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The aging kidney

scientific article published on 09 July 2008

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10 January 2020

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The aging kidney (English)

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10 January 2020

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Xin J Zhou

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10 January 2020

Dinesh Rakheja

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10 January 2020

Xueqing Yu

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Ramesh Saxena

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Nosratola D Vaziri

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10 January 2020

Fred G Silva

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9 July 2008

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10 January 2020

Kidney International

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10 January 2020

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https://scigraph.springernature.com/pub.10.1038/ki.2008.319

0 references

The aging kidney: role of endothelial oxidative stress and inflammation

1 reference

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Kidney aging: from phenotype to genetics

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7 January 2021

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The aging kidney: a review--part II.

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7 January 2021

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The aging kidney: a review -- part I.

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Renal senescence in 2008: progress and challenges

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Renal transplantation: older recipients and donors

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Longitudinal studies on the rate of decline in renal function with age.

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Prospective study of progression of kidney dysfunction in community-dwelling older adults

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Sequential changes in renal function tests in the old old: results from the Bronx Longitudinal Aging Study

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7 January 2021

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Serum creatinine and blood urea nitrogen over a six-year period in the very old. Creatinine and BUN in the very old

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7 January 2021

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Age-related increase in plasma urea level and decrease in fractional urea excretion: clinical application in the syndrome of inappropriate secretion of antidiuretic hormone

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Renal handling of drugs in the healthy elderly. Creatinine clearance underestimates renal function and pharmacokinetics remain virtually unchanged

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Prediction of creatinine clearance from serum creatinine

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A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group

1 reference

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National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification

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7 January 2021

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Difference in estimated GFR with two different formulas in elderly individuals.

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Comparing the Cockcroft-Gault and MDRD equations for calculation of GFR and drug doses in the elderly.

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7 January 2021

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Use of GFR equations to adjust drug doses in an elderly multi-ethnic group--a cautionary tale.

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Cystatin C reference values and aging

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Renal hemodynamic response to maximal vasodilating stimulus in healthy older subjects

1 reference

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7 January 2021

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Gender and the renal nitric oxide synthase system in healthy humans.

1 reference

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7 January 2021

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Asymmetric dimethylarginine, blood pressure, and renal perfusion in elderly subjects

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Functional changes in the ageing kidney: is there a role for asymmetric dimethylarginine?

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Renal function in the elderly: impact of hypertension and cardiac function

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7 January 2021

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Hyperkalemia in the elderly: drugs exacerbate impaired potassium homeostasis

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The influence of age on the renal response to water deprivation in man

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7 January 2021

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Urine-concentrating ability in the aging kidney

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7 January 2021

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Water balance in elderly people: is there a deficiency of vasopressin?

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Preliminary experience with the use of oral linezolid in infants for the completion of antibiotic therapy in the outpatient setting after admission to the pediatric intensive care unit

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Renal function, erythropoietin, and anemia of older persons: the InCHIANTI study.

1 reference

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Anemia in the elderly: current understanding and emerging concepts

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7 January 2021

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Serum erythropoietin and aging: a longitudinal analysis

1 reference

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7 January 2021

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Unexplained anaemia in older persons is characterised by low erythropoietin and low levels of pro-inflammatory markers

1 reference

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7 January 2021

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Reduced erythropoietin secretion in senile anemia

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Falls are associated with decreased renal function and insufficient calcitriol production by the kidney

1 reference

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7 January 2021

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In elderly men and women treated for osteoporosis a low creatinine clearance of <65 ml/min is a risk factor for falls and fractures

1 reference

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7 January 2021

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Impaired insulin secretion of aging: Role of renal failure and hyperparathyroidism

1 reference

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7 January 2021

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Mechanisms of the age-associated deterioration in glucose tolerance: contribution of alterations in insulin secretion, action, and clearance

1 reference

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7 January 2021

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Relationship between muscle sympathetic nerve activity and large artery mechanical vessel wall properties in renal transplant patients

1 reference

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Sympathetic-vascular interactions: further evidence in kidney transplantation

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7 January 2021

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Intrarenal vascular changes with age and disease

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What is 'nephrosclerosis'? lessons from the US, Japan, and Mexico.

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Histologic features of atherosclerosis and hypertension from autopsies of young individuals in a defined geographic population: the Bogalusa Heart Study

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Influence of arteriolar hyalinization on arterial intimal fibroplasia in the renal cortex of subjects in the United States, Peru, and Bolivia, applicable also to other populations

1 reference

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7 January 2021

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Hypertension, glomerular number, and birth weight in African Americans and white subjects in the southeastern United States.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Comparison of size of juxtamedullary and outer cortical glomeruli in normal adult kidney

1 reference

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7 January 2021

based on heuristic

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Glomerular number and size in relation to age, kidney weight, and body surface in normal man

1 reference

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7 January 2021

based on heuristic

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Relationship between vascular disease and age-associated changes in the human kidney

1 reference

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7 January 2021

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Tubular atrophy in the end-stage kidney: a lectin and immunohistochemical study.

1 reference

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7 January 2021

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Is the Diverticulum of the Distal and Collecting Tubules a Preliminary Stage of the Simple Cyst in the Adult?

