of cell death
  • bcl2 antagonist of cell death
  • BAD
  • bcl-2-like protein 8
  • BCL-X/BCL-2 binding protein
  • bcl2-L-8
  • bcl-associated death protein
In more languages

Statements

molecular function
protein binding
determination method
IPI
27 references
retrieved
8 April 2019
stated in
Pore-forming activity of BAD is regulated by specific phosphorylation and structural transitions of the C-terminal part
GOA
curator
UniProt
UniProt protein ID
Q92934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3
GOA
curator
UniProt
UniProt protein ID
Q92934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Aven, a novel inhibitor of caspase activation, binds Bcl-xL and Apaf-1
GOA
curator
UniProt
UniProt protein ID
Q92934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Identification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylation
GOA
curator
UniProt
UniProt protein ID
Q92934
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
PTH inactivates the AKT survival pathway in the colonic cell line Caco-2
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Structure homology and interaction redundancy for discovering virus-host protein interactions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Identification of novel in vivo phosphorylation sites of the human proapoptotic protein BAD: pore-forming activity of BAD is regulated by phosphorylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
The growth-promoting activity of the Bad protein in chicken embryo fibroblasts requires binding to protein 14-3-3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
BimL directly neutralizes Bcl-xL to promote Bax activation during UV-induced apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Crystal structure of a BCL-W domain-swapped dimer: implications for the function of BCL-2 family proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Bcl-x(L) sequesters its C-terminal membrane anchor in soluble, cytosolic homodimers
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Protection from rapamycin-induced apoptosis by insulin-like growth factor-I is partially dependent on protein kinase C signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Dimerization properties of human BAD. Identification of a BH-3 domain and analysis of its binding to mutant BCL-2 and BCL-XL proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Transcriptomic and proteomic approach to studying SNX-2112-induced K562 cells apoptosis and anti-leukemia activity in K562-NOD/SCID mice
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
retrieved
8 April 2019
stated in
The BH3-only protein Bad confers breast cancer taxane sensitivity through a nonapoptotic mechanism
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92934
determination method
IPI
cell component
biological process
Gene Atlas image
PBB GE BAD 1861 at fs.png
732 × 530; 11 KB
0 references

Identifiers

MeSH descriptor ID
D051025
subject named as
bcl-Associated Death Protein
0 references
Freebase ID
/m/0275_qk
0 references
 
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