(Q46348775)

21 December 2017

title

Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation (English)

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21 December 2017

author

Lawrence P. Kane

4

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21 December 2017

Arthur Weiss

9

object named as

Arthur Weiss

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21 December 2017

author name string

Pietro G Andres

1

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21 December 2017

Kimberly C Howland

2

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21 December 2017

Ajay Nirula

3

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21 December 2017

Luke Barron

5

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21 December 2017

Douglas Dresnek

6

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21 December 2017

Ali Sadra

7

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21 December 2017

John Imboden

8

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21 December 2017

Abul K Abbas

10

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21 December 2017

language of work or name

English

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publication date

7 March 2004

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21 December 2017

published in

Nature Immunology

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21 December 2017

volume

5

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21 December 2017

issue

4

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21 December 2017

page(s)

435-442

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21 December 2017

The duration of antigenic stimulation determines the fate of naive and effector T cells.

cites work

1 reference

CD28 as a molecular amplifier extending TCR ligation and signaling capabilities.

21 January 2018

1 reference

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

21 January 2018

1 reference

Differential phosphorylation of the T lymphocyte costimulatory receptor CD28. Activation-dependent changes and regulation by protein kinase C.

21 January 2018

1 reference

CD28 of T lymphocytes associates with phosphatidylinositol 3-kinase

21 January 2018

1 reference

T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif

21 January 2018

1 reference

Stimulation of CD28 triggers an association between CD28 and phosphatidylinositol 3-kinase in Jurkat T cells

21 January 2018

1 reference

Ligation of CD28 receptor by B7 induces formation of D-3 phosphoinositides in T lymphocytes independently of T cell receptor/CD3 activation

21 January 2018

1 reference

T cell antigen CD28 binds to the GRB-2/SOS complex, regulators of p21ras

21 January 2018

1 reference

The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.

21 January 2018

1 reference

Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation

21 January 2018

1 reference

The role of Tec protein-tyrosine kinase in T cell signaling

21 January 2018

1 reference

Negative-feedback regulation of CD28 costimulation by a novel mitogen-activated protein kinase phosphatase, MKP6.

21 January 2018

1 reference

Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy

21 January 2018

1 reference

Two distinct intracytoplasmic regions of the T-cell adhesion molecule CD28 participate in phosphatidylinositol 3-kinase association

21 January 2018

1 reference

Novel role of phosphatidylinositol 3-kinase in CD28-mediated costimulation

21 January 2018

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CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation

21 January 2018

1 reference

Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo

21 January 2018

1 reference

A point mutation in CD28 distinguishes proliferative signals from survival signals

21 January 2018

1 reference

Tec kinase is involved in transcriptional regulation of IL-2 and IL-4 in the CD28 pathway

21 January 2018

1 reference

Antigen-independent Th2 cell differentiation by stimulation of CD28: regulation via IL-4 gene expression and mitogen-activated protein kinase activation

21 January 2018

1 reference

Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells

21 January 2018

1 reference

Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines

21 January 2018

1 reference

Expression of bcl-X(L) restores cell survival, but not proliferation off effector differentiation, in CD28-deficient T lymphocytes

21 January 2018

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Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL.

21 January 2018

1 reference

Efficient CD28 signalling leads to increases in the kinase activities of the TEC family tyrosine kinase EMT/ITK/TSK and the SRC family tyrosine kinase LCK.

21 January 2018

1 reference

Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells

21 January 2018

1 reference

Cellular signaling: pivoting around PDK-1.

21 January 2018

1 reference

HgCl2-induced interleukin-4 gene expression in T cells involves a protein kinase C-dependent calcium influx through L-type calcium channels

21 January 2018

1 reference

A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans

21 January 2018

1 reference

Topological requirements and signaling properties of T cell-activating, anti-CD28 antibody superagonists

21 January 2018

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CD28/CTLA-4 and CD80/CD86 families: signaling and function

21 January 2018

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Activation of phosphatidylinositol-3-kinase in Jurkat T cells depends on the presence of the p56lck tyrosine kinase

21 January 2018

1 reference

The SH3 domain of p56lck is involved in binding to phosphatidylinositol 3'-kinase from T lymphocytes

21 January 2018

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Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)

21 January 2018

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Regulation of protein kinase Ctheta function during T cell activation by Lck-mediated tyrosine phosphorylation

21 January 2018

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Reconstitution of Btk signaling by the atypical tec family tyrosine kinases Bmx and Txk.

21 January 2018

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Absence of B7-dependent responses in CD28-deficient mice

21 January 2018

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7 January 2021

The roles of CD28 and CD40 ligand in T cell activation and tolerance

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7 January 2021

Duration of TCR stimulation determines costimulatory requirement of T cells

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7 January 2021

T lymphocyte costimulation mediated by reorganization of membrane microdomains

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7 January 2021

Mutation of Tec family kinases alters T helper cell differentiation

1 reference

7 January 2021

Protein kinase C-mediated calcium entry dependent upon dihydropyridine sensitive channels: a T cell receptor-coupled signaling pathway involved in IL-4 synthesis.

1 reference

7 January 2021

IL-4 secretion and histamine release by human basophils are differentially regulated by protein kinase C activation

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7 January 2021

Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1

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7 January 2021

Triggering of T cell proliferation through CD28 induces GATA-3 and promotes T helper type 2 differentiation in vitro and in vivo

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7 January 2021

Identifiers

DOI

10.1038/NI1044

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21 December 2017

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21 December 2017