1 reference

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7 January 2021

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The incidence of simple renal cyst by computed tomography

1 reference

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7 January 2021

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Hemodynamically mediated glomerular injury and the progressive nature of kidney disease

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Morphometric study of arterioles and glomeruli in the aging kidney suggests focal loss of autoregulation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Determinants of Glomerular Volume in Different Cortical Zones of the Human Kidney

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Hypoxia and expression of hypoxia-inducible factor in the aging kidney.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Age-Dependent Expression of Fibrosis-Related Genes and Collagen Deposition in Rat Kidney Cortex

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

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1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Advanced glycation endproduct (AGE) receptor 1 is a negative regulator of the inflammatory response to AGE in mesangial cells

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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TIMP-1 promotes age-related renal fibrosis through upregulating ICAM-1 in human TIMP-1 transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Expert consensus document on arterial stiffness: methodological issues and clinical applications

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Proteinuria: a link to understanding changes in vascular compliance?

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Elevated pulse pressure is associated with low renal function in elderly patients with isolated systolic hypertension

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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The relationship between magnitude of proteinuria reduction and risk of end-stage renal disease: results of the African American study of kidney disease and hypertension

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

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Arterial aging: pathophysiological principles

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Associations between retinal microvascular abnormalities and declining renal function in the elderly population: the Cardiovascular Health Study

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Reduction in albuminuria translates to reduction in cardiovascular events in hypertensive patients: losartan intervention for endpoint reduction in hypertension study

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

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The effect of a lower target blood pressure on the progression of kidney disease: long-term follow-up of the modification of diet in renal disease study

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

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Differential impact of blood pressure-lowering drugs on central aortic pressure and clinical outcomes: principal results of the Conduit Artery Function Evaluation (CAFE) study

1 reference

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7 January 2021

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Molecular Biology of Aging

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Senescence of renal cells: molecular basis and clinical implications

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

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Telomere shortening and ageing.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Reactive oxygen species and molecular regulation of renal oxygenation

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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The function of hypoxia-inducible factor 1 (HIF-1) is impaired in senescent mice

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

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Telomere length assessment: biomarker of chronic oxidative stress?

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of nitric oxide synthase activity by early and advanced glycation end products in cultured rabbit proximal tubular epithelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Sexual dimorphism in the aging kidney: Effects on injury and nitric oxide system

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

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Estrogen selectively up-regulates eNOS and nNOS in reproductive arteries by transcriptional mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

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Protective effect of the inhibition of the renin-angiotensin system on aging

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Enalapril and losartan attenuate mitochondrial dysfunction in aged rats

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Association of renal injury with nitric oxide deficiency in aged SHR: prevention by hypertension control with AT1 blockade

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of aging in mice by the hormone Klotho

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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inferred from DOI database lookup

Klotho as a regulator of oxidative stress and senescence

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Iron chelation and a free radical scavenger suppress angiotensin II-induced downregulation of klotho, an anti-aging gene, in rat.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

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The emerging role of the fibroblast growth factor-23-klotho axis in renal regulation of phosphate homeostasis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Recent advances in renal tubular calcium reabsorption

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Klotho: an antiaging protein involved in mineral and vitamin D metabolism

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Klotho gene polymorphisms associated with bone density of aged postmenopausal women

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of polymorphisms of the androgen receptor and klotho genes with bone mineral density in Japanese women.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of human aging with a functional variant of klotho

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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inferred from DOI database lookup

A homozygous missense mutation in human KLOTHO causes severe tumoral calcinosis

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcriptional analysis of the molecular basis of human kidney aging using cDNA microarray profiling

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

How diet influences the aging process of the rat.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Long-term caloric restriction ameliorates the decline in diastolic function in humans.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Calorie Restriction in Biosphere 2: Alterations in Physiologic, Hematologic, Hormonal, and Biochemical Parameters in Humans Restricted for a 2-Year Period

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

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Single membrane tether extraction from adult and neonatal dermal microvascular endothelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

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Chronic nephropathy in ad libitum overfed Sprague-Dawley rats and its early attenuation by increasing degrees of dietary (caloric) restriction to control growth

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Calorie restriction modulates renal expression of sterol regulatory element binding proteins, lipid accumulation, and age-related renal disease

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of age and caloric restriction on lipid peroxidation: measurement of oxidative stress by F2-isoprostane levels

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of apoptosis by calorie restriction in aged kidney

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

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Live and deceased donor kidney transplantation in patients aged 75 years and older in the United States

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Renal transplantation in the elderly

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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inferred from DOI database lookup

How old is old for transplantation?

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

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Renal transplantation in elderly patients older than 70 years of age: results from the Scientific Registry of Transplant Recipients

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Expanded criteria donors for kidney transplantation.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

The broad spectrum of quality in deceased donor kidneys

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Improving the prediction of donor kidney quality: deceased donor score and resistive indices

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Graft survival following living-donor renal transplantation: a comparison of tacrolimus and cyclosporine microemulsion with mycophenolate mofetil and steroids

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Outcome in recipients of dual kidney transplants: an analysis of the dual registry patients

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Dual-kidney transplantation with organs from expanded criteria donors: a long-term follow-up

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Long-Term Outcome of Renal Transplantation from Older Donors

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Ways to boost kidney transplant viability: a real need for the best use of older donors

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of replicative senescence in chronic allograft nephropathy.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Age-dependent glomerular damage in the rat. Dissociation between glomerular injury and both glomerular hypertension and hypertrophy. Male gender as a primary risk factor

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Glomerular capillary network of cortical nephrons is reduced in male but not in female aging rats.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

Glomerulosclerosis and tubulointerstitial fibrosis are attenuated with 17beta-estradiol in the aging Dahl salt sensitive rat.

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

A systematic look at an old problem

1 reference

https://api.crossref.org/works/10.1038%2FKI.2008.319

7 January 2021

based on heuristic

inferred from DOI database lookup

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