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ICER expression inhibits leukemia phenotype and controls tumor progression
scientific article published on 11 September 2008
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18784739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784739%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
title
ICER expression inhibits leukemia phenotype and controls tumor progression
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18784739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784739%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
main subject
tumor progression
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inferred from title
author
Martina Pigazzi
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
18784739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784739%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
Giuseppe Basso
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4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18784739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784739%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
author name string
E Manara
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2
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Europe PubMed Central
PubMed publication ID
18784739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784739%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
E Baron
series ordinal
3
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Europe PubMed Central
PubMed publication ID
18784739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784739%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
publication date
11 September 2008
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18784739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784739%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
published in
Leukemia
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18784739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784739%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
volume
22
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18784739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784739%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
issue
12
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Europe PubMed Central
PubMed publication ID
18784739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784739%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
page(s)
2217-2225
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18784739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784739%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
exact match
https://scigraph.springernature.com/pub.10.1038/leu.2008.244
0 references
cites work
Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ICER-IIgamma is a tumor suppressor that mediates the antiproliferative activity of cAMP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Degradation of the inducible cAMP early repressor (ICER) by the ubiquitin-proteasome pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of transcriptional activation of cAMP-responsive element-binding protein CREB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional regulation by the phosphorylation-dependent factor CREB
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inducible cAMP early repressor, an endogenous antagonist of cAMP responsive element-binding protein, evokes neuronal apoptosis in vitro.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of extracellular signal-regulated kinase 5 reduces cardiac apoptosis and dysfunction via inhibition of a phosphodiesterase 3A/inducible cAMP early repressor feedback loop
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coupling cAMP signaling to transcription in the liver: pivotal role of CREB and CREM.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ICER reverses tumorigenesis of rat prostate tumor cells without affecting cell growth
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
cAMP response element binding protein (CREB) overexpression CREB has been described as critical for leukemia progression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potential role of CREB as a prognostic marker in acute myeloid leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
VEGFR-1 (FLT-1), beta1 integrin, and hERG K+ channel for a macromolecular signaling complex in acute myeloid leukemia: role in cell migration and clinical outcome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
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7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple gene expression analyses in paraffin-embedded tissues by TaqMan low-density array: Application to hedgehog and Wnt pathway analysis in ovarian endometrioid adenocarcinoma
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
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7 January 2021
based on heuristic
inferred from DOI database lookup
Human ATP-binding cassette transporter TaqMan low-density array: analysis of macrophage differentiation and foam cell formation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
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7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CREB is a critical regulator of normal hematopoiesis and leukemogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RUNX1 DNA-binding mutants, associated with minimally differentiated acute myelogenous leukemia, disrupt myeloid differentiation.
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FLEU.2008.244
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7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of NF-kappa B by the human T cell leukemia virus type I Tax oncoprotein is associated with ubiquitin-dependent relocalization of I kappa B kinase
1 reference
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Crossref
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https://api.crossref.org/works/10.1038%2FLEU.2008.244
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7 January 2021
based on heuristic
inferred from DOI database lookup
MEK blockade converts AML differentiating response to retinoids into extensive apoptosis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting transcription factors in acute leukemia in children
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Therapeutic application of small interfering RNA directed against bcr-abl transcripts to a patient with imatinib-resistant chronic myeloid leukaemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synergistic interactions between vorinostat and sorafenib in chronic myelogenous leukemia cells involve Mcl-1 and p21CIP1 down-regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of steroidogenesis and the steroidogenic acute regulatory protein by a member of the cAMP response-element binding protein family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inducible cAMP early repressor suppresses gastrin-mediated activation of cyclin D1 and c-fos gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Jak3- and JNK-dependent vascular endothelial growth factor expression in cutaneous T-cell lymphoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STAT3 mediates bone marrow mesenchymal stem cell VEGF production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Curcumin inhibits tumor growth and angiogenesis in ovarian carcinoma by targeting the nuclear factor-kappaB pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PC12 cells regulate inducible cyclic AMP (cAMP) element repressor expression to differentially control cAMP response element-dependent transcription in response to nerve growth factor and cAMP.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inducible cAMP early repressor splice variants ICER I and IIgamma both repress transcription of c-fos and chromogranin A.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ICER induced by hyperglycemia represses the expression of genes essential for insulin exocytosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of RelB-mediated manganese superoxide dismutase expression reveals a primary mechanism for radiosensitization effect of 1alpha,25-dihydroxyvitamin D(3) in prostate cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oestrogen signalling inhibits invasive phenotype by repressing RelB and its target BCL2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
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7 January 2021
based on heuristic
inferred from DOI database lookup
Ras/ERK1/2-mediated STAT3 Ser727 phosphorylation by familial medullary thyroid carcinoma-associated RET mutants induces full activation of STAT3 and is required for c-fos promoter activation, cell mitogenicity, and transformation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of PDZ-binding kinase (PBK) is regulated by cell cycle-specific transcription factors E2F and CREB/ATF.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CREB regulates Meis1 expression in normal and malignant hematopoietic cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Switching leukemia cell phenotype between life and death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of c-Fos/JunD in protecting stress-induced cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MAPK signal pathways in the regulation of cell proliferation in mammalian cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor-alpha activates transcription of inducible repressor form of 3',5'-cyclic adenosine 5'-monophosphate-responsive element binding modulator and represses P450 aromatase and inhibin alpha-subunit expression in rat ovarian granulos
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of phosphodiesterase 3 and inducible cAMP early repressor in the heart
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Surface expression of GABAA receptors is transcriptionally controlled by the interplay of cAMP-response element-binding protein and its binding partner inducible cAMP early repressor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation-dependent degradation of transgenic CREB protein initiated by heterodimerization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CREB--a real culprit in oncogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FLEU.2008.244
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/LEU.2008.244
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18784739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784739%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
Dimensions Publication ID
1031517896
0 references
PubMed publication ID
18784739
1 reference
stated in
Europe PubMed Central
PubMed publication ID
18784739
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784739%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 January 2020
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