(Q82805940)

English

Effect of inhibition of cytochrome P450 enzymes 2D6 and 3A4 on the pharmacokinetics of intravenous oxycodone: a randomized, three-phase, crossover, placebo-controlled study

scientific article published on 01 January 2011

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142269%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Effect of inhibition of cytochrome P450 enzymes 2D6 and 3A4 on the pharmacokinetics of intravenous oxycodone: a randomized, three-phase, crossover, placebo-controlled study (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142269%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

pharmacokinetics

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based on heuristic

inferred from title

3

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Nora M Hagelberg

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17 January 2020

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Juha Grönlund

1

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17 January 2020

Teijo I Saari

2

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17 January 2020

Pertti J Neuvonen

4

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17 January 2020

Kari Laine

5

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17 January 2020

Klaus T Olkkola

6

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17 January 2020

publication date

1 January 2011

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17 January 2020

Clinical Drug Investigation

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142269%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

31

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17 January 2020

3

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17 January 2020

143-153

1 reference

Europe PubMed Central

PubMed publication ID

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17 January 2020

Predicting aberrant drug behavior in patients treated for chronic pain: importance of abuse history

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

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inferred from PubMed ID database lookup

The effect of erythromycin, fluvoxamine, and their combination on the pharmacokinetics of ropivacaine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of oxycodone, noroxycodone, oxymorphone, and noroxymorphone in human plasma by liquid chromatography-electrospray-tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of Recovery from Outpatient General Anaesthesia with a Simple Ocular Test

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A potentially hazardous interaction between erythromycin and midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of erythromycin and fluvoxamine on the pharmacokinetics of intravenous lidocaine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of erythromycin and itraconazole on the pharmacokinetics of oral lignocaine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Morphine-fluoxetine interactions in healthy volunteers: analgesia and side effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of blocking CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of the critical flicker fusion effects of serotonin reuptake inhibitors by concomitant pupillary changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of itraconazole on the pharmacokinetics and pharmacodynamics of intravenously and orally administered oxycodone

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental human pain models: a review of standardised methods for preclinical testing of analgesics

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of the CYP2D6 genotype on post-operative intravenous oxycodone analgesia

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid and sensitive high performance liquid chromatographic method for the determination of itraconazole and its hydroxy-metabolite in human serum

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacokinetics and metabolism of oxycodone after intramuscular and oral administration to healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of erythromycin and itraconazole on the pharmacokinetics of intravenous lignocaine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP2D6 genotyping by a multiplex primer extension reaction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: role of circulating active metabolites

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of voriconazole on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intestinal first-pass metabolism of CYP3A4 substrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacokinetics of oxycodone after intravenous injection in adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exposure to oral oxycodone is increased by concomitant inhibition of CYP2D6 and 3A4 pathways, but not by inhibition of CYP2D6 alone

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pencil and paper tests-sensitivity to psychotropic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of telithromycin on the pharmacokinetics and pharmacodynamics of oral oxycodone

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of paroxetine, fluoxetine and norfluoxetine in fish tissues using pressurized liquid extraction, mixed mode solid phase extraction cleanup and liquid chromatography-tandem mass spectrometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-dose and steady-state pharmacokinetics and pharmacodynamics of oxycodone in patients with cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voriconazole drastically increases exposure to oral oxycodone

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mucosa of the small intestine: how clinically relevant as an organ of drug metabolism?

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential sensitivity of three experimental pain models in detecting the analgesic effects of transdermal fentanyl and buprenorphine

1 reference

https://pubmed.ncbi.nlm.nih.gov/21142269

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2165/11539950-000000000-00000

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142269%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21142269%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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