(Q81966674)

English

Proliferative signals mediated by CD28 superagonists require the exchange factor Vav1 but not phosphoinositide 3-kinase in primary peripheral T cells

scientific article published on 01 September 2008

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scholarly article

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14 January 2020

Proliferative signals mediated by CD28 superagonists require the exchange factor Vav1 but not phosphoinositide 3-kinase in primary peripheral T cells (English)

1 reference

Europe PubMed Central

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14 January 2020

Kirsty McPherson

4

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14 January 2020

Klaus Okkenhaug

5

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14 January 2020

author name string

Tea Gogishvili

1

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14 January 2020

Fernando Elias

2

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14 January 2020

Juliet L Emery

3

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14 January 2020

Thomas Hünig

6

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14 January 2020

Kevin M Dennehy

7

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14 January 2020

publication date

1 September 2008

1 reference

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14 January 2020

European Journal of Immunology

1 reference

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14 January 2020

38

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14 January 2020

9

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14 January 2020

2528-2533

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14 January 2020

Activation and inhibition of lymphocytes by costimulation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Role of CD28 co-stimulation in generation and maintenance of virus-specific T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Growth factor receptor-bound protein 2 SH2/SH3 domain binding to CD28 and its role in co-signaling

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

A point mutation in CD28 distinguishes proliferative signals from survival signals

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitogenic CD28 signals require the exchange factor Vav1 to enhance TCR signaling at the SLP-76-Vav-Itk signalosome

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitogenic signals through CD28 activate the protein kinase Ctheta-NF-kappaB pathway in primary peripheral T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Cutting edge: monovalency of CD28 maintains the antigen dependence of T cell costimulatory responses

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Topological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonists

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

CD28-mediated induction of proliferation in resting T cells in vitro and in vivo without engagement of the T cell receptor: evidence for functionally distinct forms of CD28

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of a soluble CD28-Fab complex

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

T lymphocyte costimulation mediated by reorganization of membrane microdomains

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Itk is not essential for CD28 signaling in naive T cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of Lck activity by CD4 and CD28 in the immunological synapse

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

A dose-dependent requirement for the proline motif of CD28 in cellular and humoral immunity revealed by a targeted knockin mutant

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Antigen receptor signalling: a distinctive role for the p110delta isoform of PI3K.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

The p110delta isoform of phosphoinositide 3-kinase controls clonal expansion and differentiation of Th cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

The oncogene product Vav is a crucial regulator of primary cytotoxic T cell responses but has no apparent role in CD28-mediated co-stimulation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Vav1 transduces T cell receptor signals to the activation of phospholipase C-gamma1 via phosphoinositide 3-kinase-dependent and -independent pathways.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Costimulation through NKG2D enhances murine CD8+ CTL function: similarities and differences between NKG2D and CD28 costimulation.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

NKG2D-mediated signaling requires a DAP10-bound Grb2-Vav1 intermediate and phosphatidylinositol-3-kinase in human natural killer cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Vav-Dependent and Vav-Independent Phosphatidylinositol 3-Kinase Activation in Murine B Cells Determined by the Nature of the Stimulus

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Grb2 and the non-T cell activation linker NTAL constitute a Ca(2+)-regulating signal circuit in B lymphocytes.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Autonomous induction of proliferation, JNK and NF-alphaB activation in primary resting T cells by mobilized CD28

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200838223

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/EJI.200838223

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18792405%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18792405%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

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